Journal of Medicinal and Chemical Sciences

Effect of Oral Clonidine as a Premedication on Hemorrhage during Septorhinoplasty: A Double-Blind Randomized Clinical Trial

Mojtaba Sohrabpour; Seyed Ebrahim Sadeghi; Mojtaba Ghaedi; Navid Kalani; Mohammad Sadegh Sanie Jahromi

Volume 5, Issue 6 , November and December 2022, , Pages 1001-1007

http://dx.doi.org/10.26655/JMCHEMSCI.2022.6.13

Abstract

Introduction: Intraoperative hemorrhage is one of the most important complications of septorhinoplasty surgery. Many techniques and drugs are used to reduce this problem. Accordingly, ... Read More

A Comparative Study on the Effects of Propofol and Thiopental on the Apgar score of Neonates Undergoing Cesarean Section under General Anesthesia: A Systematic Review Study

Seyed Ebrahim Sadeghi; Mehrdad Malekshoar; Majid Vatankhah; Pourya Adibi; Elham Rahmanian; Mohammad Sadegh Sanie Jahromi; Maryam Nemati

Volume 5, Issue 6 , November and December 2022, , Pages 1008-1017

http://dx.doi.org/10.26655/JMCHEMSCI.2022.6.14

Abstract

Introduction: Apgar score of neonates at birth is one of the determinants of postnatal mortality and one of the effective factors in Apgar score of cesarean section neonates that is ... Read More Introduction: Apgar score of neonates at birth is one of the determinants of postnatal mortality and one of the effective factors in Apgar score of cesarean section neonates that is the type of drug used for maternal anesthesia. Owing to the disagreement on the benefits and possible side effects of anesthetics, the present study was an attempt to evaluate and compare the effects of propofol and thiopental on the Apgar score of neonates undergoing cesarean section under the general anesthesia.Methods: The present study is a systematic review. Persian articles were searched in databases such as SID, Iranmedex, Magiran, and English articles were searched in databases such as Science Direct, PubMed, ProQuest, Cochrane Library, Embase, Scopus, and Google Scholar search engine without any time limitation. To access the full text of articles, the keywords of propofol, thiopental, general anesthesia, neonatal Apgar score, cesarean section, and their combination, the Boolean search methods, and conjunctions of “And” and “Or” were used. The information of reviewed articles included the first author, year of publication, the country of study, the sample size, and the outcome of the study.Results: A total of 27 articles were included to the study. In 22 studies, no statistically significant difference was found between thiopental and propofol effects on neonatal Apgar score at minutes 1 and 5. Also, in 4 studies, Apgar scores at minutes 1 and 5 were reported higher in the propofol group than the thiopental group. Furthermore, in one study, Apgar score at minute 1 was reported higher in the propofol group than the thiopental group. In three studies, Apgar score of neonates at the minute 1 in thiopental group was reported higher than the propofol group.Conclusion: It seems that neonates whose mothers underwent the general anesthesia with propofol for cesarean section have better Apgar scores than those who received thiopental. One of the effects of propofol is its shorter duration of action, and if the patient has a problem with difficult intubation, the effect of the drug ends sooner and the patient’s breathe returns as soon as possible. Likewise in this regard, compared to thiopental, which has a longer effect, Propofol is a more effective drug in cesarean section women under the general anesthesia.

Investigating the Effect of Oral Clonidine on Surgeon Satisfaction from Surgical Field in Septorhinoplasty

Mojtaba Ghaedi; Lohrasb Taheri; Mojtaba Sohrabpour; Navid Kalani; Mohammad Sadegh Sanie Jahromi

Volume 5, Issue 6 , November and December 2022, , Pages 1085-1093

http://dx.doi.org/10.26655/JMCHEMSCI.2022.6.21

Abstract

Introduction: Haemorrhage during septorhinoplasty surgery is challenging for the surgeons since it can reduce the visibility of the surgical site. Thus, the present study aimed to investigate ... Read More

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Author = Mohammad Sadegh Sanie Jahromi

Effect of Oral Clonidine as a Premedication on Hemorrhage during Septorhinoplasty: A Double-Blind Randomized Clinical Trial

Abstract

A Comparative Study on the Effects of Propofol and Thiopental on the Apgar score of Neonates Undergoing Cesarean Section under General Anesthesia: A Systematic Review Study

Abstract

Investigating the Effect of Oral Clonidine on Surgeon Satisfaction from Surgical Field in Septorhinoplasty

Abstract