Journal of Medicinal and Chemical Sciences

Review Article

Watermelon Allsweet: A Promising Natural Source of Bioactive Products

Rahma Mowaffaq Jebir; Yasser Fakri Mustafa

Volume 5, Issue 5 , September and October 2022, Pages 652-666

https://doi.org/10.26655/JMCHEMSCI.2022.5.1

Abstract

Watermelon is a nutrient-dense fruit, contrary to the popular assumption that it is primarily composed of water and sugar. Watermelon, the whole fruit, is distinguished by a variety ... Read More

Original Article

Asthma Recurrent in Children: Parental Knowledge Along with Medical Treatment

. Irdawati; Mutia Chandra Permata Sury

Volume 5, Issue 5 , September and October 2022, Pages 667-675

https://doi.org/10.26655/JMCHEMSCI.2022.5.2

Abstract

Children, like adults, are not immune to asthma and may develop the disease. Obviously, children face specific challenges and difficulties that can cause shortness of breath and disruption ... Read More

Review Article

A Review of Classical and Advanced Methodologies for Benzocoumarin Synthesis

Sara Firas Jasim; Yasser Fakri Mustafa

Volume 5, Issue 5 , September and October 2022, Pages 676-694

https://doi.org/10.26655/JMCHEMSCI.2022.5.3

Abstract

Coumarins belong to a worthwhile family of heterocycles that exist naturally and/or synthetically. Benzocoumarins are a type of extended structure of coumarins in which the coumarin ... Read More

Review Article

A Review on Dental Material with Regard to Biocompatibility Properties

Noor Hafida Widyastuti; Aulia Rizky Nurwita

Volume 5, Issue 5 , September and October 2022, Pages 695-702

https://doi.org/10.26655/JMCHEMSCI.2022.5.4

Abstract

The use of dental materials in the human mouth is not possible except by relying on physiological, biological, pathological studies and the study of physical, mechanical, and chemical ... Read More

Review Article

Benzocoumarin Backbone Is a Multifunctional and Affordable Scaffold with a Vast Scope of Biological Activities

Sarah Ahmed Waheed; Yasser Fakri Mustafa

Volume 5, Issue 5 , September and October 2022, Pages 703-721

https://doi.org/10.26655/JMCHEMSCI.2022.5.5

Abstract

Coumarins having an aryl phenol linked to the 3,4-, 5,6-, 6,7-, or 7,8-binding sites are referred to as benzocoumarins. Efforts have been made in recent years to separate new configurations ... Read More

Original Article

Work Life Balance of Health Care Workers during COVID-19 in India

Tapaswini Pattnaik; Sasmita Rani Samanta; Jitendra Mohanty

Volume 5, Issue 5 , September and October 2022, Pages 722-733

https://doi.org/10.26655/JMCHEMSCI.2022.5.6

Abstract

The term work–life balance is a blend of two words, work and life. In the context of the extant research, the focus is on the health care workers, who are the front-line warriors ... Read More The term work–life balance is a blend of two words, work and life. In the context of the extant research, the focus is on the health care workers, who are the front-line warriors during the Covid-19 pandemic. They include amongst others doctors, nurses and health care administrators. The contributions of these front-line workers during this pandemic are invaluable. However, they have to face the brunt of the pandemic which affected work life balance enormously. In this background, the present paper is an initiative to understand the various dynamics related to the work life balance of health care workers, particularly during the pandemic, and for this purpose four leading hospitals in the study area were selected for collection of data. The entire data were analyzed under four parameters, work pressure related issues, infrastructure and family issues, organizational policy, and work related cash and non-cash benefits. Overall, twenty two hypotheses were developed and out of these seven null hypotheses and fifteen alternative hypotheses were accepted. As regards to the work pressure related issues three null and three alternative hypotheses were developed, whereas basing on infrastructure and family issues one null and three alternate hypotheses were accepted. On the basis of organization policies, seven hypotheses were developed and all of them were accepted as all alternative hypotheses and similarly, out of five hypotheses related to cash and non-cash benefits, three null and two alternative hypotheses were accepted. Concerns and difficulties in the workplace and personal problems in life affect each other. The equilibrium of work-life is conceived as a dual system that gives fair weightage to the demands of both the employees and employers. There cannot be an equal balance between work and life, rather, it is a matter of prioritizing and managing the burden of each field in order to align time, energy, and resources so that work and life are satisfied. The present paper is an endeavor to decode the various issues related to work life balance of health care workers in the new normal. The paper is hoped to be an additional contribution to the existing literature.

Original Article

Intensive Care Unit of COVID-19 during the Different Waves of Outbreaks in Jahrom, South of Iran

Mohammad Sadegh Sanie Jahromi; Khadijeh Aghaei; Lohrasb Taheri; Navid Kalani; Naser Hatami; Zhila Rahmanian

Volume 5, Issue 5 , September and October 2022, Pages 734-742

https://doi.org/10.26655/JMCHEMSCI.2022.5.7

Abstract

Introduction: The apt description of COVID-19’s clinical course throughout hospitalization provides experiences for dealing with subsequent outbreaks, especially in patients with ... Read More

Original Article

Comparison Study of Cloud Point and Solvent Extraction of Copper by 3-Chloro-2,4-pentanedione as Complexing Agent

Azhar Hameed Gatea; Saher A. Ali Alshamkhawy; Wathiq Sattar Abdul-hassan

Volume 5, Issue 5 , September and October 2022, Pages 743-752

https://doi.org/10.26655/JMCHEMSCI.2022.5.8

Abstract

This study reports a comparison between two types of extraction. The first one is traditional extraction which can be called liquid-liquid extraction (LLE) or solvent extraction, while ... Read More

Original Article

Surveillance of Multidrug-resistant Iraqibacter Isolated from Patients with Urinary Tract Infection at a Baghdad Urology Center

Sinan Bahjat Alrifai; Wakas Saadi Mahmood; Noor Hamdi Jasem

Volume 5, Issue 5 , September and October 2022, Pages 753-759

https://doi.org/10.26655/JMCHEMSCI.2022.5.9

Abstract

Background: We dealt with Multidrug- resistant Acinetobacter baumanniiisa “red alert” pathogen that is included in the acronym “ESKAPE” along with other five ... Read More

Original Article

Preparation and Evaluation of Etodolac Nanoemulsion

Ahmed H. Hussein; Walla Mohamad; Ahmed D. Abid Muslim; Ali I. Salman; Mohannad F. Abdu Al-Hussein; Ameer M. Muhammad; Zharaa A. Hassan

Volume 5, Issue 5 , September and October 2022, Pages 760-768

https://doi.org/10.26655/JMCHEMSCI.2022.5.10

Abstract

Emulsions could be defined as heterogeneous system thermo-dynamically unstable of a two-phase system consisting of at least two immiscible liquids. A third component, the emulsifying ... Read More Emulsions could be defined as heterogeneous system thermo-dynamically unstable of a two-phase system consisting of at least two immiscible liquids. A third component, the emulsifying agent, is necessary to stabilize the emulsion. Etodolac is used to relieve pain, swelling, and joint stiffness from arthritis. The local administration of the drug topically will avoid the systemic side effects besides some advantages making it a superior dosage form. The present study aims to formulate and evaluate nanoemulsion composed of different oils and surfactant system systems and find the best microemulsion formula in terms of particle size and stability. The present study includes making different emulsion formulas and implementing etodolac into them. The formulas were made by wet gum using DW, oils (almond and eucalyptus), and surfactants (tweens, span, and triton X). Experiments were then done on the formulas to choose successful ones to put etodolac into. One of the successful formulas had etodolac implemented into them and further experiment were done after. Finally, etodolac was tested in-vivo in the form of cream to see its efficacy by a pharmacologist.Results revealed that all prepared formulas succeeded in giving emulsion but with variable degree of properties and stability. Their pH are acidic with no sensitization to skin. Selected formula Fe2 contains eucalyptus oil and a mixture of tween40 and triton x is the best formula in terms of stability, reliability, and globular size. Upon addition of etodolac drug formula still stable and globular size is small and uniform under laser diffraction analyzer. Eucalyptus and almond oils can give stable emulsion. Oil in water emulsion type is predominant in all prepared formulas. A stable and promising formula was obtained with no sensitization was seen, and this formula is ready to be applied to human skin after some more tests to be marketed as microemulsion formula for the analgesic drug etodolac.

Original Article

Anticandidosic Activity and Acute Toxicity of Quercus Suber L. Bark Extracts

Qamar Lahlimi-Alami; Rajaa Layachi; Rachida Hassikou; Jalila Benjelloun; Lamiae Amallah; Naima Guennoun; Younes Zaid; Sarah Bouzroud

Volume 5, Issue 5 , September and October 2022, Pages 769-778

https://doi.org/10.26655/JMCHEMSCI.2022.5.11

Abstract

The cork oak (Quercus suber L.) is commonly used in traditional pharmacopoeia. The main objective of this work is to contribute to the valorization of this plant species through the ... Read More

Original Article

Disturbances of Lipid Profile, Hemoglobin and Serum Ferritin Levels in Thalassemia Patients in Misan City, Amara, Iraq

Eman Khammas AlSaadi

Volume 5, Issue 5 , September and October 2022, Pages 779-786

https://doi.org/10.26655/JMCHEMSCI.2022.5.12

Abstract

Background: One of the most common hereditary hematological disorders is beta thalassemia major manifested by severe hemolysis and profound anemia for which the regular blood transfusions ... Read More Background: One of the most common hereditary hematological disorders is beta thalassemia major manifested by severe hemolysis and profound anemia for which the regular blood transfusions are required that leading to the iron accumulation in blood and body organs as well as increased serum ferritin. Thalassemic patient’s lipid profile levels are significantly variable in many studies.Aims: The study aimed to detect any alteration of serum lipid profiles in thalassemic major patients and to find out if they are correlated with serum ferritin and Hb concentration.Method sand patients: Sixty-two Beta thalassemia major patients were enrolled in the study, aged (6months-15 years) randomly selected (65) matched control children. Obtaining serum samples for lipid profile, and ferritin estimation, as well as blood test of hemoglobin concentration was done. Statistical data analysis was performed using standard methods.Results: The most presented age was (>5-10 years.) followed by (6mo-5years) then (>11-15 years.) (27, 21, 14) patients, respectively. Female were slightly predominant than male (54.8%), (45.2%), respectively mainly in group 2 (55.9%), while male slightly predominates in the younger and older groups (26.5%), (17.7%), respectively. Serum ferritin levels were very high in (98.4%) of cases, mainly in group 2 (43%), then in group 1 (34%), followed by group 3 (23%). The majority of patients had normal cholesterol level (95.16%). Lipoprotein were Low in (35.5%) of patients mainly in group 2 (54.5%) and normal in (64.5%) mainly equally distributed in groups, although not statistically significant, (p.value=0.7). Low Density Lipoprotein was normal in most patients (95.16%), and not significant statistically (P value=0.8). Triglyceride was high in most patients (83.9%), while normal in (16.1%), it was with no statistically significant (p. value=0.4).Conclusion: The present study concluded a positive correlation between (high Triglyceride, low, and high density Lipoprotein) and (low Hb and high ferritin levels) which may attribute to the future fatal cardiac complication.

Original Article

Dysmenorrhea among Female University Students during the COVID-19 Pandemic

Ekhlas Ali Hussein; Israa Talib Hassan; Hala Saadi Issa; Mahasen M. Abd Al-Majeed

Volume 5, Issue 5 , September and October 2022, Pages 787-792

https://doi.org/10.26655/JMCHEMSCI.2022.5.13

Abstract

Dysmenorrhea is the most common gynecological symptom among adolescent girls and young women. It can have a significant impact on females’ quality of life. The study aims to investigate ... Read More

Original Article

Synthesis, ADME Study, and Antimicrobial Evaluation of Novel Naphthalene-Based Derivatives

Sara Firas Firas Jasim; Yasser Fakri Mustafa

Volume 5, Issue 5 , September and October 2022, Pages 793-807

https://doi.org/10.26655/JMCHEMSCI.2022.5.14

Abstract

In recent times, many researchers in pharmaceutical chemistry have been preoccupied with the quest for new potent anti-infective agents to combat antimicrobial resistance. A novel series ... Read More

Original Article

Synthesis and Evaluation of New Coumarins as Antitumor and Antioxidant Applicants

Sarah Ahmed Waheed; Yasser Fakri Mustafa

Volume 5, Issue 5 , September and October 2022, Pages 808-819

https://doi.org/10.26655/JMCHEMSCI.2022.5.15

Abstract

This work involves the synthesis of eight novel fused coumarin compounds, which were confirmed by various spectrophotometers and then, assessed for their apoptotic-inducing and free ... Read More

Review Article

Burnout in Hospital and Pre-Hospital Emergency Departments: A Systematic Review Study

Ali Ravaghi; Roohie Farzaneh; Farhad Bagherian; Arman Hakemi; Ghazal Seghatoleslami; Samaneh Abiri; Hossein Hakimelahi; Fatemeh Maleki

Volume 5, Issue 5 , September and October 2022, Pages 820-830

https://doi.org/10.26655/JMCHEMSCI.2022.5.16

Abstract

Introduction: Hospital and Pre-hospital emergency staff are the first to experience stressful situations, and this long-term stress leads to burnout. This study aimed to investigate ... Read More

Original Article

Natural Products Catalog of Allsweet Watermelon Seeds and Evaluation of Their Novel Coumarins as Antimicrobial Candidates

Rahma Mowaffaq Jebir; Yasser Fakri Mustafa

Volume 5, Issue 5 , September and October 2022, Pages 831-847

https://doi.org/10.26655/JMCHEMSCI.2022.5.17

Abstract

The infections resistant to the current antimicrobials are becoming more prevalent today. So, in an attempt to discover the novel pharmacologically active scaffolding for the development ... Read More

Original Article

Analyzing the Relationship between Obstetric Characteristics with Antenatal Depression

Yuli Kusumawati; Dinda Anindita Salsabila; Widyawati Widyawati; Fatwa Sari Tetra Dewi

Volume 5, Issue 5 , September and October 2022, Pages 848-856

https://doi.org/10.26655/JMCHEMSCI.2022.5.18

Abstract

The current study investigated the impact of growth hormone (GH) and polymorphism of calpain genes (CAPN1) on the changes in live weight and qualitative and quantitative indicators ... Read More

Review Article

Children with Disabilities: A Review on Medical Care and Social Supports

Krutykh Elena Valeryevna; Hakuz Pshimaf Muratovich1; Kabanov Oleg Vladimirovich; Pisklova Marina Vitalevna Vitalevna; Zhirkova Zoya Semyonovna; Maltseva Alina Aleksandrovna; Sapozhnikova Nadezhda Ivanovna

Volume 5, Issue 5 , September and October 2022, Pages 857-865

https://doi.org/10.26655/JMCHEMSCI.2022.5.19

Abstract

Type 1 diabetes is one of the most common chronic diseases in children. The cause of this disease is the destruction of pancreatic beta cells and the consequent loss of insulin production ... Read More

Case Report

Depression and Anxiety as Mental Health Disorders That Affect Pregnancy: A Case Study in Surakarta, Indonesia

Yuli Kusumawati; Dinda Anindita Salsabila; Widyawati Widyawati; Fatwa Sari Tetra Dewi

Volume 5, Issue 5 , September and October 2022, Pages 866-873

https://doi.org/10.26655/JMCHEMSCI.2022.5.20

Abstract

Obstetric characteristics of pregnancy and the reproductive process are related to the susceptibility of pregnant women to mental health problems. This study aims to analyze the relationship ... Read More

Volume 6 (2023)

Volume 5 (2022)

Volume 4 (2021)

Volume 3 (2020)

Volume 2 (2019)

Volume 1 (2018)

Volume & Issue: Volume 5, Issue 5, September and October 2022, Pages 652-873

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