Journal of Medicinal and Chemical Sciences

Original Article

Synthesis, Characterisation, and Biological and Computational Studies of Novel Schiff Bases from Heterocyclic Molecules

Seta Azad Azad Aghaward; Layla Jasim Abbas; Kawkab Ali Hussein

Volume 6, Issue 8 , August 2023, Pages 1714-1726

https://doi.org/10.26655/JMCHEMSCI.2023.8.1

Abstract

Four new Triazole Schiff Bases were synthesized through the green condensation and were structurally confirmed by mass spectroscopy, IR, 1H NMR, TGA, and DSC. The chief advantages of ... Read More

Original Article

Impact of High Blood Pressure (HBP) on Health among Indian Stockholders

Tuhin Subhra Roy; B.Chandra Mohan Patnaik; Ipseeta Satpathy

Volume 6, Issue 8 , August 2023, Pages 1727-1736

https://doi.org/10.26655/JMCHEMSCI.2023.8.2

Abstract

HBP is the leading preventable cause of illness and premature death worldwide. It is easily diagnosed and can be controlled with relatively simple interventions. Yet, it is often unrecognized. ... Read More

Original Article

Expression of MicroRNA-155-5p in Chronic Kidney Disease as a Potential Marker of Cardiovascular Complications

Hend Sayed Mohamed; Alshaymaa M. Alhabibi; Ashraf Abd Elmaged Donia; Ghadir Mohamed Elsawy; Nehad Refaat Ibrahim; Mona A. Mohamed

Volume 6, Issue 8 , August 2023, Pages 1737-1745

https://doi.org/10.26655/JMCHEMSCI.2023.8.3

Abstract

Background: Chronic kidney disease (CKD) is a silent, serious condition requiring reliable non-invasive markers for diagnosing and predicting complications especially cardiovascular ... Read More

Original Article

Isolation and Characterization of Hyperoside-Flavanoidal Glycoside from Rourea Minor for its Anti-Hyperglycemic Activity Potential: An In Vitro Study

Kavya Yedelli; Ramachandran Kumar Pathangi

Volume 6, Issue 8 , August 2023, Pages 1746-1762

https://doi.org/10.26655/JMCHEMSCI.2023.8.4

Abstract

To investigate the anti-hyperglycemic activity potential of a hyperoside flavanoidal glycoside isolated from Rourea minor in vitro. The study design entails the preparation of Rourea ... Read More

Original Article

Oral Findings, Salivary Bicarbonate, and Phosphate Levels in Patients with Gastroesophageal Reflux Disease

Yousif Shaban Rajab; Taghreed Fadhil Zaidan

Volume 6, Issue 8 , August 2023, Pages 1763-1772

https://doi.org/10.26655/JMCHEMSCI.2023.8.5

Abstract

The neutralization of stomach's acidic contents and protection of esophageal mucous membrane during reflux episodes is the primary function of the major buffering components of saliva, ... Read More

Original Article

Potential of Bioactive Compound from Elephantopus scaber Linn. LEAF as Anti-Cancer Through in Silico Test

Yuliani Yuliani; Firas Khaleyla; Dwi Anggorowati Rahayu

Volume 6, Issue 8 , August 2023, Pages 1773-1782

https://doi.org/10.26655/JMCHEMSCI.2023.8.6

Abstract

Elephantopus scaber contains secondary metabolites, such as triterpenoids, sesquiterpene lactones, elephantopin, epifriedelinol, lupeol, stiqmasterol, lupeolacetate, deoxyelephantopin, ... Read More

Original Article

Ovarian Cancer (OC) Risk among Millennials in India

Ankita Nayak; Ipseeta Satpathy; B. Chandra Mohan Patnaik; Santosh Kumar Pani

Volume 6, Issue 8 , August 2023, Pages 1783-1798

https://doi.org/10.26655/JMCHEMSCI.2023.8.7

Abstract

The present study is an initiative to understand various related factors associated with ovarian cancer among millennials in India. The spark behind the present study after visiting ... Read More

Original Article

Safety and Efficacy of Popular Iranian Herbal Cold Remedy for COVID-19: A Randomized Clinical Trial in Mild to Moderate COVID-19 Cases

Samaneh Abiri; Alireza Hashemi Shiri; Mohammad Sadegh Sanie Jahromi; Esmaeil Rayatdoost; Hamid Afkhami; Ruhollah Ravanshad; Seyed Ehsan Hosseini; Navid Kalani; Parasta Heidari; Rahim Raoufi

Volume 6, Issue 8 , August 2023, Pages 1799-1809

https://doi.org/10.26655/JMCHEMSCI.2023.8.8

Abstract

Background: In traditional Persian medicine, an herbal cold remedy containing Sugarcane, Black Myrobalan, and mastic is mentioned and it was being widely provided by grocery stores. ... Read More Background: In traditional Persian medicine, an herbal cold remedy containing Sugarcane, Black Myrobalan, and mastic is mentioned and it was being widely provided by grocery stores. With the advent of the COVID-19 pandemic, the increased desire for this traditional remedy has led to a debate in society. Huge parts of the Iranian population have started using this remedy for the treatment of COVID-19; while no study has evaluated its efficiency and possible side effects. Thus, we aimed to evaluate the effects of Sugarcane, Black Myrobalan, and Mastic‏ ‏herbal medications for COVID-19 patients.Methods: This was a double-blinded randomized clinical trial study conducted over three months from May 2020 to July 2020 in SARS-COV2 PCR positive patients admitted in the COVID-19 ward of Peymaniyeh Hospital in Jahrom, Iran. Patients with severe COVID-19 infection were not recruited. The intervention group received the routine COVID-19 treatment protocol and the herbal supplement received the combination of black myrobalan and mastic and sugarcane, twice a day (3 g of herbal supplement). Study groups were compared in terms of demographic variables, vital signs, and clinical and laboratory variables for safety and efficiency assessment.Results: Seventy-two patients with COVID-19, divided into intervention (n=37) and control (n = 35) groups were studied. Intervention and control groups had not any significant difference in terms of baseline characteristics. The time-to-event analysis revealed a statistically significant difference in 4 symptoms of cough, fever, dyspnea, and myalgia (P<0.05). There was no significant difference in averaged O2 vital signs between the two groups (P>0.05). The Control group in comparison to the intervention group had a significantly lower decrease in C-reactive protein during 7 days (P<0.05). Patients in the herbal supplement group were hospitalized for 4.12 days and patients in the control group were hospitalized for 8.37 days (P=0.001). ICU admission and death only happened in 3 (8.6%) patients of the control group.Conclusion: This study showed that the proposed herbal remedy could be applied as supplementation to conventional management of COVID-19 patients with mild disease, while more research is needed for clinical application of this remedy.

Original Article

Synthesis of Dihydropyrimidinone (DHPM) Derivatives through a Multicomponent Reaction (MCR) and Their Biological Activity

Ahmad Fauzi; Azis Saifudin; Kamal Rullah

Volume 6, Issue 8 , August 2023, Pages 1810-1817

https://doi.org/10.26655/JMCHEMSCI.2023.8.9

Abstract

The spread of incurable diseases, especially infectious diseases caused by antibiotic-resistant bacteria and certain cancers, has become a serious public health concern. Consequently, ... Read More

Original Article

Electrochemical Polymerization of Eugenol and Corrosion Protection Studies of Stainless Steel 304L Alloy

Ayat Monther Alqudsi; Khulood Abed Saleh

Volume 6, Issue 8 , August 2023, Pages 1818-1829

https://doi.org/10.26655/JMCHEMSCI.2023.8.10

Abstract

This research includes the preparation of a poly-eugenol layer on the surface of a stainless steel electrode by electropolymerization process, where the polymer was diagnosed using ... Read More

Original Article

Relationship of Azoospermia Factor (AZF) and Inhibin B Level in Patients with Non-Obstructive Azoospermia

Ahmed Gamal El-Metwaly Ghanem; Mohamed Ali Atwa Barakat; Reham Mohammed El-Farahaty; Youssef Elbayoumi Youssef Soliman; Sohier Yahia; Hosam Abdel Twab

Volume 6, Issue 8 , August 2023, Pages 1830-1842

https://doi.org/10.26655/JMCHEMSCI.2023.8.11

Abstract

Background: Non-obstructive azoospermia (NOA) is a challenging subset in management of infertile males. Micro-deletion of the azoospermia factor (AZF) region located on long arm of ... Read More

Mini-Review Article

Mechanism of Immune System for Evading and Escaping Cancer Cells: A Brief Review

Ali Mohammed Abd AL-Ameer; Lubna Abdulazeem; Mazin H. Kzar; Essam Shawky Khattab; Ahmed Samir Naje

Volume 6, Issue 8 , August 2023, Pages 1843-1850

https://doi.org/10.26655/JMCHEMSCI.2023.8.12

Abstract

For everyone, at all ages, to live healthy lives and to promote well-being, there should be good health and welfare at every stage of one's life, beginning at birth, whereas health ... Read More

Original Article

Evaluating the Average Exposure Levels Provided to Neck and Cervical Spine CT Patients

Mysara Rumman; Khaled Sabarna; Jessica Badawi; Israa Bahar; Mohammad Darawai

Volume 6, Issue 8 , August 2023, Pages 1851-1861

https://doi.org/10.26655/JMCHEMSCI.2023.8.13

Abstract

To apply the radiation protection optimization concept, the current study compares the average doses utilized to produce the most popular CT scans of neck and cervical spine at the ... Read More

Original Article

Using Modified Resins in Chromium Ion Removal from Aqueous Solutions

Lubna Salah Muhammed; Hamsa Thamer Sadeq

Volume 6, Issue 8 , August 2023, Pages 1862-1871

https://doi.org/10.26655/JMCHEMSCI.2023.8.14

Abstract

Heavy metals are one of environmental concerns in industrial wastewater effluents, and adsorption is one of the widely used processes in removing heavy metals from aqueous solutions. ... Read More

Original Article

Effect of Different Plasma Concentrations Human Plasma and Goat Plasma on Human Blood Cell Growth In Vitro

Sada Jasim Abdulameer

Volume 6, Issue 8 , August 2023, Pages 1872-1877

https://doi.org/10.26655/JMCHEMSCI.2023.8.15

Abstract

Cultivated media for the growth of human blood cells are many, but the use of natural and less expensive materials is the most important to obtain the suitable growth for the cultivation ... Read More

Original Article

Use of Metal Frame Removable Partial Denture in Rheumatoid Arthritis: A Case Report

Michael Josef Kridanto Kamadjaja; Nike Puji Rahmawati; Wiwik Herawati Waluyo

Volume 6, Issue 8 , August 2023, Pages 1878-1884

https://doi.org/10.26655/JMCHEMSCI.2023.8.16

Abstract

Rheumatoid arthritis is an autoimmune disease that attacks the joints and causes complaints in the oral cavity, especially periodontitis. This study identified the case of a patient ... Read More

Original Article

Synthesis, Spectral, Cancer Inhibitory Activity and Antimicrobial Studies of Cobalt(II) and Nickel(II) Metal Complexes Containing Azo Derived from 2-Amino Benzimidazole

Neda Hasan; Muhammed Abdel Hasan Shallal; Hayfaa A. Mubarak; Mustafa M.Karhib; Ahmed S Naje

Volume 6, Issue 8 , August 2023, Pages 1885-1896

https://doi.org/10.26655/JMCHEMSCI.2023.8.17

Abstract

The production of the tridentate Azo ligand 2-[2/-(benzimidazolyl)azo]-4-bromo-6-chloro phenol (BIABrClP) complexes using Co(III) and Ni(II) is discussed in this article. Spectral methods ... Read More

Original Article

Sexually Transmitted Diseases (STDs) among Gen Y in India

Jagat Jyoti Amar Singh; Ipseeta Satpathy; B. Chandra Mohan Patnaik

Volume 6, Issue 8 , August 2023, Pages 1897-1908

https://doi.org/10.26655/JMCHEMSCI.2023.8.18

Abstract

Infections transmitted by sexual contact are known as sexually transmitted diseases (STDs). A significantly higher risk of STDs is associated with young Gen Y individuals than older ... Read More

Original Article

First Unprovoked Seizure in Indonesian Children

Prastiya Indra Gunawan; Riza Noviandi; Sunny Mariana Samosir

Volume 6, Issue 8 , August 2023, Pages 1909-1914

https://doi.org/10.26655/JMCHEMSCI.2023.8.19

Abstract

Introduction: First unprovoked seizure (FUS) in children is a frightening health problem that often to be taken to emergency room. EEG is absolutely required to determine seizure activity ... Read More

Original Article

Anti-Inflammatory Effect of Curcuma Longa on Ulcerative Colitis Caused via AcOH in Rats

Parvin Mahzouni; Salar Nasr Esfahani; Mohsen Minaiyan; Gholamreza Asghari; Mozhgan Saeidi

Volume 6, Issue 8 , August 2023, Pages 1915-1924

https://doi.org/10.26655/JMCHEMSCI.2023.8.20

Abstract

Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disorder of the small intestine and colon. The purpose of this research was to investigate the ... Read More

Scope of Nanotechnology in Cosmetics: Dermatology and Skin Care Products

Awais Hameed; Gull Rida Fatima; Kainat Malik; Ayesha Muqadas; M. Fazal-ur-Rehman

Volume 2, Issue 1 , January 2019, , Pages 9-16

https://doi.org/10.26655/jmchemsci.2019.6.2

Abstract

Women and men have been wearing cosmetics for centuries, although the styles have certainly undergone some dramatic changes over time. Cosmetics is a very vast field which has served ... Read More

Effect of Temperature of Water Used For Reconstitution On Stability Of Antibiotic Dry Suspension

Ebtihal Almadani Alforjany; Ruwida Mohamed Kamour

Volume 2, Issue 4 , July and August 2019, , Pages 177-183

https://doi.org/10.26655/jmchemsci.2019.8.8

Abstract

This study is carried out to test the stability of antibiotic dry suspensions reconstituted with various water temperatures. The testing included physical, microbial and chemical changes ... Read More

Primary Treatment of Landfill Leachate Effects on Heavy Metal and Soil Chemical Properties in Kwashe Industrial Area in Duhok Province, Kurdistan Region of Iraq

Najmaldin Ezaldin Hassan; Mustafa Ismail Umer

Volume 5, Issue 1 , January and February 2022, , Pages 1-9

https://doi.org/10.26655/JMCHEMSCI.2022.1.1

Abstract

Leachate is a major problem created from municipal solid waste (MSW) landfills and is considered the worst source of surface water and groundwater pollution. Kwashe industrial area ... Read More

A new flavonoid glycoside from Trichilia emetica

Abdullahi Usman; Vera Thoss; Mohammad Nur-e-Alam

Volume 2, Issue 4 , July and August 2019, , Pages 144-150

https://doi.org/10.26655/jmchemsci.2019.8.4

Abstract

A new compound, catechin-3-O-α-L-rhamnopyranosyl (1→4) β-D-glucopyranoside was isolated from the ethylacetate soluble fraction of the aqueous extract of the whole seeds ... Read More

Antimicrobial effects of Rosmarinus officinalis methanolic extract on Staphylococcus aureus, Bacillus cereus, Escherichia coli and Pseudomonas aeruginosa in laboratory conditions

Abolfazl Jafari-Sales; Parisa Hossein-Nezhad

Volume 3, Issue 2 , April 2020, , Pages 103-108

https://doi.org/10.26655/jmchemsci.2020.2.2

Abstract

Treatment of bacterial infections with chemicals has led to drug resistance. Therefore, research to replace herbal treatments with less side effects is of a great importance. Therefore, ... Read More

Original Article

Intensity Modulated Radiation and Volumetric Modulated Arc Therapies in Breast Cancer

May Z. Saddik; Fatiheea F. Hassan

Articles in Press, Accepted Manuscript, Available Online from 28 February 2023

https://doi.org/10.26655/JMCHEMSCI.2023.9.1

Abstract

Background: Breast cancer is the most common malignant neoplasm in women, accounting for 25% of all cancers. Radiotherapy is one of the safest methods compared with other treatments.Methods: ... Read More

Original Article

Clinical and Laboratory Characteristics of COVID-19 Patients with Fecal SARS-CoV-2 Detection at a Tertiary Hospital in Indonesia

Andrew Adhytia Lieputra; Rebriarina Hapsari; Cecilia Oktaria Permatadewi; Irfan Kesumayadi; Iva Puspitasari; Purnomo Hadi; Nur Farhanah; Hendro Wahyono; Hery Djagat Purnomo

Articles in Press, Accepted Manuscript, Available Online from 28 February 2023

https://doi.org/10.26655/JMCHEMSCI.2023.9.2

Abstract

Transmission prevention is important to prevent the spread of COVID-19. Although most cases are transmitted through droplets and aerosols, several studies have shown the possibility ... Read More

Original Article

Density Functional Theory, ADME, and Molecular Docking of Some Anthranilic Acid Derivatives as Cyclooxygenase Inhibitors

Karam S. Atrushi; Dana M. Ameen; Shaymaa H. Abdulrahman; Faris T. Abachi

Articles in Press, Accepted Manuscript, Available Online from 11 March 2023

https://doi.org/10.26655/JMCHEMSCI.2023.9.3

Abstract

Nonsteroidal anti-inflammatories (NSAIDs), are very effective agents in relieving mild to moderate pain and inflammation by inhibiting two isoforms of prostaglandin G-H synthetase (I ... Read More

Review Article

Perception of Patient Safety Incident Reporting System among Healthcare Workers in Palestinian Government Hospital

Salam Al Ratrout

Articles in Press, Accepted Manuscript, Available Online from 14 March 2023

https://doi.org/10.26655/JMCHEMSCI.2023.9.4

Abstract

The aim of the current study was to determine the system perception for reporting patient safety incidents among workers in the field of health care, evaluating the factors affecting ... Read More

Original Article

Communicable Diseases (CDs) Among Paramedics in Private Healthcare in India

Soumya Ranjan Ray Choudhury; B. Chandra Mohan Patnaik; Ipseeta Satpathy

Articles in Press, Accepted Manuscript, Available Online from 18 March 2023

https://doi.org/10.26655/JMCHEMSCI.2023.9.5

Abstract

Humanitarian emergencies including disasters associated with natural hazards, conflict, complex emergencies, and famines can pose significant risks to public health, especially when ... Read More

Original Article

Synthesis of Benzimidazole and Phthaloylamino Acid derivatives and Antibacterial Activity

Hussniya A. AlDifar; Basma S. Baaiu; Khalid M. A. Darwish; Mohamad F. Ali; Othman O. Dakhil; Mansour Abd-Alsalam; Haneen Al Difar

Articles in Press, Accepted Manuscript, Available Online from 18 March 2023

https://doi.org/10.26655/JMCHEMSCI.2023.9.6

Abstract

Seven novel benzimidazole and phthaloylamino acid derivatives were synthesized. In the presence of acetic acid, the phthalic anhydride reacted with benzidine in a cyclization reaction ... Read More

Original Article

Competitive Adsorption of Li+, Na+, and K+ Ions on Phillip Site/Chabazite Zeolitic Tuff from Jordan

Reem Naser Dabaibeh; Hiba Hamed Amayrah

Articles in Press, Accepted Manuscript, Available Online from 18 March 2023

https://doi.org/10.26655/JMCHEMSCI.2023.9.7

Abstract

The adsorption of alkali metal ions on zeolite has no such possibility of precipitation. In the current work, we have studied the adsorption isotherms, and the effect of pH and temperature ... Read More

Original Article

Critical Role of Monocyte Chemotactic Protein -1 and Macrophage Migration Inhibitory Factor in Children who Have Pneumonia

Gehad Nabil Abd El-Aal; Shimaa Moustafa Kamel; Mona Sayed Mohammad Attaya; Dalia Mahmoud Eldewi; Fatma Elzahraa AE. Diab; Marwa Mohsen Ramadan Hassan; Suzan Mohamed Abdel Kareem Mohamed

Articles in Press, Accepted Manuscript, Available Online from 20 March 2023

https://doi.org/10.26655/JMCHEMSCI.2023.9.8

Abstract

Background: The leading cause of death for children under the age of five years old worldwide is pneumonia. The assessment of illness progression and clinical stage is necessary for ... Read More

Original Article

Assessment of Salivary Alpha-Amylase, Cortisol, and Prevalence of Temporomandibular Disorder in Patients with Major Depressive Disorder

Ameer Ali Althabhawee; Taghreed Fadhil Zaidan Zaidan

Articles in Press, Accepted Manuscript, Available Online from 20 March 2023

https://doi.org/10.26655/JMCHEMSCI.2023.9.9

Abstract

There has been a general uptick in the number of people diagnosed with major depressive disorder (MDD) worldwide, which has led to a commensurate rise in the need for oral medicine ... Read More

Original Article

Predictors of Mortality in Sepsis Patients Resulting from Severe and Critical COVID-19

Nur Farhanah; Supriadi Supriadi; Hendro Wahjono; Suharyo Hadisaputro; Muhammad Hussein Gasem

Articles in Press, Accepted Manuscript, Available Online from 25 March 2023

Abstract

Patients with severe and critical COVID-19 may exhibit sepsis and mortality resulting from multi-organ failure. Neutrophil-lymphocyte-ratio (NLR) values, C-reactive protein (CRP) levels, ... Read More

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Facts & Figures
Journal date created	2018
Google Scholar h-index	16
Google Scholar i10-index	31
Google Scholar Citation	1094
WOS Citation	524
CiteScore 2021	0.8
CiteScore Tracker 2022	1.5
SJR 2021	0.203
SNIP 2021	0.272
Scopus Journal Rank (2021)	Q3
Impact Score	1.49
No. of volumes	6
No. of Issues	31
Number of articles	489
Review papers	16
No. of contributors	1,328
No. of submissions	998
Article view	252,453
View per article	516.26
PDF download	133,717
PDF Download Per Article	273.45
Rejected Submissions	414
Accepted Submissions	476
Acceptance Rate	48
Accept Date (Days)	44
No. of reviewers	8068
Contributing countries	36
No. of databases	9

Volume 6 (2023)

Volume 5 (2022)

Volume 4 (2021)

Volume 3 (2020)

Volume 2 (2019)

Volume 1 (2018)

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