TY - JOUR ID - 143142 TI - Medical and Pharmacological Evaluation of Scar Formation in Plastic Surgery JO - Journal of Medicinal and Chemical Sciences JA - JMCS LA - en SN - AU - Alizadeh Otaghvar, Hamidreza AU - Amini, Farnaz AU - Pouya, Majid AU - Pakseresht, Saeid AU - Dahmardehei, Mostafa AU - Jafarian, Aliakbar AU - Milani Fard, Maryam AD - Associated Professor of Plastic Surgery, Truma and Injury Research Center, Iran University of Medical Sciences, Tehran, Iran AD - General Practitioner, Tonekabon Islamic Azad University of Medical Sciences, Tonekabon, Iran AD - Assistant Professor of Surgery Group of Tonekabon Islamic Azad University of Medical Sciences, Tonekabon, Iran AD - Associate Professor of Plastic Surgery Group of Iran University of Medical Sciences, Trauma Injury Research Center of Iran University of Medical Sciences, Tehran, Iran AD - Associate Professor of Anesthesiology, Iran University of Medical Sciences, Iran AD - Researcher at the Anesthesia and Pain & Molecular and Cell Biology Research center, Faculty of Medicine, Department of Anatomy, Iran University of Medical Sciences, Tehran, Iran Y1 - 2022 PY - 2022 VL - 5 IS - 4 SP - 449 EP - 456 KW - Mastopexy Scar KW - Butax KW - VANCOVVER Scale KW - Injected Groups DO - 10.26655/JMCHEMSCI.2022.4.1 N2 - Scar management is a critical challenging object in plastic surgery that influences life quality and can induce depression and functional disturbances. Hypertrophic scars and keloids after surgery, especially in cosmetic surgeries, can cause inappropriate appearance and excess costs to decrease the scar. Moreover, spiritual disturbance and psychological problems can occur, which lead to objections against physicians. Multi-disciplinary treatments like Butax injection have been suggested. This study is a case-control type. The cases are 20 patients attending Mehr Surgical Center and Rasoul-e- Akram hospital in Tehran diagnosis of hypertrophic scars or keloids after surgical mastopexy from February 2018 to February 2019. Four characteristics like width, height, color, and pliability were studied according to surgery scar. Also, the patient’s age, smoking, pleasure, and previous history of hypertrophic scars and keloids are Surveyed. In each of the patients, Butax is injected in right breast scar without any injection in the contralateral side as a control group and all patients studied for 18 months. At the end, data was analyzed with the SPSS 22 software. This study achieved meaningful differences between with and without Butax injected groups. According to Vancouver scale, the width, height, color, and pliability achieved higher scores meaningfully. In addition, the pleasure of patients in injected groups has achieved a higher score. There was a meaningful correlation between smoking and pleasure score in these patients, but we did not find a meaningful relationship with age. UR - https://www.jmchemsci.com/article_143142.html L1 - https://www.jmchemsci.com/article_143142_6b7343db0d50ead9a4a0eee44096e1b1.pdf ER -