Volume 7 (2024)
Volume 6 (2023)
Volume 5 (2022)
Volume 4 (2021)
Volume 3 (2020)
Volume 2 (2019)
Volume 1 (2018)
Main Subjects = Chemical
Number of Articles: 189
Synthesis, Characterization and Biological Evaluation of Novel 3-Methyl-5-pyrazolone Derivatives
Volume 4, Issue 1 , January 2021, , Pages 42-52
Abstract
Recently, infectious diseases have increased enormously, causing a major threat to public health despite the marvelous progress in the medicinal chemistry. Fused pyrazole derivatives ... Read More
Density Functional Theory Study of 1, 4-Bis(methane sulfonyloxy)butane Tautomerization Mechanism as Anticancer Drug
Volume 4, Issue 1 , January 2021, , Pages 53-59
Abstract
This study discussed the prediction of tautomerization manner of the 1,4-bis(methane sulfonyloxy)butane in chemical reactions with an excellent and accurate quantum methods in gas phase. ... Read More
The design and effectiveness of educational package based on increased activity and cognitive, emotional and neuro-muscular activity in activities of daily living in the elderly with mild cognitive impairment
Volume 3, Issue 4 , October 2020, , Pages 345-353
Abstract
Dementia is a progressive disorder with severe cognitive decline, behavioral problems, and lack of movement in daily life activities. Simultaneous resistance training and active participation ... Read More
Synthesis of novel polymers containing Schiff base as potential antimutagenic and antimicrobial agents
Volume 3, Issue 4 , October 2020, , Pages 363-372
Abstract
In this research study, two novel polymers including Schiff base were prepared by condensation reaction of polystyrene-A-NH2 with 5-nitro-2-thiophenecarboxaldehyde/or 5-(2-nitrophenyl)-2-furancarboxaldehyde. ... Read More
Biomedical Scope of Gold Nanoparticles in Medical Sciences; an Advancement in Cancer Therapy
Volume 3, Issue 4 , October 2020, , Pages 399-407
Abstract
Nanotechnology is a vast and fast emerging area of scientific research studies resolving several complications related to conservative medication therapies, including underprivileged ... Read More
Adsorption of melphalan anticancer drug on the surface of boron nitride cage (B12N12): A comprehensive DFT study
Volume 3, Issue 3 , July 2020, , Pages 199-207
Abstract
In this study, boron nitride cage (B12N12) adsorption with Melphalan anticancer agent in solvent phase (water) was studied using the density function theory (DFT) method. First, the ... Read More
Novel unsymmetric diimines: Synthesis and biological evaluation against pathogenic microorganisms
Volume 3, Issue 3 , July 2020, , Pages 219-227
Abstract
In this research study, three new unsymmetric diimines (3a-3c) were prepared using a two-step process. The synthesized unsymmetric tetradentate diimines were elucidated by FT-IR, 1H-NMR, LC-MS, ... Read More
Antiviral activity of isoindole derivatives
Volume 3, Issue 3 , July 2020, , Pages 254-285
Abstract
The isoindole scaffolds and their related compounds are very important as they have a wide range of biological activities such as anti-inflammatory, antiarrhythmic, nootropic, anxiolytic, ... Read More
Detoxification of acetaminophen overdose using formulated carbo tablets
Volume 3, Issue 2 , April 2020, , Pages 183-198
Abstract
Acetaminophen overdose is one of severe global health challenges. In this study, adsorption technique was used to reduce acetaminophen overdose. Carbo tablets derived by wet granulation ... Read More
Development and Validation of RP-HPLC Method for Simultaneous Estimation of Three Components in cream formulation used in Hemorrhoids Disease
Volume 3, Issue 1 , January 2020, , Pages 11-21
Abstract
Developing a single analytical method for determination of individual drug from a multidrug composition is a very difficult task. The present work describes a simple, rapid, precise ... Read More![Exploring molecular docking and electronic studies of [11C]LY2795050 as a novel antagonist tracer for positron emission tomography (PET) scan of the kappa (κ) and mu (µ) opioid receptors (KOR and MOR)](data/jmcs/coversheet/591559198679.jpg)
Exploring molecular docking and electronic studies of [11C]LY2795050 as a novel antagonist tracer for positron emission tomography (PET) scan of the kappa (κ) and mu (µ) opioid receptors (KOR and MOR)
Volume 3, Issue 1 , January 2020, , Pages 22-34
Abstract
The main purpose of the present research article is the docking analysis of [11C]LY2795050 radiopharmaceutical with kappa (κ) and mu (µ) opioid receptors (KOR and MOR) and ... Read More![Microwave-assisted synthesis of phenanthro[9, 10-d]imidazole derivatives under solvent-free and one pot conditions](data/jmcs/coversheet/571561732871.jpg)
Microwave-assisted synthesis of phenanthro[9, 10-d]imidazole derivatives under solvent-free and one pot conditions
Volume 3, Issue 1 , January 2020, , Pages 41-47
Abstract
Phenanthro[9, 10-d]imidazole derivatives were synthesized with the combinations of phenanthroquinone and benzealdehyde derivatives in the presence of ammonium acetate. The microwave-assisted ... Read More
Medical implementation practice of supramolecular complex of megosin with MASGA
Volume 3, Issue 1 , January 2020, , Pages 48-54
Abstract
Drug creation based on synthesized azomethine derivatives of gossypol is of great interest with glycyrrhizic acid. Studies have shown that, in combination with glycyrrhizic acid, their ... Read More
Photosensitization of phthalocyanine for singlet oxygen generation in photodynamic therapy applications
Volume 3, Issue 1 , January 2020, , Pages 55-59
Abstract
In this work, phthalocyanine and its OCH3 derivatives were investigated to see their photosensitization characteristics for producing singlet molecular oxygen, which is important in ... Read More
A mini review: recent developments of heterocyclic chemistry in some drug discovery scaffolds synthesis
Volume 3, Issue 1 , January 2020, , Pages 71-78
Abstract
Novel developments in the synthetic techniques that facilitate rapid access to various functionalized heterocyclic compounds are essential in medicinal chemistry. They enable an expansion ... Read More
Considering different kinds of gasoline unit catalysts
Volume 3, Issue 1 , January 2020, , Pages 79-94
Abstract
The aim of this study is to investigate naphtha Gasoline unit catalysts. In two-factor catalysts, platinum or palladium was used as the active metal on the base alumina chloride, zirconia, ... Read More
A Review on Classes, Extraction, Purification and Pharmaceutical Importance of Plants Alkaloid
Volume 2, Issue 4 , July and August 2019, , Pages 130-139
Abstract
The importance of natural products in the pharmaceutical industry cannot be abated because it plays a vital role in the prevention and treatments of diseases such as cancer, malaria, ... Read More
Design, Synthesis, and Testing of Antiprotozoal Activity of Primin and Analogues
Volume 2, Issue 4 , July and August 2019, , Pages 140-143
Abstract
A set of conformationally restricted analogues of the natural product primin were synthesized as potential antiprotozoal agents. The synthesis utilizes quinone C-H functionalization ... Read More
Synthesis of Medicinally Relevant Phenyl Sulphonylamino Alkanamides and N-aryl P-toluenesulphonamides
Volume 2, Issue 4 , July and August 2019, , Pages 151-161
Abstract
Synthesis of new medicinally important phenylsulphonyl aminoalkanamides and N-aryl p-toluene sulphonamides is reported. The reaction between benzenesulphonylchloride 7 with valine gave ... Read More
Swelling Kinetics of Poly(N-Isopropylacrylamide)-Based Hydrogel and its Application as Anti-Diabetic Drugs Delivery System
Volume 2, Issue 4 , July and August 2019, , Pages 162-171
Abstract
The swelling kinetics of charantin from poly (N-isopropyl acrylamide), PNIPAM–based hydrogel, is accomplished through direct weighing, before soaking the gel in fluid/drug solution ... Read More
Effect of Temperature of Water Used For Reconstitution On Stability Of Antibiotic Dry Suspension
Volume 2, Issue 4 , July and August 2019, , Pages 177-183
Abstract
This study is carried out to test the stability of antibiotic dry suspensions reconstituted with various water temperatures. The testing included physical, microbial and chemical changes ... Read More
Trauma-induced Apoptosis of Endothelial Cells
Volume 2, Issue 3 , May and June 2019, , Pages 92-95
Abstract
Trauma is a common cause of death in developed countries leading trauma related coagulopathy. In recent years, ‘new type endothelium development’ caused by trauma-induced ... Read More
Assesment of Groundwater Samples from Sa'adatu Rimi College of Education, Kumbotso, Kano
Volume 2, Issue 3 , May and June 2019, , Pages 96-100
Abstract
Human activities are a major factor determining the quality of surface and groundwater through atmospheric pollution, effluent discharges, use of agricultural chemicals, eroded soil ... Read More
Ultrasound-assisted synthesis of auxiliary pyrazoline integrated thiazole, thiazolone derivative and their biological evaluation
Volume 2, Issue 3 , May and June 2019, , Pages 101-109
Abstract
In this paper, we describe a simplecatalyst-free protocol for the synthesis of thiazole, thiazolone integrated pyrazole derivatives, under ultra-sonication technique. Thiazolone derivatives ... Read More
A Journey Towards FeCl3 Catalysed Synthesis of Multisubstituted Pyrrole
Volume 2, Issue 3 , May and June 2019, , Pages 110-117