Document Type : Original Article
Authors
1 Organic Chemistry Laboratory (LCO), Faculty of Sciences Dhar El Mahraz–Sidi Mohammed Ben Abdellah University, Fez 30000, Morocco
2 Biotechnology Laboratory, Faculty of Sciences Dhar El Mahraz–Sidi Mohammed Ben Abdellah University, Fez 30000, Morocco
Abstract
The compounds used in this study, TET and OXM, were tested in vitro for their antibacterial activities against isolated strains from the hospital environment (S. aureus H, E. coli H and K. pneumoniae H) and reference strains (S. aureus A, E. coli A, B. subtilis A and P. aeruginosa A). The calculation of the MBC/minimum inhibitory concentration ratio of the products TET and OXM showed that the two products have a bactericidal effect on the strains tested.
Graphical Abstract
Keywords
2. H. Bekkari, H. Touijer, S. Berrada, M. Ettaybi, N. Benchemsi, S. Maniar, A.E.Q. Lalami, J. Mater. Environ. Sci.; 2016, 7, 1.
3. L. Bergeron, S. Carle, M.C. Michel, D. Thirion, Pharmactuel. 2009, 42, 22.
4. J.P. Lavigne, 2007. Effet des antibiotiques et mécanismes de résistance. cours de bactériologie. Faculté de Médecine Montpellier-Nimes.
5. M.B. Said, A.M. Mohamed, R.M. Azza, H.A. Mohamed, J. Am. Sci. 2016, 12, 40.
6. A.E.Q. Lalami, F. El-Akhal, B. Oumokhtar, Inter. J. Pharm. Clin. Res. 2016, 8, 537.
7. V. Dhayanithi, S. Shafi Syed, K. Kumaran, K.R. Jai Sankar, R. Venkat Ragavan, P.S. Kumar Goud, N.S. Kumari, H.N. Pati, J. Serb. Chem. Soc. 2011, 76, 165.
8. S.N. Rao, T. Ravisankar, J. Latha, K. Sudhakar Babu, Der Pharma Chemica. 2012, 4, 1093.
9. G.M.M. Sampaio, A.M.R. Teixeira, H.D.M. Coutinho, D.M. Sena Junior, P.T. Freire, R.R.F. Bento, L.E. Silva, EXCLI Journal. 2014, 13, 1022.
10. D.F.J. Brown, M. Wootton, R.A. Howe, J. Antimicrob. Chemother. 2016, 71, 3.
11. P. Melvin, M.D. Weinstein, Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically, 11th Edition, 2018, 1-112.
12. C.M. Mann, J.L. Markham, J. Appl. Microbiol. 1998, 84, 538.
13. A. Hellal, S. Chafaa, N. Chafai, Inter. J. Sci. Eng. Res. 2015, 6, 1622.
14. C. Delarras, Microbiologie. 90 heures de travaux pratiques. Gaétan Morien Editeur, 1998, 169-178.
15. H.A. Khan, A. Ahmad, R. Mehboob, Asian. Pac. J. Trop. Biomed. 2015, 5, 509.
16. D. Gatsing, V. Tchakoute, D. Ngamga, J.K. Kuiate, J.D.D. Tamokou, Iran. J. Med. Sci. 2009, 34, 126.