QSAR Modeling, Molecular Docking, and ADME Studies of Novel 5-Oxo- Imidazoline Derivatives as Anti-Breast Cancer Drug Compounds against MCF-7 Cell Line
QSAR Modeling, Molecular Docking, and ADME Studies of Novel 5-Oxo- Imidazoline Derivatives as Anti-Breast Cancer Drug Compounds against MCF-7 Cell Line

Yellasubbaiah N; Velmurugan V

Volume 6, Issue 12 , December 2023, , Pages 3087-3112

https://doi.org/10.26655/JMCHEMSCI.2023.12.24

Abstract
  Thirty-six (36) new 5-oxo-imidazoline derivatives were studied using Insilco modeling against MCF-7 breast cancer cell lines. This research included QSAR, molecular docking, and pharmacokinetic ...  Read More
Expresion of Basic Fibroblast Growth Factor (bFGF) and Cell Apoptosis in Human Pterygium Fibroblast (HPF) after the Adminstration of Epigallocathecin-3-Gallate (EGCG) and Mitomycin-C (In Vitro Laboratory Experimental Study)
Expresion of Basic Fibroblast Growth Factor (bFGF) and Cell Apoptosis in Human Pterygium Fibroblast (HPF) after the Adminstration of Epigallocathecin-3-Gallate (EGCG) and Mitomycin-C (In Vitro Laboratory Experimental Study)

Astry Ayunda; Luki Indriaswati; Muhammad Firmansjah; Djoko Agus Purwanto; Budi Utomo

Volume 6, Issue 12 , December 2023, , Pages 3159-3166

https://doi.org/10.26655/JMCHEMSCI.2023.12.29

Abstract
  Pterygium is an ocular disease characterized by the growth of fibrovascular tissue and a wing-shaped fold of conjunctiva on the surface of the cornea. The progression of this disease ...  Read More
Synthesis and Biological Study of Some Transition Metal Ions Complexes of Schiff-Mannich Base Derived from 2- amino-5-mercpto -1,3,4 thiadiazole
Synthesis and Biological Study of Some Transition Metal Ions Complexes of Schiff-Mannich Base Derived from 2- amino-5-mercpto -1,3,4 thiadiazole

Wedad Hameed Majeed; Shaymaa R. Baqer; Sanaa A. Alsahib

Volume 6, Issue 4 , April 2023, , Pages 789-802

https://doi.org/10.26655/JMCHEMSCI.2023.4.10

Abstract
  Schiff –Mannich base derived from 1,3,4 thiadazole prepared by combining of 2-amino-5-mercapto-1,3,4 thiadazole and 4-N,N-dimethyl benzaldehyde with indol . The result compound ...  Read More
Design, Synthesis, Spectral Characterization, and Study of Biological Effect of Novel azobenzen-p,p'-di(2-amine-1,3,4-thiadiazol-5-yl) Derivatives
Design, Synthesis, Spectral Characterization, and Study of Biological Effect of Novel azobenzen-p,p'-di(2-amine-1,3,4-thiadiazol-5-yl) Derivatives

Zainab A. Jabarah; Amina A. Fayad; Israa Sh. A.R. Al- Kadi

Volume 6, Issue 4 , April 2023, , Pages 898-906

https://doi.org/10.26655/JMCHEMSCI.2023.4.22

Abstract
  The compound azobenzen-p,p'-di(2-amine-1,3,4-thiadiazol-5-yl) (A) was formed by reacting 4,4'-(diazene-1,2-diyl)-dibenzoyl chloride with thiosemicarbazide. Ten substituted amino derivatives ...  Read More