Mini-Review Article
Neonatal Sickle Cell Disease Assessment in Rural Indian Community: Demand for Point of Care Testing (POCT)
Neonatal Sickle Cell Disease Assessment in Rural Indian Community: Demand for Point of Care Testing (POCT)

Sarita Anil Shinde; Anita Deepak Deshmukh; Umesh Kisanrao More

Volume 7, Issue 1 , January 2024, Pages 1-8

https://doi.org/10.26655/JMCHEMSCI.2024.1.1

Abstract
  The most prevalent hemoglobinopathy is sickle cell disease, which is followed by β-thalassemia and thalassemia syndrome. The Mediterranean region, Middle East, Indian subcontinent, ...  Read More
Original Article
Immunohistochemical comparison of CD44 and Hypoxia Inducible Factor-1 Alpha (HIF-1α) in Oral Squamous Cell Carcinoma and Oral Epithelial Dysplasia: A comparative study
Immunohistochemical comparison of CD44 and Hypoxia Inducible Factor-1 Alpha (HIF-1α) in Oral Squamous Cell Carcinoma and Oral Epithelial Dysplasia: A comparative study

Doaa E.A. Salama; Abdulkarim Hasan; Gihan A. Balbola; Amany M. Taha; Hanaa M. Abdel-Samia; Azza Kamal Taha; Ghada S.I. Radwan; Rania Rifat Abdel-Maqsoud; Mohamed Fayek Abdelaleem; Abdulhadi Samman; Mehenaz Hanbazazh; Mohammed A. Alghamdi; Rajab A. Alzahrani; Mohamed Nady; Mostafa Ali M. Ibrahim; Hesham Abbas; Diana Z. Saad; Essam Mandour

Volume 7, Issue 1 , January 2024, Pages 9-23

https://doi.org/10.26655/JMCHEMSCI.2024.1.2

Abstract
  This study aimed to evaluate the expression of hypoxia inducible factor-1 alpha (HIF-1α) and CD44 markers to detect their potential role in the progression of oral epithelial ...  Read More
Original Article
Oxidative Stress and Cognitive Performance in Children with Temporal Lobe Epilepsy
Oxidative Stress and Cognitive Performance in Children with Temporal Lobe Epilepsy

Marwa Elhady; Heba Tawfik Okda; Mohamed Farouk Ahmed; Rasha M. Gouda; Rasha Sobhy Elattar; Seham Eelsaid Abdelsadek; Talal Abd Allah Mohammed Dawa; Mohammad Fathi Abdulsalam; Fathy Mahmoud Mansour; Adel M. Othman; Doaa Ibrahim Hassan Ibrahim; Shaimaa A. Maklad; Shahinaz El Attar; Walaa Shipl; Rayyh A.M. Saleh; Esraa Ali

Volume 7, Issue 1 , January 2024, Pages 24-33

https://doi.org/10.26655/JMCHEMSCI.2024.1.3

Abstract
  Background: Cognitive impairment represents a major but under-determined comorbidity in children with temporal lobe epilepsy. Exposure to oxidation stress may induce cellular damage ...  Read More
Original Article
Correlation of Relation of Serum Prolactin Level to Child-Pugh Score in Cirrhosis of Liver in Assessing Disease Severity
Correlation of Relation of Serum Prolactin Level to Child-Pugh Score in Cirrhosis of Liver in Assessing Disease Severity

Sujitha Vemanamanda; Srinivasa S.V

Volume 7, Issue 1 , January 2024, Pages 34-41

https://doi.org/10.26655/JMCHEMSCI.2024.1.4

Abstract
  Aim: To find the accuracy of prolactin levels and identify the severity and complications.Materials & Methods: This was a cross-sectional study performed in the Department of Medicine ...  Read More
Original Article
Positive Correlation Found Between CXCL12/PLK1 Expression and T Stage of Clear Cell Renal Cell Carcinoma
Positive Correlation Found Between CXCL12/PLK1 Expression and T Stage of Clear Cell Renal Cell Carcinoma

Aditya Sita Sari; Anny Setijo Rahaju; Nila Kurniasari

Volume 7, Issue 1 , January 2024, Pages 42-52

https://doi.org/10.26655/JMCHEMSCI.2024.1.5

Abstract
  Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer and the incidence is steadily increasing. T Stage is one of the most important information to assess ...  Read More
Mini-Review Article
Role of Lymphocytes and Atyphical Lymphocytes in Dengue Hemorrhagic Fever: A Literature Review
Role of Lymphocytes and Atyphical Lymphocytes in Dengue Hemorrhagic Fever: A Literature Review

Ahmad Fahrudi Setiawan; Yuyun Yueniwati Prabowowati Wajib; Kusworini Handono; Setyawan Purnomo Sakti

Volume 7, Issue 1 , January 2024, Pages 53-58

https://doi.org/10.26655/JMCHEMSCI.2024.1.6

Abstract
  Dengue hemorrhagic fever (DHF) is still a major problem in the world. It diagnosis is based on clinical and supporting examinations including leukocytes and platelets examinations, ...  Read More
Review Article
Implication of Plasma miR 122 and miR 151-3p Levels in Diagnosis and Prognosis of Acute Coronary Syndrome Patients
Implication of Plasma miR 122 and miR 151-3p Levels in Diagnosis and Prognosis of Acute Coronary Syndrome Patients

Heba Fawzy; Mohammed S. Ghareeb; Hala Mosaad

Volume 7, Issue 1 , January 2024, Pages 59-77

https://doi.org/10.26655/JMCHEMSCI.2024.1.7

Abstract
  Background: Acute coronary syndrome (ACS) has a significant morbidity and fatality rate. An early diagnosis and accurate prognosis are necessary. Therefore, biomarkers that are associated ...  Read More
Original Article
S.hermanni's Capability as an Antimalarial and Antioxidant in a Mice Model of P.berghei ANKA Infection
S.hermanni's Capability as an Antimalarial and Antioxidant in a Mice Model of P.berghei ANKA Infection

Prawesty Diah Utami; Wachjudi Kurnia; Irma Andriani Pasaribu

Volume 7, Issue 1 , January 2024, Pages 78-90

https://doi.org/10.26655/JMCHEMSCI.2024.1.8

Abstract
  Background: Malaria poses a substantial threat to healthcare systems across the globe. The escalating resistance of malaria parasites to the absence of affordable and accessible antimalarial ...  Read More
Original Article
Clinical Changes in Patterns of Moral Courage and Moral Distress Among Operating Room Nurses During COVID-19
Clinical Changes in Patterns of Moral Courage and Moral Distress Among Operating Room Nurses During COVID-19

Mahboobeh Khosravani; Ashkan Karimi; Sahar Khaki; Hamed Parnikh; Azam Moslemi; Zahra Mostafapour; Azadeh Amiri

Volume 7, Issue 1 , January 2024, Pages 91-103

https://doi.org/10.26655/JMCHEMSCI.2024.1.9

Abstract
  Healthcare personnel involved in COVID-19 care have been negatively affected by the associated excess stress. This study aimed to investigate the relationship between moral distress ...  Read More
Original Article
The Impact of Obesity and Diabetes on COVID-19 Severity
The Impact of Obesity and Diabetes on COVID-19 Severity

Asma Alanazi; Raseel Alsubaie; Wed Alwabel; Aram Alzahrani; Wasan Alenezi; Bushra Almutawa; Nada Al Eisa

Volume 7, Issue 1 , January 2024, Pages 104-115

https://doi.org/10.26655/JMCHEMSCI.2024.1.10

Abstract
  The seven human coronavirus, sever acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had started a worldwide health pandemic that raised concern regarding its severe outcomes in ...  Read More
Original Article
Eroepidemiology of Leptospirosis Among Healthy People in Zanjan, Northwest of Iran
Eroepidemiology of Leptospirosis Among Healthy People in Zanjan, Northwest of Iran

Manizhe Jozpanahi; Rojin Ahmadi; Afsaneh Ayaz; Fakhri Haghi

Volume 7, Issue 1 , January 2024, Pages 116-123

https://doi.org/10.26655/JMCHEMSCI.2024.1.11

Abstract
  Objective: A tropical disease of zoonotic origin, Leptospirosis is a public health concern, particularly in developing countries. This present investigation sought to determine the ...  Read More
Original Article
Effect of Pangasius Hypophthalmus Fish Extract on Blood Sugar and Uric Acid Levels in Alloxan-Induced Rattus Norvegicus
Effect of Pangasius Hypophthalmus Fish Extract on Blood Sugar and Uric Acid Levels in Alloxan-Induced Rattus Norvegicus

Fitri Handajani; Nabil Nabil

Volume 7, Issue 1 , January 2024, Pages 124-131

https://doi.org/10.26655/JMCHEMSCI.2024.1.12

Abstract
  Pangasius hypophthalmus fish, as a dietary source, contains vitamins and minerals that serve as antioxidants, effectively preventing oxidative stress. Diabetes mellitus is rooted in ...  Read More
Original Article
Plasma Protein Binding and Blood-to-Plasma Ratios of Atractylodin and -Eudesmol, the Bioactive Compounds from Atractylodes lancea (Thunb.) D.C.
Plasma Protein Binding and Blood-to-Plasma Ratios of Atractylodin and -Eudesmol, the Bioactive Compounds from Atractylodes lancea (Thunb.) D.C.

Anurak Cheoymang; Kesara Na-Bangchang

Volume 7, Issue 1 , January 2024, Pages 132-139

https://doi.org/10.26655/JMCHEMSCI.2024.1.13

Abstract
  Cholangiocarcinoma remains a problem in several tropical and subtropical parts of the world, especially in Southeast Asia. The study determined plasma protein binding and blood-to-plasma ...  Read More
Original Article
Risk Factors Affecting Anxiety and Depression in Malignancy Patients in Makassar
Risk Factors Affecting Anxiety and Depression in Malignancy Patients in Makassar

Tutik Harjianti; Sitti Rahmah; Andi Fachruddin Benyamin; Syakib Bakri; Hasyim Kasim; Wasis Udaya; Saidah Syamsuddin; Arifin Seweng

Volume 7, Issue 1 , January 2024, Pages 140-149

https://doi.org/10.26655/JMCHEMSCI.2024.1.14

Abstract
  Objective: This study aimed to determine the risk factors that affect anxiety and depression in patients diagnosed with malignancy in Makassar.Materials and methods: A cross-sectional ...  Read More
Original Article
Effectivity and Safety After Intravitreal Triamcinolone Acetonide and Bevacizumab Titanium Dioxide (TiO2) Nanoparticles Induced Gonadal Toxicity in Exposed Male Sprague-Dawley Rats
Effectivity and Safety After Intravitreal Triamcinolone Acetonide and Bevacizumab Titanium Dioxide (TiO2) Nanoparticles Induced Gonadal Toxicity in Exposed Male Sprague-Dawley Rats

Adeel Khalid; Asma Asghar; M. Danish; Ayesha Ijaz; Ammara Zahid; Arif Nur Muhammad Ansori; Ahmad Affan Ali Murtadlo; Rahadian Zainul

Volume 7, Issue 1 , January 2024, Pages 150-165

https://doi.org/10.26655/JMCHEMSCI.2024.1.15

Abstract
  Titanium dioxide nanoparticles (TiO2-NPs) are widely utilized as a whitish pigment with potential applications in various sectors, including cosmetics, pharmaceuticals, food production, ...  Read More
Original Article
The Association between Left Ventricular Myocardial Strains and Risk Factors of Cardiovascular Disease in a Population with Type 2 Diabetes Mellitus: A Primary Controlled Cross-Sectional Study
The Association between Left Ventricular Myocardial Strains and Risk Factors of Cardiovascular Disease in a Population with Type 2 Diabetes Mellitus: A Primary Controlled Cross-Sectional Study

Nguyen Trang Nguyen; Anh Vu Nguyen; Van Chi Le

Volume 7, Issue 1 , January 2024, Pages 166-175

https://doi.org/10.26655/JMCHEMSCI.2024.1.16

Abstract
  Background: Cardiovascular complications are the primary reason for death in diabetic patients. Speckle tracking echocardiography is the method that can detect heart systolic dysfunction ...  Read More
Review Article
A Comparison Between Intrastromal Voriconazole and Intracameral Amphotericin B in the Treatment of Resistant Fungal Keratitis between Intrastromal voriconazole and Intracameral amphotericin B in the treatment of resistant fungal keratitis
A Comparison Between Intrastromal Voriconazole and Intracameral Amphotericin B in the Treatment of Resistant Fungal Keratitis between Intrastromal voriconazole and Intracameral amphotericin B in the treatment of resistant fungal keratitis

Ahmed Nabil Elsayed Hafiz; Ahmed Mahmoud Amin; Mostafa F. Mohammed; Nour Eldin Abdelhamid; Emad A Saliem; Ahmed I Galhoom; Mohamed Mohamed-Aly Ibrahim; Shaimaa. M. Mostafa

Volume 7, Issue 1 , January 2024, Pages 176-188

https://doi.org/10.26655/JMCHEMSCI.2024.1.17

Abstract
  Background: According to reports, fungus-related keratitis accounts for roughly 50% of all bacterial keratitis instances involving therapeutic penetration keratoplasty, making it a ...  Read More
Original Article
Development, Characterization, and Influence of Proanthocyanidin Loaded PLGA Nanoparticles on Push out Bond Strength of Glass Fibre Posts Bonded with Resin Cement to Root Dentin: In Vitro Study
Development, Characterization, and Influence of Proanthocyanidin Loaded PLGA Nanoparticles on Push out Bond Strength of Glass Fibre Posts Bonded with Resin Cement to Root Dentin: In Vitro Study

Tarini Mullick; Sushruta S Hakkimane; Kishore Ginjupalli; Swathi Pai; Bharath Raja Guru; Krishnaraj Somayaji

Volume 7, Issue 1 , January 2024, Pages 189-202

https://doi.org/10.26655/JMCHEMSCI.2024.1.18

Abstract
  Partial or an incomplete penetration of bonding agent into the demineralized dentin can leave the denuded collagen fibres susceptible to degradation by photolytic enzymes. It is well ...  Read More
Original Article
Mechanism of Sodium Selenite-Induced Cataract Through Autophagy in Wistar (Rattus norvegicus) Rats
Mechanism of Sodium Selenite-Induced Cataract Through Autophagy in Wistar (Rattus norvegicus) Rats

Cicih Komariah; Jusak Nugraha; Hidayat Sujuti

Volume 7, Issue 1 , January 2024, Pages 203-214

https://doi.org/10.26655/JMCHEMSCI.2024.1.19

Abstract
  Cataracts are characterized by the clouding of the eye lens, resulting from changes in lens metabolism that can lead to lens hydration (fluid accumulation), denaturation of lens proteins, ...  Read More
Review Article
A Mini Review of Curcuma longa: Antimicrobial Properties
A Mini Review of Curcuma longa: Antimicrobial Properties

Ahmad Affan Ali Murtadlo; Arif Nur Muhammad Ansori; Viol Dhea Kharisma; Bayyinatul Muchtaromah; Muhammad Badrut Tamam; Dora Dayu Rahma Turista; Imam Rosadi; Vikash Jakhmola; Maksim Rebezov; Amaq Fadholly; Muhammad Khaliim Jati Kusala; Rahadian Zainul

Volume 7, Issue 1 , January 2024, Pages 215-221

https://doi.org/10.26655/JMCHEMSCI.2024.1.20

Abstract
  This review discusses the antimicrobial potential of Curcuma longa, a plant traditionally recognized for its medicinal properties. The emerging concern over antimicrobial resistance, ...  Read More
Cross Sectional Study
Association of Cyclin D1 Expression and Histopathological Grading of Invasive Ductal Carcinoma Breast Cancer: An Observational Cross-Sectional Study in Surabaya
Association of Cyclin D1 Expression and Histopathological Grading of Invasive Ductal Carcinoma Breast Cancer: An Observational Cross-Sectional Study in Surabaya

Dudung Lupito; Grace Ariani; Paulus Budiono Notopuro

Volume 7, Issue 1 , January 2024, Pages 222-233

https://doi.org/10.26655/JMCHEMSCI.2024.1.21

Abstract
  Breast cancer is ranked as the fifth major contributor to global cancer-related fatalities. Cyclin D1 is frequently overexpressed in cases of invasive ductal breast cancer and plays ...  Read More
Case Report
Bariatric Surgery in Patient with Atrial Septal Defect and Arrhythmogenic Right Ventricular Dysplasia: an Anesthetic Challenge
Bariatric Surgery in Patient with Atrial Septal Defect and Arrhythmogenic Right Ventricular Dysplasia: an Anesthetic Challenge

Bondan Irtani Cahyadi; Anas Alatas; Widya Istanto Nurcahyo

Volume 7, Issue 1 , January 2024, Pages 234-241

https://doi.org/10.26655/JMCHEMSCI.2024.1.22

Abstract
  Introduction: Quick and smooth recovery after bariatric surgery for morbidly obese patients may pose a challenge to anesthesiologists, especially if there is any cardiac comorbidity. ...  Read More
Original Article
Effect of Atorvastatin on Clinical Manifestations and Outcomes in Patients with COVID-19
Effect of Atorvastatin on Clinical Manifestations and Outcomes in Patients with COVID-19

Alireza Kamali; Masoumeh Sofian; Behnam Mahmodiyeh; Shamim Valibeik; Elham Farahani

Volume 7, Issue 1 , January 2024, Pages 242-249

https://doi.org/10.26655/JMCHEMSCI.2024.1.23

Abstract
  Background: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has been associated with severe respiratory disease incidence and ...  Read More
Review Article
Anti-Inflammatory Effect of Epigallocatechin Gallate on Tumor Necrosis Factor-Alpha and Interleukin-10 Expression in Pseudomonas aeruginosa-Induced Keratitis
Anti-Inflammatory Effect of Epigallocatechin Gallate on Tumor Necrosis Factor-Alpha and Interleukin-10 Expression in Pseudomonas aeruginosa-Induced Keratitis

Fariztah Sukainah Nur Fathimah; Tarosa Yodia Urolita; Annisa Karima; Ismi Zuhria; Delfitri Lutfi

Volume 7, Issue 1 , January 2024, Pages 250-261

https://doi.org/10.26655/JMCHEMSCI.2024.1.24

Abstract
  Pseudomonas aeruginosa is the most prevalent cause of keratitis, which can cause progressive corneal injury, scarring, thinning and corneal perforation. Antibiotic treatment alone is ...  Read More
Original Article
Evaluation of the Use of Antibiotics on Therapy Results of Sepsis Patients in the Intensive Care Unit (ICU) of Fatmawati Hospital, Jakarta
Evaluation of the Use of Antibiotics on Therapy Results of Sepsis Patients in the Intensive Care Unit (ICU) of Fatmawati Hospital, Jakarta

Arief Fatkhur Rohman; Maksum Radji; Alfina Rianti; Arif Rachman

Volume 7, Issue 1 , January 2024, Pages 262-274

https://doi.org/10.26655/JMCHEMSCI.2024.1.25

Abstract
  Background: High use of antibiotics in sepsis patients can lead to irrational use of antibiotics. Irrational antibiotic therapy in septic patients in the ICU increases the mortality ...  Read More