A new flavonoid glycoside from Trichilia emetica

Document Type: Original Article

Authors

1 Department of Chemistry, Faculty of Natural and Applied Sciences, Nasarawa State University, P.M.B. 1022 Keffi, Nigeria

2 School of Chemistry, Bangor University, Bangor LL 57 2UW, United Kingdom

3 Department of Pharmacognosy, College of Pharmacy, King Saud University, P.O.Box 2457, Riyadh 11451, Saudi Arabia

Abstract

A new compound, catechin-3-O-α-L-rhamnopyranosyl (1→4) β-D-glucopyranoside was isolated from the ethylacetate soluble fraction of the aqueous extract of the whole seeds of Trichilia emetica (Family: Meliaceae). The structure of this compound was established on the basis of nuclear magnetic resonance (NMR), Infrared (IR) spectroscopy and ultraviolet-visible (UV-vis) spectrophotometry. The compound was also subjected to antimicrobial activity and brine shrimp lethality bioassay. The pure compound showed either no or reduced activity against microorganisms tested, it also showed no cytotoxicity.

Graphical Abstract

A new flavonoid glycoside from Trichilia emetica

Keywords

Main Subjects


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