Adil Turki Al-Musawi; Sudad Jasim Mohammed; Aliaa Saadoon Abdul-Razzaq
Abstract
This research aimed to evaluate the impact of Artemisia annua L. (A. annua L.) on liver and kidney functions following lead-induced injury that was extracted from the plant by using ...
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This research aimed to evaluate the impact of Artemisia annua L. (A. annua L.) on liver and kidney functions following lead-induced injury that was extracted from the plant by using ethanol. Forty male rats were divided into 4 classes (ten rats per group), G1 called negative regulation, G2 administered 15 mg/kg of lead acetate per day for 15 days orally, G3 administered A. annua L. extract at 100 mg/ml IP for 2 weeks, and G4 administered 15 mg/kg of lead acetate per day for 15 days, and then handled A. annua L. at (100 mg/kg b.wt) for two weeks. As a result of the procedure, blood samples were aspirated for serum isolation, the serum was used to estimate alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatinine, and Urea. The present findings showed a significant (P≤0.05) increase in levels of AST and ALT in G2 compared with G1 and G3 which showed normal values, while G4 showed a significant decrease in ALT and AST levels as compared with G1 and G3, whereas G4 displayed a significant (P≤0.05) reduction popular levels of urea, creatinine G 2 related to G1 and G3 which revealed normal values.