Document Type : Original Article


1 Department of Basic Science, University of Zalingei, Zalingei, Sudan

2 College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, P. R. China


Two new triterpenoid saponins, named, 3-O-β-D-glucopyranosyl (1→3)-Olean-12- ene- 19, 23-diol 1 and 3-O-{O-α-L-rhamno-pyranosyl-(1→3)-O-[-O-β-D-glucopyranosyl-(1→3)]-β-D-glucopyranosyl}-pomolic acid were isolated from the stem bark of Xeromphis nilotica through extensive chromatographic technique [TLC and CC] and their structures were elucidated on the basis of their spectral data [1D, 2D NMR and HR-ESI-MS] and chemical evidence.

Graphical Abstract

Triterpenoid Saponins from the Stem Bark of Xeromphis nilotica (Rubiaceae)



    1. Mariod,  A.Adam, S.I. Abdelwahab, S. Elkheir, Y.M. Ahmed, P.N.M. Fauzi, C.S.. Acta Scientiarum Polonorum Technologia Alimentaria. 2012, 11, 249-58.
    2.  A. Nabeil.  Antimicrobial, Doctoral dissertation, UOFK, 2015.
    3. B. Adzu. International Journal of Biological and Chemical Sciences, 2008, 2, 359-362.
    4. J. Fotie, D.S. Bohle,  M.L. Georges,  E. Leimanis, G. Rukunga,  A.E. Nkengfack.. Journal of Natural Products. 2006, 69, 62-67.
    5. 2. S. Margaret, Flowering plants in West Africa, Cambridge University Press, 1988.
    6. B. Adzu, M. B. Amizan, S. E. Okhale, J. Ethnopharmacology, 2014,158, 271.
    7. A. K. Bashir, Int. J. Pharmacognosy, 1996, 34, 202.
    8. H. A. R. Farid, O. Kuner, E. Haslinger, C. Seger, Monatshefte fur Chemie, 2002, 133, 1453.
    9. I. Hedberg, O. Hedberg, P. J. Madati, K. E. Mshigeni, E. N. Mshiu, G. Samuelsson, J. Ethnopharmacology, 1983,  9, 237.
    10. S. C. Chabra, R. L. A. Mahunnah, E. N. Mshiu, J. Ethnopharmcology, 1991, 33, 143.
    11. I. Abdurrahman, Y. C. Xia, H. Y. Lai, WJPR, 2016, 15, 292-300.
    12. H. Jeffrey, Phytochemical methods a guide to modern techniques of plant analysis, Springer Science and Business Media, 1998.
    13. A. A. Magid, L. V. Nazabadioko, I. Renimel, D. Harakat, C. Moretti, C. Lavaud, Phytochemistry, 2006, 67, 2098.
    14. M. A. Ouyang, Y. Q. Liu, H. Q. Wang, C. R. Yang, Phytochemistry, 1998,  49, 2485.
    15. J. Li, X. Huang, X. H. Jiang, Q. F. Zhu, Y. Yang, G. C. Gao, Chem. Pharm. Bull., 2015, 63, 389.