Journal of Medicinal and Chemical Sciences

Synthesis and Characterization with Antimicrobial Studies of mixed Curcumin Schiff Base –L-dopa with Divalent Cations Complexes

Hala Mohammed Salh; Taghreed H Al-Noor

Volume 6, Issue 7 , July 2023, , Pages 1621-1630

https://doi.org/10.26655/JMCHEMSCI.2023.7.13

Abstract

In the present article, mixed ligand metal (II) complexes have been synthesized with Schiff base (1E, 5Z, 6E)-1,7 bis (4-hydroxy-3-methoxyphenyl)-5-(3-hydroxyphenyl) imino) hepta-1,6-dien-3-one ... Read More

Activity of Silybum marianum in Oral Candidiasis of Albino Rats

Zahraa Sedeeq Qasim; Zahraa Amer Hashim

Volume 6, Issue 5 , May 2023, , Pages 976-985

https://doi.org/10.26655/JMCHEMSCI.2023.5.5

Abstract

Silybum marianum is a primitive compound mixture that has pharmaceutical and pharmacological activities. Studies have highlighted the role of Silybum marianum in treating candidiasis. ... Read More

Synthesis and Identification of Some Metal Complexes Derived from Azo Ligand of 4,4'-Methylenedianiline and 4-Bromoaniline and Antimicrobial Studies

Lina Saadi; Saba A. Ali; Azhar A. Ghali

Volume 6, Issue 4 , April 2023, , Pages 720-732

https://doi.org/10.26655/JMCHEMSCI.2023.4.3

Abstract

The new diazo ligand, and its complexes with metals ions Cu(II), Zn(II), Cd(II), and Ag(I), were synthesized, and ligand synthesis was done via diazotization of 4,4'-Methylenedianiline ... Read More

Isolation, Screening, and Identification of Local Bacterial Isolates Producing Bio-Cellulose

Tayseer Shamran Al-Deresawi; Melad Khalaf Mohammed; Saad Hussein Khudhair

Volume 6, Issue 3 , March 2023, , Pages 622-633

https://doi.org/10.26655/JMCHEMSCI.2023.3.19

Abstract

The current study aims to easily, quickly, and cheaply select the local bacterial isolate that produces bacterial cellulose. Ten samples of spoiled fruits (triplicate for each) were ... Read More The current study aims to easily, quickly, and cheaply select the local bacterial isolate that produces bacterial cellulose. Ten samples of spoiled fruits (triplicate for each) were taken in Al-Kut City/ Wasit Province/ Iraq. A modified H-S medium was used to isolate the local bacteria from spoiled fruit samples. One-hundred and twelve bacterial isolates were obtained from all samples, where the lemon sample give the highest number of isolates, as it reached 20 isolates, while the banana sample gives the lowest number of isolates reached to 6 isolates. The two steps of screening were achieved to select the best cellulose-producing local isolate, results from the primary screening indicated that only 18 isolates appeared a clear ability to create clear zones as an indicator to produce bacterial cellulose, and the isolates TELE8, TELE11, TEKI4, and TEAP5 gave the highest clear zones of 7.5, 6.1, 6.2, and 6.5 cm, respectively. Also, the second screening step confirmed the results collected from the first step, as the results hydrogel test indicated that only 18 strains showed the ability to produce bacterial cellulose, while the other isolates were unable to do so, as the results showed that the isolate TELE8 was superior in its ability to produce bacterial cellulose than isolates TEK11, TEKI4, and TEAP5. Therefore, the local isolate TELE8 was chosen as the best isolate that produces bacterial cellulose. Thereafter, the phenotype and genotype characteristics were used to identify the TELE8 isolate; its results indicated that the isolate belongs to Komagataeibacter xylinum (previously named first Acetobacter xylinum, and then Gluconacetobacter xylinus). The three methods (static, shaker, and fermenter) were used to produce the bacterial cellulose by using the best local bacterial isolate Acetobacter xylinum TELE8 in HS medium. The results revealed that the highest production of BC (22.8 g/200 ml medium) was obtained when using the fermenter method, while the shaker method did not give the productivity of bacterial cellulose.

Inhibitory Effects of Administration of Curcumin Against on Streptococcus Mutans: In vitro and In vivo Studies

Ilia Asadi; Mojtaba Pakravan; Khashayar Bahramsari; Mahsa Rekabi; Nasroallah Moradi-kor; Elham Sadat Afraz

Volume 5, Issue 3 , May and June 2022, , Pages 436-441

https://doi.org/10.26655/JMCHEMSCI.2022.3.19

Abstract

Streptococcus mutans is a harmful bacterium that destroys teeth and increases the development of caries. The use of a safe antibacterial compound can decrease the population of S. mutans ... Read More

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Main Subjects = Antimicrobial agents

Synthesis and Characterization with Antimicrobial Studies of mixed Curcumin Schiff Base –L-dopa with Divalent Cations Complexes

Abstract

Activity of Silybum marianum in Oral Candidiasis of Albino Rats

Abstract

Synthesis and Identification of Some Metal Complexes Derived from Azo Ligand of 4,4'-Methylenedianiline and 4-Bromoaniline and Antimicrobial Studies

Abstract

Isolation, Screening, and Identification of Local Bacterial Isolates Producing Bio-Cellulose

Abstract

Inhibitory Effects of Administration of Curcumin Against on Streptococcus Mutans: In vitro and In vivo Studies

Abstract