TY - JOUR ID - 143662 TI - Influence of albocarbon-cyclic hybridization on biomedical activities: A review JO - Journal of Medicinal and Chemical Sciences JA - JMCS LA - en SN - AU - Mustafa, Yasser Fakri AU - Bashir, Moath Kahtan AU - Oglah, Mahmood Khudhayer AD - Department of Pharmaceutical Chemistry, College of Pharmacy, University of Mosul, Ninavah-41002, Iraq Y1 - 2022 PY - 2022 VL - 5 IS - 4 SP - 518 EP - 536 KW - Albocarbon KW - Hybridization KW - Cyclic moieties KW - Pharmacological activities DO - 10.26655/JMCHEMSCI.2022.4.8 N2 - There is an excellent demand in biomedical sciences for novel drug-like compounds with the best therapeutic benefits and minor adverse effects. The albocarbon moiety is seen to be abundantly available in nature, prompting various investigations to isolate albocarbons and investigate their pharmacological activities. Synthetic albocarbons show various biological properties, including antioxidant, antibacterial, antiproliferative, anti-inflammatory, antifungal, and antiviral effects. The consequences of hybridizing cyclic molecules with albocarbons on their bioactivities have been studied widely in the literature. The bulk of these studies revealed that this hybridization might improve the pharmacological properties of the mother albocarbons. This comprehensive review, which described the most critical and recent examples of such studies, emphasized the structural features of the produced hybrids as potentially bioactive frameworks. UR - https://www.jmchemsci.com/article_143662.html L1 - https://www.jmchemsci.com/article_143662_36a6346f1e8797d2b412a22c9f15d724.pdf ER -