Document Type: Original Article


School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China


A highly efficient and ligand-free approach for the Suzuki–Miyaura cross-coupling reaction of aryl halides with arylboronic acid catalyzed by CuI/Cs2CO3 in DMF has been developed. Under the described conditions, a category of aryl halides including iodides and bromides, whether electron-rich or electron-deficient, were coupled with arylboronic acid to give the target products (moderate to excellent yields). This catalytic system was less efficient in the reactions of aryl bromides as a higher reaction temperature was required to improve the yield.

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