ORIGINAL_ARTICLE
Factors Associated with Risk Perception towards Coronavirus 2019 (COVID-19) Among Students of Sirindhorn College of Public Health, Khon Kaen Province, Thailand
This cross-sectional study aimed to identify factors associated with risk perception towards COVID-19 among Sirindhorn college of public health Khon Kaen province students. Various health education and psychological models suggest that a primary driver of habits is risk perception. Protective habits are more likely to be adopted by people who experience greater risk, affecting the likelihood of infection. Two multistage random samplings made up a total of 360 participants. The data were collected via a structured questionnaire from April to May 2020. Frequency, percentage, mean, standard deviation, median, minimum, maximum, and multiple logistic regression models (with 95% CI) were computed to determine the possible associated factors to risk perception towards COVID-19. The finding revealed that more than half of the respondents were of good perception (74.44%; 95 % CI [69.61 to 78.87]), and most of the participants were female (88.33%), with an average age of 20.51 years old (S.D.=1.82). The factors associated with a good risk perception of COVID-19 including knowledge (AOR= 3.44, p-value = 0.023, 95% CI [1.15, 10.27]), and behaviour level of COVID-19 protection presented at a moderate and good level (AOR= 2.47, p-value = 0.045, 95% CI [1.13, 5.41] and AOR= 4.61, p-value = 0.001, 95% CI [2.04, 10.41], respectively). There should be the campaign for increasing the behaviour focus on the new normal behaviour. Moreover, the college should have a COVID-19 consult system to decrease the number of participants worried about COVID-19.
https://www.jmchemsci.com/article_129538_b181f4f650bd95f73fefa49eeee0e225.pdf
2021-05-01
215
224
10.26655/JMCHEMSCI.2021.3.1
risk perception
COVID-19
Questionnaire
logistic regression models
Kritkantorn
Suwannaphant
kritkantorn.suwannaphant@gmail.com
1
Sirindhorn College of Public Health, Khon Kaen province, Faculty of Public Health and Allied Health Sciences, Praboromarajchanok Institute, Thailand
AUTHOR
Pattamawadee
Duangkanya
shukribinbakar@gmail.com
2
Sirindhorn College of Public Health, Khon Kaen province, Faculty of Public Health and Allied Health Sciences, Praboromarajchanok Institute, Thailand
AUTHOR
Chanoknan
Saensunon
irinakrish2000@gmail.com
3
Sirindhorn College of Public Health, Khon Kaen province, Faculty of Public Health and Allied Health Sciences, Praboromarajchanok Institute, Thailand
AUTHOR
Sukanya
Kansin
fominadaniel@gmail.com
4
Ratchathani University Udonthani Campus, Thailand
LEAD_AUTHOR
Chinnawat
Phonsakkwa
parishani.amir@gmail.com
5
Sirindhorn College of Public Health, Khon Kaen province, Faculty of Public Health and Allied Health Sciences, Praboromarajchanok Institute, Thailand
AUTHOR
Panita
Wongsaming
vahid.nourani1975@gmail.com
6
Sirindhorn College of Public Health, Khon Kaen province, Faculty of Public Health and Allied Health Sciences, Praboromarajchanok Institute, Thailand
AUTHOR
Sirimin
Chuekuna
esfehani.mohamad3@gmail.com
7
Sirindhorn College of Public Health, Khon Kaen province, Faculty of Public Health and Allied Health Sciences, Praboromarajchanok Institute, Thailand
AUTHOR
Wichuta
Saengphet
mojakresearch3@gmail.com
8
Naku Health Promoting Hospital, Na Kae District, Nakhon Phanom Province, Thailand
AUTHOR
Noor Alis
Setiyadi
mh.mahmoodik@gmail.com
9
Public Health Department, Faculty of Health Science, Universitas Muhammadiyah Surakarta, Indonesia
AUTHOR
Mitoriana
Porusia
mitorianaporusia@gmail.com
10
Public Health Department, Faculty of Health Science, Universitas Muhammadiyah Surakarta, Indonesia
AUTHOR
[1]. Huang C., Wang Y., Li X., Ren L., Zhao J., Hu Y., Zhang L., Fan G., Xu J., Gu X., The lancet, 2020, 395:497 [Crossref], [Google scholar], [Publisher]
1
[2]. Lau H., Khosrawipour V., Kocbach P., Mikolajczyk A., Schubert J., Bania J., Khosrawipour T., J. Travel Med., 2020, 27:37 [Crossref], [Google scholar], [Publisher]
2
[3]. Lau H., Khosrawipour V., Kocbach P., Mikolajczyk A., Schubert J., Bania J., Khosrawipour T., Am. J. Respir. Crit. Care Med., 2020, 201:1372 [Crossref], [Google scholar], [Publisher]
3
[4]. Jernigan D.B., COVID C., Team R., Morb. Mortal. Wkly. Rep., 2020, 69:140 [Crossref], [Google scholar], [Publisher]
4
[5]. Mighani H., Hajiaghaei F., J. Med. Chem. Sci., 2021, 15:84 [Crossref], [Google scholar], [Publisher]
5
[6]. Wang S., Kang B., Ma J., Zeng X., Xiao M., Guo J., Cai M., Yang J., Li Y., Meng X., MedRxiv, 2020 [Crossref], [Google scholar], [Publisher]
6
[7]. Suntronwong N., Thongpan I., Chuchaona W., Budi Lestari F., Vichaiwattana P., Yorsaeng R., Pasittungkul S., Kitphati R., Vongpunsawad S., Poovorawan Y., Pathog. Glob. Health, 2020, 114:225 [Crossref], [Google scholar], [Publisher]
7
[8]. Pongpirul W.A., Mott J.A., Woodring J.V., Uyeki T.M., MacArthur J.R., Vachiraphan A., Suwanvattana P., Uttayamakul S., Chunsuttiwat S., Chotpitayasunondh T., Emerg. Infect. Dis., 2020, 26:1580 [Crossref], [Google scholar], [Publisher]
8
[9]. Di Gennaro F., Pizzol D., Marotta C., Antunes M., Racalbuto V., Veronese N., Smith L., Int. J. Environ. Res. Public. Health, 2020, 17:2690 [Crossref], [Google scholar], [Publisher]
9
[10]. Centers for Disease Control and Prevention, Guidance for cleaning and disinfecting public spaces, workplaces, businesses, schools, and homes. United States Environmental Protection Agency, 2020 [PDF], [Google scholar]
10
[11]. Hsieh F.Y., Bloch D.A., Larsen M.D., Stat. Med., 1998, 17:1623 [Crossref], [Google scholar], [Publisher]
11
[12]. Sangi S., Zargham Hajbi M., Ashayeri H., Aghaseofi A., J. Med. Chem. Sci., 2020, 3:345 [Crossref], [Google scholar], [Publisher]
12
[13]. Ding Y., Du X., Li Q., Zhang M., Zhang Q., Tan X., Liu Q., PloS One, 2020, 15:e0237626 [Crossref], [Google scholar], [Publisher]
13
[14]. Mya Kyaw S., Aye S.M., Hlaing Win A., Hlaing Su S., Thida A., Int. j. community med. public health, 2020, 7:1627 [Crossref], [Google scholar], [Publisher]
14
[15]. Afzal M.S., Khan A., Qureshi U.U.R., Saleem S., Saqib M.A.N., Shabbir R.M.K., Naveed M., Jabbar M., Zahoor S., Ahmed H., J. Community Health, 2020, 13:1 [Crossref], [Google scholar], [Publisher]
15
[16]. Khan M.U., Shah S., Ahmad A., Fatokun O., BMC Public Health, 2014, 14:1 [Crossref], [Google scholar], [Publisher]
16
[17]. Gautret P., Benkouiten S., Salaheddine I., Belhouchat K., Drali T., Parola P., Brouqui P., Eurosurveillance, 2013, 18:20604 [Crossref], [Google scholar], [Publisher]
17
[18]. Kim J.S., Choi J.S., J. Clin. Nurs., 2016, 25:2542 [Crossref], [Google scholar], [Publisher]
18
[19]. Wang Y., Wang Y., Chen Y., Qin Q., J. Med. Virol., 2020, 92:568 [Crossref], [Google scholar], [Publisher]
19
[20]. Liu Y., Gayle A.A., Wilder-Smith A., Rocklöv J., J. Travel Med., 2020, 27:27 [Crossref], [Google scholar], [Publisher]
20
[21]. Huynh T.D., medRxiv, 2020 [Crossref], [Google scholar], [Publisher]
21
[22]. Beaujean D.J.M.A., Bults M., van Steenbergen J.E., Voeten H.A.C.M., BMC Public Health, 2013, 13:1 [Crossref], [Google scholar], [Publisher]
22
[23]. Brewer N.T., Weinstein N.D., Cuite C.L., Herrington J.E., Ann. Behav. Med., 2004, 27:125 [Crossref], [Google scholar], [Publisher]
23
[24]. Ning L., Niu J., Bi X., Yang C., Liu Z., Wu Q., Ning N., Liang L., Liu A., Hao Y., BMC Public Health, 2020, 20:1 [Crossref], [Google scholar], [Publisher]
24
[25]. Witte K., Berkowitz J.M., Cameron K.A., McKeon J.K., Health Educ. Behav., 1998, 25:571 [Crossref], [Google scholar], [Publisher]
25
ORIGINAL_ARTICLE
A Review on Applications of Carbon Nanotubes (CNTs) in Solar Cells
The world is looking for clean, renewable and cheap energy. For a long time, researchers have been trying to find materials to achieve this goal. The discovery of carbon nanotubes (CNTs) has opened new horizons in the field of their uses in the field of solar energy. The chemistry of carbon nanotubes involves chemical reactions that are used to change the properties of carbon nanotubes (CNTs). To attain desired properties that can be used in a wide range of applications, CNTs can be functionalized. Covalent and non-covalent modifications are the two primary types of CNT functionalization. This review focuses on how to use the synthesized CNTs by flame fragments deposition (FFD) technique, which is an easy and cheap method in which CNTs can be prepared at lower temperatures compared with other traditional techniques, in preparing CNTs composites in solar cell components to improve charge conduction, electrode flexibility and acting as active light absorbing materials.
https://www.jmchemsci.com/article_129913_cde2b3baf71d00a82cd2689ebf3694cf.pdf
2021-05-01
225
229
10.26655/JMCHEMSCI.2021.3.2
CNT
Solar cell, pharmaceutical applications, chemical reactions
Samaa Saadi
Mahmood
irinakrish2000@gmail.com
1
Department of Chemistry, College of Science, University of Babylon Hilla, Iraq
AUTHOR
Abbas J.
Atiya
shukribinbakar@gmail.com
2
Department of Chemistry, College of Science, University of Babylon Hilla, Iraq
AUTHOR
Firas H.
Abdulrazzak
parishani.amir@gmail.com
3
Chemistry Department, College of Education for Pure Sciences, Diyala University, Iraq
AUTHOR
Ayad F.
Alkaim
vahid.nourani1975@gmail.com
4
College of Science for Woman, University of Babylon, Iraq
LEAD_AUTHOR
Falah H.
Hussein
fominadaniel@gmail.com
5
College of Pharmacy, University of Babylon, Hilla, Iraq
AUTHOR
[1]. Taniguchi N., Proceeding ICPE, 1974 [Google scholar], [Publisher]
1
[2]. Masciangioli T., Zhang W.-X., Environ. Sci. Technol. 2003, 37, 5:102A [Crossref], [Google scholar], [Publisher]
2
[3]. Fidelis G.K., Louis H., Tizhe T.F., Onoshe S., J. Med. Chem. Sci., 2019, 2:59 [Crossref], [Google scholar], [Publisher]
3
[4]. Fazal-ur-Rehman M., Qayyum I., J. Med. Chem. Sci., 2020, 3:399 [Crossref], [Google scholar], [Publisher]
4
[5]. Iijima S., nature, 1991, 354:56 [Crossref], [Google scholar], [Publisher]
5
[6]. Borm P.J., Robbins D., Haubold S., Kuhlbusch T., Fissan H., Donaldson K., Schins R., Stone V., Kreyling W., Lademann J., Part. Fibre Toxicol., 2006, 3:1 [Crossref], [Google scholar], [Publisher] [7]. Ahmadpour A., Shahsavand A., Shahverdi M.R., in Proc. 4th Bienn. Conf. Environ. Spec. Assoc. Tehran, 2003 [Crossref], [Google scholar], [Publisher]
6
[8]. Zhu G., Huang Z., Xu Z., Yan L.-T., Acc. Chem. Res., 2018, 51:900 [Crossref], [Google scholar], [Publisher]
7
[9]. Yao K., Zhong H., Liu Z., Xiong M., Leng S., Zhang J., Xu Y., Wang W., Zhou L., Huang H., ACS Nano, 2019, 13:5397 [Crossref], [Google scholar], [Publisher]
8
[10]. Jauffred L., Samadi A., Klingberg H., Bendix P.M., Oddershede L.B., Chem. Rev., 2019, 119:8087 [Crossref], [Google scholar], [Publisher]
9
[11]. Ha M., Kim J.-H., You M., Li Q., Fan C., Nam J.-M., Chem. Rev., 2019, 119:12208 [Crossref], [Google scholar], [Publisher]
10
[12]. Kim H., Abdala A.A., Macosko C.W., Macromolecules, 2010, 43:6515 [Crossref], [Google scholar], [Publisher]
11
[13]. Huang X., Jiang P., Tanaka T., IEEE Electr. Insul. Mag., 2011, 27:8 [Crossref], [Google scholar], [Publisher]
12
[14]. Kojima Y., Usuki A., Kawasumi M., Okada A., Fukushima Y., Kurauchi T., Kamigaito O., J. Mater. Res., 1993, 8:1185 [Crossref], [Google scholar], [Publisher]
13
[15]. Levchenko V., Mamunya Y., Boiteux G., Lebovka M., Alcouffe P., Seytre G., Lebedev E., Eur. Polym. J., 2011, 47:1351 [Crossref], [Google scholar], [Publisher]
14
[16]. Kojima Y., Usuki A., Kawasumi M., Okada A., Kurauchi T., Kamigaito O., J. Polym. Sci. Part Polym. Chem., 1993, 31:983 [Crossref], [Google scholar], [Publisher]
15
[17]. Helland A., Wick P., Koehler A., Schmid K., Som C., Environ. Health Perspect., 2007, 115:1125 [Crossref], [Google scholar], [Publisher]
16
[18]. Kroto H.W., Heath J.R., O’Brien S.C., Curl R.F., Smalley R.E., nature, 1985, 318:162 [Crossref], [Google scholar], [Publisher]
17
[19]. Takakura A., Beppu K., Nishihara T., Fukui A., Kozeki T., Namazu T., Miyauchi Y., Itami K., Nat. Commun., 2019, 10:1 [Crossref], [Google scholar], [Publisher]
18
[20]. Rao R., Pint C.L., Islam A.E., Weatherup R.S., Hofmann S., Meshot E.R., Wu F., Zhou C., Dee N., Amama P.B., ACS Nano, 2018, 12:11756 [Crossref], [Google scholar], [Publisher]
19
[21]. Mohanta D., Patnaik S., Sood S., Das N., J. Pharm. Anal., 2019, 9:293 [Crossref], [Google scholar], [Publisher]
20
[22]. Kinloch I.A., Suhr J., Lou J., Young R.J., Ajayan P.M., Science, 2018, 362:547 [Crossref], [Google scholar], [Publisher]
21
[23]. He X., Htoon H., Doorn S.K., Pernice W.H.P., Pyatkov F., Krupke R., Jeantet A., Chassagneux Y., Voisin C., Nat. Mater., 2018, 17:663 [Crossref], [Google scholar], [Publisher]
22
[24]. Kamble R.D., Gaikwad M.V., Tapare M.R., Hese S.V., Kadam S.N., Ambhore A.N., Dawane B.S., J. Appl. Organomet. Chem., 2021, 1:22 [Crossref], [Google scholar], [Publisher]
23
[25]. Iijima S., Ichihashi T., nature, 1993, 363:603 [Crossref], [Google scholar], [Publisher]
24
[26]. Cherukuri P., Bachilo S.M., Litovsky S.H., Weisman R.B., J. Am. Chem. Soc., 2004, 126:15638 [Crossref], [Google scholar], [Publisher]
25
[27]. Eatemadi A., Daraee H., Karimkhanloo H., Kouhi M., Zarghami N., Akbarzadeh A., Abasi M., Hanifehpour Y., Joo S.W., Nanoscale Res. Lett., 2014, 9:1 [Crossref], [Google scholar], [Publisher]
26
[28]. Hirlekar R., Yamagar M., Garse H., Vij M., Kadam V., Asian J. Pharm. Clin. Res., 2009, 2:17 [Crossref], [Google scholar], [Publisher]
27
[29]. Hammadi A.H., Abdulrazzak F.H., Atiyah A.J., Hussein F.H., Org. Med. Chem. IJ, 2017, 29:2804 [Crossref], [Google scholar], [Publisher]
28
[30]. Hammadi A.H., Jasim A.M., Abdulrazzak F.H., Al-Sammarraie A., Cherifi Y., Boukherroub R., Hussein F.H., Materials, 2020, 13:2342 [Crossref], [Google scholar], [Publisher]
29
[31]. Baughman R.H., Zakhidov A.A., De Heer W.A., science, 2002, 297:787 [Crossref], [Google scholar], [Publisher]
30
[32]. Shinde A., Adole V.A.,J. Appl. Organomet. Chem., 2021, 1:48 [Crossref], [Google scholar], [Publisher]
31
[33]. Wohlgemuth J.H., Narayanan S., in Conf. Rec. Twenty-Second IEEE Photovolt. Spec. Conf.-1991, IEEE, 1991:273 [Crossref], [Google scholar], [Publisher]
32
[34]. Kim B.-J., Han S.-H., Park J.-S., Surf. Coat. Technol., 2015, 271:22 [Crossref], [Google scholar], [Publisher]
33
[35]. Abd Alrazzak N., Aowda S.A., Atiyah A.J., Orient. J. Chem., 2017, 33:2476 [PDF], [Google scholar], [Publisher]
34
[36]. Chen J.Z., Yan Y.C., Lin K.J., J. Chin. Chem. Soc., 2010, 57:1180 [Crossref], [Google scholar], [Publisher]
35
[37]. Huang H., Kajiura H., Tsutsui S., Murakami Y., Ata M., J. Phys. Chem. B, 2003, 107:8794 [Crossref], [Google scholar], [Publisher]
36
[38]. Baxter J.B., Aydil E.S., Appl. Phys. Lett., 2005, 86:053114 [Crossref], [Google scholar], [Publisher]
37
[39]. Jayawardena K.I., Rozanski L.J., Mills C.A., Beliatis M.J., Nismy N.A., Silva S.R.P., Nanoscale, 2013, 5:8411 [Crossref], [Google scholar], [Publisher]
38
[40]. Hara K., Kurashige M., Dan-oh Y., Kasada C., Shinpo A., Suga S., Sayama K., Arakawa H., New J. Chem., 2003, 27:783 [Crossref], [Google scholar], [Publisher]
39
[41]. Widodo S., Wiranto G., Hidayat M.N., Energy Procedia, 2015, 68:37 [Crossref], [Google scholar], [Publisher]
40
[42]. Lenzmann F.O., Kroon J.M., Adv. Optoelectron., 2007, 2007 [Crossref], [Google scholar], [Publisher]
41
[43]. Chen L., Tan W., Zhang J., Zhou X., Zhang X., Lin Y., Electrochimica Acta, 2010, 55:3721 [Crossref], [Google scholar], [Publisher]
42
[44]. Ma J., Zhou L., Li C., Yang J., Meng T., Zhou H., Yang M., Yu F., Chen J., J. Power Sources, 2014, 247:999 [Crossref], [Google scholar], [Publisher]
43
[45]. Kim H., Choi H., Hwang S., Kim Y., Jeon M., Nanoscale Res. Lett., 2012, 7:1 [Crossref], [Google scholar], [Publisher]
44
ORIGINAL_ARTICLE
Relationship of Immune Indicators and Structural and Functional Properties of Erythrocytes in Chronic Endometritis
This study dealt with women of childbearing age with infertility against the background of the chronic inflammatory process in the stage of incomplete clinical remission, pronounced changes from pro, anti-inflammatory, regulatory cytokines, components and inhibitors of the complement system. Changes in the architectonics of proteins lead to serious functional disorders properties of peripheral blood erythrocytes in chronic kidney disease even in remission. The composition of blood plasma changes significantly during pathology, which in turn has a significant effect on cell morphology, lipid-protein interactions and the latter-related activity of its enzyme systems. There is a "tension" of the immune and metabolic statuses, which can serve to assess the severity of the disease, its prognosis, treatment effectiveness and preventive measures. "Women with infertility in chronic endometritis and infertility in kidney disease with infertility" was published by the European Society for Human Reproduction and Developmental Disorder (ESDD) in May 2013. The study found that despite the absence of clinical manifestations of inflammation, there was a destructive immune-inflammatory process that requires mandatory correction.
https://www.jmchemsci.com/article_129980_016befcd3fe6003c75584c5854ab161d.pdf
2021-05-01
230
237
10.26655/JMCHEMSCI.2021.3.3
chronic endometritis
demographic situation
fertilization
Reproductive Health
Olga A.
Sunyaikina
irinakrish2000@gmail.com
1
Biological chemistry department, FGBEE HE «Kursk State Medical University» (KSMU) 305040, Russian Federation, Kursk city, K. Marx Street 3
LEAD_AUTHOR
Aleksey A.
Konoplya
shukribinbakar@gmail.com
2
Biological chemistry department, FGBEE HE «Kursk State Medical University» (KSMU) 305040, Russian Federation, Kursk city, K. Marx Street 3
AUTHOR
Irina I.
Kolomoets
vahid.nourani1975@gmail.com
3
Biological chemistry department, FGBEE HE «Kursk State Medical University» (KSMU) 305040, Russian Federation, Kursk city, K. Marx Street 3
AUTHOR
Vera A.
Ragulina
fominadaniel@gmail.com
4
Biological chemistry department, FGBEE HE «Kursk State Medical University» (KSMU) 305040, Russian Federation, Kursk city, K. Marx Street 3
AUTHOR
Tatiana M.
Grigorieva
anarbekovadzhumabaevna@gmail.com
5
Biological chemistry department, FGBEE HE «Kursk State Medical University» (KSMU) 305040, Russian Federation, Kursk city, K. Marx Street 3
AUTHOR
[1]. Balykina Y.E., Kolpak E.P., Kotina E.D., Middle East J. Sci. Res., 2014, 19:429 [Crossref], [Google scholar], [Publisher]
1
[2]. Thong E.P., Codner E., Laven J.S., Teede H., Lancet Diabetes Endocrinol., 2020, 8:134 [Crossref], [Google scholar], [Publisher]
2
[3]. Pandey A.K., Gupta A., Tiwari M., Prasad S., Pandey A.N., Yadav P.K., Sharma A., Sahu K., Asrafuzzaman S., Vengayil D.T., Biomed. Pharmacother., 2018, 103:46 [Crossref], [Google scholar], [Publisher]
3
[4]. Odo A.N., Samuel E.S., Nwagu E.N., Nnamani P.O., Atama C.S., BMC Health Serv. Res., 2018, 18:1 [Crossref], [Google scholar], [Publisher]
4
[5]. Mena G.P., Mielke G.I., Brown W.J., Hum. Reprod. Update, 2019, 25:542 [Crossref], [Google scholar], [Publisher]
5
[6]. Ljungman L., Ahlgren J., Petersson L.-M., Flynn K.E., Weinfurt K., Gorman J.R., Wettergren L., Lampic C., Psychooncology., 2018, 27:2770 [Crossref], [Google scholar], [Publisher]
6
[7]. Damra J.K., Abujilban S., J. Interpers. Violence, 2018, 36:NP3044 [Crossref], [Google scholar], [Publisher]
7
[8]. Latha N.L., Gyananath G., Kasa A., Zubaidha P.K., J. Med. Chem. Sci., 2019, 2:46 [Crossref], [Google scholar], [Publisher]
8
[9]. Ataei Moghadam S., Rostami Charati F., Akbari R., Gholamalipour Alamdari E., Behmanesh B., J. Med. Chem. Sci., 2020, 3:245 [Crossref], [Google scholar], [Publisher]
9
[10]. Adole V.A., J. Appl. Organomet. Chem., 2021, 1:29 [Crossref], [Google scholar], [Publisher]
10
[11]. Song D., Feng X., Zhang Q., Xia E., Xiao Y., Xie W., Li T.C., Reprod. Biomed. Online, 2018, 36:78 [Crossref], [Google scholar], [Publisher]
11
[12]. Liu Y., Chen X., Huang J., Wang C.-C., Yu M.-Y., Laird S., Li T.-C., Fertil. Steril., 2018, 109:832 [Crossref], [Google scholar], [Publisher]
12
[13]. Kupina A.D., Petrov Y.A., Indo Am. J. Pharm. Sci., 2019, 6:15210 [Crossref], [Google scholar], [Publisher]
13
[14]. Kimura F., Takebayashi A., Ishida M., Nakamura A., Kitazawa J., Morimune A., Hirata K., Takahashi A., Tsuji S., Takashima A., J. Obstet. Gynaecol. Res., 2019, 45:951 [Crossref], [Google scholar], [Publisher]
14
[15]. Cicinelli E., Matteo M., Trojano G., Mitola P.C., Tinelli R., Vitagliano A., Crupano F.M., Lepera A., Miragliotta G., Resta L., Am. J. Reprod. Immunol., 2018, 79:e12782 [Crossref], [Google scholar], [Publisher]
15
[16]. Măluţan A.M., Drugan T., Ciortea R., Mocan-Hognogi R.F., Bucuri C., Rada M.P., Mihu D., J. Res. Med. Sci. Off. J. Isfahan Univ. Med. Sci., 2015, 20:668 [Crossref], [Google scholar], [Publisher]
16
[17]. Thézénas M.-L., De Leo B., Laux-Biehlmann A., Bafligil C., Elger B., Tapmeier T., Morten K., Rahmioglu N., Dakin S.G., Charles P., Sci. Rep., 2020, 10:1 [Crossref], [Google scholar], [Publisher]
17
[18]. Erten O.U., Ensari T.A., Dilbaz B., Cakiroglu H., Altinbas S.K., Caydere M., Goktolga U., Taiwan. J. Obstet. Gynecol., 2016, 55:251 [Crossref], [Google scholar], [Publisher]
18
[19]. Valle R.F., Int. J. Gynecol. Obstet., 2002, 78:107 [Crossref], [Google scholar], [Publisher]
19
[20]. Yeniçerioglu Y., Üzelce Ö., Akar H., Kolatan E., Yilmaz O., Yenisey Ç., Sarioglu S., Meteoglu I., Ren. Fail., 2010, 32:1095 [Crossref], [Google scholar], [Publisher]
20
[21]. Biradar S.B., Narte D.V., Kale R.P., Momin K.I., Sudewad M.S., Tayade K.C., Palke D.G., J. Appl. Organomet. Chem., 2021, 1:41 [Crossref], [Google scholar], [Publisher]
21
[22]. Bae S.C., Jung W.J., Lee E.J., Yu R., Sung M.K., J. Am. Coll. Nutr., 2009, 28:56 [Crossref], [Google scholar], [Publisher]
22
[23]. Madazli R., Benian A., Gümüştaş K., Uzun H., Ocak V., Aksu F., Eur. J. Obstet. Gynecol. Reprod. Biol., 1999, 85:205 [Crossref], [Google scholar], [Publisher]
23
[24]. Amirkhizi F., Siassi F., Minaie S., Djalali M., Rahimi A., Chamari M., Arya Atheroscler., 2010, 2:189 [PDF], [Google scholar], [Publisher]
24
[25]. Cicinelli E., Trojano G., Mastromauro M., Vimercati A., Marinaccio M., Mitola P.C., Resta L., de Ziegler D., Fertil. Steril., 2017, 108:289 [Crossref], [Google scholar], [Publisher]
25
ORIGINAL_ARTICLE
Improving Knowledge of Diabetes Mellitus Patients Using Booklet
This research aimed to determine the increase in knowledge of Diabetes Mellitus patients through a booklet. This quantitative study followed a quasi-experimental design with two groups of pretest-posttest, at Kartasura Sukoharjo community health centre in April 2019. We used the purposive sampling technique with 40 samples divided into 20 samples in the experimental group and 20 samples in the control group. The patients aged 50-65 years, registered at the Chronic Disease Management Program (prolanis) Kartasura Community Health Centre, without comorbidities participated in the study. We used a questionnaire containing 20 questions that was modified by researchers. Its validity was 0.443, and its reliability was 0.945. Wilcoxon test was used to analyse the data. The results showed that the pre-test results of the experimental group showed a mean of 9.35, post-test of 12.95, and a P-value of 0.001. The pre-test results of the control group showed a mean of 11.00, post-test of 10.90, and P value of 0.414. There was also an in-depth study of the material by dividing it into small groups and giving booklets so that respondents could remember and do it at home. As for chronic disease patients, the more often they socialize, the less burden they feel.
https://www.jmchemsci.com/article_129982_d0559e010edc99b1d476b096457074ba.pdf
2021-05-01
238
245
10.26655/JMCHEMSCI.2021.3.4
Diabetes Mellitus
quasi-experimental
purposive sampling technique
chronic disease management
Wachidah
Yuniartika
wachidah.yuniartika@gmail.com
1
Community and gerontology Nursing Department, School of Nursing, Faculty of Health Science Universitas Muhammadiyah Surakarta, Indonesia
LEAD_AUTHOR
Dwitiya Ary
Nur Hidayati
vahid.nourani1975@gmail.com
2
Community and gerontology Nursing Department, School of Nursing, Faculty of Health Science Universitas Muhammadiyah Surakarta, Indonesia
AUTHOR
[1]. Bull F.C., Al-Ansari S.S., Biddle S., Borodulin K., Buman M.P., Cardon G., Chaput J.P., Chastin S., Chou R., Dempsey P.C., Br. J. Sports Med., 2020, 54:1451 [Crossref], [Google scholar], [Publisher]
1
[2]. Sohrabi C., Alsafi Z., O'Neill N., Khan M., Kerwan A., Al-Jabir A., Iosifidis C., Agha R.,Int. J. Surg., 2019, 76:71 [Crossref], [Google scholar], [Publisher]
2
[3]. Andriyaningtiyas Y., Tamtomo D.G., Murti B., J. Health Promot. Behav., 2020, 5:59 [PDF], [Google scholar], [Publisher]
3
[4]. Mihardja L., Soetrisno U., Soegondo S., J. Diabetes Investig., 2014, 5:507 [PDF], [Google scholar], [Publisher]
4
[5]. Alimohammadi M., Sharifi-Daramadi P., Noohi S., J. Med. Chem. Sci., 2020, 3:286 [Crossref], [Google scholar], [Publisher]
5
[6]. Dogo D.W., Louis H., I Iliya N., U Ozioma A., T Aderemi A., Stware B., J. Med. Chem. Sci., 2019, 2:162 [Crossref], [Google scholar], [Publisher]
6
[7]. Anggraini D., Herdiman H., Triatmaka J.C., in Int. Conf. Heath Care Manag. 2018, 2018, 1 [Google scholar]
7
[8]. Hartayu T.S., Mi M.I., Suryawati S., BMC Res. Notes, 2012, 5:1 [Crossref], [Google scholar], [Publisher]
8
[9]. Murtaqib M., Rondhianto R., Rizqiyyah N.A., J. Nurs. Care, 2020, 2:1 [Crossref], [Google scholar], [Publisher]
9
[10]. Tjahjono H.A., Int. J. Pediatr. Endocrinol., 2013, 2013:1 [Crossref], [Google scholar], [Publisher]
10
[11]. Sieck J.O., Textbook of Internal Medicine. King Faisal Specialist Hospital & Research Centre, 1994 [Crossref], [Google scholar], [Publisher]
11
[12]. Sulistiowati E., Sihombing M., 4th Int. Symp. Health Res. ISHR 2019, Atlantis Press, 2020:74 [Crossref], [Google scholar], [Publisher]
12
[13]. Nusrianto R., Ayundini G., Kristanti M., Astrella C., Amalina N., Riyadina W., Tahapary D.L., Soewondo P., Diabetes Res. Clin. Pract., 2019, 155:107798 [Crossref], [Google scholar], [Publisher]
13
[14]. Nurharianti P.R., Kodim N., Indian J. Public Health Res. Dev., 2019, 10:1911 [Crossref], [Google scholar], [Publisher]
14
[15]. Kosupa D.Z., Utama F., in 2nd Sriwij. Int. Conf. Public Health SICPH 2019, Atlantis Press, 2020:228 [Crossref], [Google scholar], [Publisher]
15
[16]. Bener A., Zirie M., Janahi I.M., Al-Hamaq A.O., Musallam M., Wareham N.J., Diabetes Res. Clin. Pract., 2009, 84:99 [Crossref], [Google scholar], [Publisher]
16
[17]. Rubinelli S., Diviani N., Patient Educ. Couns., 2020, 103:2395 [Crossref], [Google scholar], [Publisher]
17
[18]. Aponte J., Jackson T.D., Wyka K., Ikechi C., Diab. Vasc. Dis. Res., 2017, 14:316 [Crossref], [Google scholar], [Publisher]
18
[19]. Zhang Y., Chu L., Int. J. Endocrinol., 2018, 2018 [Crossref], [Google scholar], [Publisher]
19
[20]. Moreno E.G., Mateo-Abad M., de Retana García L.O., Vrotsou K., del Campo Pena E., Perez Á.S., Carazo C.M., Ortiz J.C.A., Portu M.Á.R., Elorriaga K.P., Prim. Care Diabetes, 2019, 13:122 [Crossref], [Google scholar], [Publisher]
20
[21]. Pratiwi I.N., Hidayati L., Nursalim M., Oncol. Nurs. Forum., 2016, 43:342 [Crossref], [Google scholar], [Publisher]
21
[22]. Baharuddin B., Nasrullah N., Muhasidah M., Angriani S., Health Notions, 2018, 2:927 [PDF], [Google scholar], [Publisher]
22
[23]. Contreras F., Sanchez M., Martinez M.S., Castillo M.C., Mindiola A., Bermudez V., Velasco M., Med Clin Rev, 2017, 3:7 [Crossref], [Google scholar], [Publisher]
23
[24]. Alanazi F.K., Alotaibi J.S., Paliadelis P., Alqarawi N., Alsharari A., Albagawi B., Saudi Med. J., 2018, 39:981 [Crossref], [Google scholar], [Publisher]
24
[25]. Zhao X., Yu X., Zhang X., J. Diabetes Res., 2019, 2019 [Crossref], [Google scholar], [Publisher]
25
[26]. Yuniartika W., Dwidiyanti M., Mu’in M., Int. J. Res. Med. Sci., 2016, 4:3348 [Crossref], [Google scholar], [Publisher]
26
[27]. Chen S., Qian D., Burström K., Burström B., Patient Educ. Couns., 2020, 103:1767 [Crossref], [Google scholar], [Publisher]
27
[28]. Wichit N., Mnatzaganian G., Courtney M., Schulz P., Johnson M., Diabetes Res. Clin. Pract., 2017, 123:37 [Crossref], [Google scholar], [Publisher]
28
[29]. Salinero-Fort M.A., Carrillo-de Santa Pau E., Arrieta-Blanco F.J., Abanades-Herranz J.C., Martín-Madrazo C., Rodés-Soldevila B., de Burgos-Lunar C., BMC Public Health, 2011, 11:1 [Crossref], [Google scholar], [Publisher]
29
ORIGINAL_ARTICLE
The Effect of Perceived Value, Perceived Service Quality on Community Service Satisfaction: A Case of Bendan Hospital Patient in Pekalongan City
This research aimed to show how a company can improve its service quality of hospital community’s satisfaction through Perceived value and Perceived service quality through brand Trust which is appropriate with Law Number 25 of 2009 concerning with Public Service and Government Regulation Number 96 of 2012 concerning with the Implementation of Law Number 25 of 2009 concerning with Public Service. The data were collected by distributing questionnaires to respondents through google form. The population of this research included the health care service of Bendan Hospital in Pekalongan City in the second semester in 2020 with unknown number and the number of samples were 154 people, which was based on random sampling. PLS version 3 was used to test the hypothesis. The research result of perceived value and perceived service quality affected the hospital community’s satisfaction through the variable of brand trust mediation.
https://www.jmchemsci.com/article_130381_a32b67060735afaa847dfa1d85b58f14.pdf
1999-11-30
246
257
10.26655/JMCHEMSCI.2021.3.5
Brand Trust
Community service’ s satisfaction
perceived value
Perceived service quality
Hospital
.
Harsoyo
harsoyofisip17@gmail.com
1
Faculty of Social and Political Sciences, University of 17 August 1945 Semarang, Indonesia
LEAD_AUTHOR
Honorata Ratnawati Dwi
Putranti
ratna.permai@gmail.com
2
Faculty of Economics and Business, University of 17 August 1945 Semarang, Indonesia
AUTHOR
[1]. Herdyastuti D., Rahayu S., Germas A., J. Manaj. Admin. Rumah Sakit Indonesia., 2020, 4:134 [Google scholar], [Publisher]
1
[2]. Pareraway, D.C., Pharmacon, 2016 5:273 [Crossref], [Google scholar], [Publisher]
2
[3]. Donahue K. E., Ashkin E., Pathman D.E., BMC Fam. Pract., 2005, 6:1 [Crossref], [Google scholar], [Publisher]
3
[4]. Yoo D.K., Park J.A. Int. j qual. reliab. manage., 2007, 24:908 [Crossref], [Google scholar], [Publisher]
4
[5]. Zulfikar R., Mayvita P.A., j. ilm. bid. akunt. manaj., 2018, 15:1 [Crossref], [Google scholar], [Publisher]
5
[6]. Tanisah T., Maftukhah I., J. Dinamika Manaj., 2015, 6:55 [PDF], [Google scholar], [Publisher]
6
[7]. Chen J. J., Delongchamp R.R., Tsai C.A., Hsueh H.M., Sistare F., Thompson K.L., Desai V.G., Fuscoe J.C., Bioinformatics, 2004, 20:1436 [Crossref], [Google scholar], [Publisher]
7
[8]. Behnam M., Sato M., Baker B.J., Delshab V., Winand M., J. Sport Manag., 2020, 34:591 [Crossref], [Google scholar], [Publisher]
8
[9]. Kwon H.H., Trail G., James J.D J. Sport Manag., 2007, 21:540 [Crossref], [Google scholar], [Publisher]
9
[10]. Roig J.C.F., Garcia J.S., Tena M.A.M., Monzonis J.L., Int. J. Bank Mark., 2006, 24:266 [Crossref], [Google scholar], [Publisher]
10
[11]. Yang Z., Peterson R.T., Psychol. Mark. 2004, 21:799 [Crossref], [Google scholar], [Publisher]
11
[12]. Gumussoy C.A., Koseoglu, B., J. Econ. Bus. Manag., 2016, 4:9 [Crossref], [Google scholar], [Publisher]
12
[13]. Rivaldi M. P., Syahril E., Matto R. F., UMI Med.l J., 2019, 4:15 [Crossref], [Google scholar], [Publisher]
13
[14]. Gounaris S., Dimitriadis S., Stathakopoulos V., J. Serv. Mark., 2010, 24:142 [Crossref], [Google scholar], [Publisher]
14
[15]. Putro S., J. Strateg. Mark., 2014, 2:1 [PDF], [Google scholar], [Publisher]
15
[16]. Putra T.W., Keni K., J. Muara Ilmu Ekon. Bis., 2020, 4:184 [Crossref], [Google scholar], [Publisher]
16
[17]. Brakus J. J., Schmitt B. H., Zarantonello L., J. Mark., 2009, 73:52 [Crossref], [Google scholar], [Publisher]
17
[18]. Sánchez-Fernández R., Iniesta-Bonillo M. Á. J. Retail. Consum. Serv., 2009, 16:425 [Crossref], [Google scholar], [Publisher]
18
[19]. Vigripat T., Chan P., International DSI / Asia and Pacific DSI, 2007, 1 [PDF], [Google scholar]
19
[20]. Ramadhan S., Sunarto D.M., Prasetyo Z.K., Int. J. Adv. Sci. Technol., 2020, 29:5102 [PDF], [Google scholar], [Publisher]
20
[21]. Wihardjo R.S.D., Nurani Y., Ramadhan S., Nasaruddin, Int. J. Adv. Sci. Technol., 2019, 29:699 [PDF], [Publisher]
21
ORIGINAL_ARTICLE
The Effect of Family Psychoeducation Therapy on Stress of Families with Intellectual Disability Children at Special School
This study aims to determine the effect of family psychoeducation on parent stress caring for intellectual disability children. The study used a quasi-experimental pre-post-test design with a control group. The sample included 60 mothers with mentally retarded children, who were selected using purposive sampling technique to participate in nursing intervention and family psychoeducation therapy, with 30 mothers in the control group, and 30 in the intervention group. The criteria of sampling included parents or primary family caregivers who care for intellectual disability children and schools in SLB-C Depok city, take direct care and live in one house with children with intellectual disability, and read and write and communicate well. The questionnaire consisted of respondent demographic data and the family stress scale (Z=0.715 on the stress scale). To analyse the data, t-test dependent tests were use because all data were normally distributed. The results showed that nursing intervention and family psychoeducation therapy can reduce parents' stress level in caring for intellectual disability children (p-value < 0.005). The combination of nursing intervention and FPE had a great impact on mother capability to face their stress.
https://www.jmchemsci.com/article_130414_0ff41977a0fe9578178faebffe52785f.pdf
2021-05-01
258
266
10.26655/JMCHEMSCI.2021.3.6
family psychoeducation
intellectual disability
quasi-experimental
Demographic Data
nursing intervention
Nurlaila
Fitriani
fitriani.nurlaila@yahoo.com
1
Faculty of Health Sciences, Universitas Muhammadiyah Surakarta (UMS), Surakarta 57162, Indonesia
LEAD_AUTHOR
Achir Yani
S. Hamid
shukribinbakar@gmail.com
2
Mental Health Department, Faculty of Nursing, Universitas Indonesia, Depok, West Java 16424, Indonesia
AUTHOR
Herni
Susanti
parishani.amir@gmail.com
3
Mental Health Department, Faculty of Nursing, Universitas Indonesia, Depok, West Java 16424, Indonesia
AUTHOR
[1]. Alimohammadi M., Sharifi-Daramadi P., Noohi S., J. Med. Chem. Sci., 2020, 3:286 [Crossref], [Google scholar], [Publisher]
1
[2]. Keyghobadi S., Asadzadeh H., Darvizeh Z., J. Med. Chem. Sci., 2020, 3:373 [Crossref], [Google scholar], [Publisher]
2
[3]. Tassé M.J., Luckasson R., Schalock R.L., Intellect. Dev. Disabil., 2016, 54:381 [Crossref], [Google scholar], [Publisher]
3
[4]. Hargono A., Megatsari H., Artanti K.D., Nindya T.S., Wulandari R.D., J. Public Health Res., 2020, 9: 1809 [Crossref], [Google scholar], [Publisher]
4
[5]. Nugraha B., Setyono G.R., Defi I.R., Gutenbrunner C., J. Rehabil. Med., 2018, 50:377 [Crossref], [Google scholar], [Publisher]
5
[6]. Masulani-Mwale C., Kauye F., Gladstone M., and Mathanga, D., BMC Psychiatry., 2018, 18:146 [Crossref], [Google scholar], [Publisher]
6
[7]. Endriyani S., Yunike Y., Int. J. Public Health Sci., 2017, 6:331 [Crossref], [Google scholar], [Publisher]
7
[8]. Powell R.M., Parish S.L., Akobirshoev I., J. Appl. Res. Intellect. Disabil., 2017, 30:456 [Crossref], [Google scholar], [Publisher]
8
[9]. Gerstein E.D., Crnic K.A., Blacher J., Baker B.L., J. Intellect. Disabil Res., 2009, 53:981 [Crossref], [Google scholar], [Publisher]
9
[10]. Peer J.W., Hillman S.B., J. Intellect. Disabil., 2012, 16:45 [Crossref], [Google scholar], [Publisher]
10
[11]. Lazarus R.S., Fifty Years Res. Theory RS Lazarus. An Analysis of Historical and Perennial Issues, Psychology Press. 1993 [Google scholar], [Publisher]
11
[12]. Rodas N.V., Zeedyk S.M., Baker B.L., J. Intellect. Disabil. Res., 2016, 60:1200 [Crossref], [Google scholar], [Publisher]
12
[13]. Wiliyanarti P.F., Muhith A., NurseLine J., 2019, 4:54 [Crossref], [Google scholar], [Publisher]
13
[14]. Rekawati E., Hamid A.Y.S., Sahar J., Widyatuti W., Sari N.L.P.D.Y., J. Penelit. Kesehat. SUARA FORIKESJournal Health Res. Forikes Voice, 2019, 10:173 [PDF], [Google scholar], [Publisher]
14
[15]. Friedman M.M., Bowden V.R., Jones E.G., Family nursing: Research, theory, & practice (pp. 463–510). Upper Saddle River, NJ: Prentice Hall, 2002 [Google scholar], [Publisher]
15
[16]. Manor-Binyamini I., J. Autism Dev. Disord., 2011, 41:610 [Crossref], [Google scholar], [Publisher]
16
[17]. Uslu R., Erden G., Kapci E.G., Psychol. Rep., 2006, 98:291 [Crossref], [Google scholar], [Publisher]
17
[18]. Ferrin M., Perez-Ayala V., El-Abd S., Lax-Pericall T., Jacobs B., Bilbow A., Taylor E., J. Atten. Disord., 2020, 24:768 [Crossref], [Google scholar], [Publisher]
18
[19]. Berry J.O., Jones W.H., J. Soc. Pers. Relatsh., 1995, 12:463 [Crossref], [Google scholar], [Publisher]
19
[20]. Islam M.Z., Farjana S., Shahnaz R., Bangladesh J. Med. Sci., 2013, 12:74 [Google scholar], [Publisher]
20
[21]. Kilic D., Gencdogan B., Bag B., Arıcan D., Sex. Disabil., 2013, 31:287 [Crossref], [Google scholar], [Publisher]
21
[22]. Hsiao Y.-J., Higgins K., Pierce T., Whitby P.J.S., Tandy R.D., Res. Dev. Disabil., 2017, 70:152 [Crossref], [Google scholar], [Publisher]
22
[23]. Wicks-Nelson R., Israel A.C., The Developmental Psychopathology Perspective. Abnormal Child and Adolescent Psychology. Pearson New International Edition, Edinburg, 2014 [Google scholar], [Publisher]
23
[24]. Hardy J., Gwinn-Hardy K., Science, 1998, 282:1075 [Crossref], [Google scholar], [Publisher]
24
[25]. McConnell D., Savage A., Curr Dev Disord Rep. 2015, 2:100 [Crossref], [Google scholar], [Publisher]
25
[26]. Santoso D.Y.A., Mediastini E., Livana P.H., J. Ilmu Keperawatan Jiwa, 2020, 3:357 [Crossref], [Google scholar], [Publisher]
26
[27]. Hussain I., Warner M.D., Hallahan B., Ir. J. Psychol. Med., 2009, 26:69 [Crossref], [Google scholar], [Publisher]
27
[28]. Mubin M.F., Livana P.H., Enfermeria Clin., 2020, 30:155 [Google scholar], [Publisher]
28
[29]. Komala E.P.E., Keliat B.A., Wardani I.Y., Enfermeria Clin., 2018, 28:88 [Crossref], [Google scholar], [Publisher]
29
[30]. Dewi A.R., Daulima N.H.C., Wardani I.Y., Enfermeria Clin., 2019, 29:76 [Crossref], [Google scholar], [Publisher]
30
[31]. Swadi H., Bobier C., Price L., Craig B., Australas. Psychiatry, 2010, 18:53 [Crossref], [Google scholar], [Publisher]
31
[32]. Fristad M.A., Gavazzi S.M., Mackinaw-Koons B., Biol. Psychiatry, 2003, 53:1000 [Crossref], [Google scholar], [Publisher]
32
[33] Ericson S., Hesla M.W., Stadskleiv K., J. Intellect. Disabil., 2021, 15:1744629521995373 [Crossref], [Google scholar], [Publisher]
33
[34]. Ardic A., Cavkaytar A., Int. J. Early Child. Spec. Edu., 2019, 11:1 [Google scholar], [Publisher]
34
ORIGINAL_ARTICLE
The Effect of Video Education About Hypoglycemia on Knowledge of Diabetes Mellitus Patients
This study aimed to determine the effect of video education about hypoglycemia on knowledge of diabetes mellitus patients and their families. This type of research is a quantitative study with a pre-experiment method. This study was divided into two populations, namely the population of type 2 diabetes mellitus patients total of 162 people, and the families of diabetes mellitus patients total 162 people. In the population of diabetes mellitus patients, the sample used was 30 respondents who were divided into two groups, namely 15 respondents in the experimental group and 15 respondents in the control group. In the population of family diabetes mellitus patients, the sample used was 30 respondents, who were divided into 15 respondents for the experimental group and 15 respondents for the control group. The sampling technique was carried out by non-probability sampling with a purposive sampling technique. The results of the analysis using the paired t-test obtained a p-value of 0.001
https://www.jmchemsci.com/article_130415_a5494e336bc9ffe55fd371dc629807af.pdf
2021-05-01
267
278
10.26655/JMCHEMSCI.2021.3.7
Diabetes Mellitus
video education
purposive sampling technique
quantitative study
Okti
Purwanti
okti.sripurwanti@yahoo.com
1
School of Nursing, Faculty of Health Science, Universitas Muhammadiyah Surakarta, Indonesia, Jalan A Yani Pabelan, Kartasura Sukoharjo Indonesia
LEAD_AUTHOR
Puji
Nurani
shukribinbakar@gmail.com
2
School of Nursing, Faculty of Health Science, Universitas Muhammadiyah Surakarta, Indonesia, Jalan A Yani Pabelan, Kartasura Sukoharjo Indonesia. 57162
AUTHOR
Alia Ulfa
Wulandari
vahid.nourani1975@gmail.com
3
School of Nursing, Faculty of Health Science, Universitas Muhammadiyah Surakarta, Indonesia, Jalan A Yani Pabelan, Kartasura Sukoharjo Indonesia. 57162
AUTHOR
[1]. Soewondo P., Ferrario A., Tahapary D.L., Glob. Health, 2013, 9:1 [Crossref], [Google scholar], [Publisher]
1
[2]. Perwitasari D.A., Urbayatun S., Sage Open, 2016, 6:2158244016643748 [Crossref], [Google scholar], [Publisher]
2
[3]. Nugroho P.S., Tianingrum N.A., Sunarti S., Rachman A., Fahrurodzi D.S., Amiruddin R., Malays. J. Med. Health Sci., 2020, 16:126 [Google scholar]
3
[4]. Alisjahbana B., McAllister S.M., Ugarte-Gil C., Panduru N.M., Ronacher K., Koesoemadinata R.C., Zubiate C., Riza A.L., Malherbe S.T., Kleynhans L., Lopez S., Trans. R. Soc. Trop. Med. Hyg., 2020, 0:1 [Crossref], [Google scholar], [Publisher]
4
[5]. Saeedi P., Salpea P., Karuranga S., Petersohn I., Malanda B., Gregg E.W., Unwin N., Wild S.H., Williams R., Diabetes Res. Clin. Pract., 2020, 162:108086 [Crossref], [Google scholar], [Publisher]
5
[6]. Saeedi P., Petersohn I., Salpea P., Malanda B., Karuranga S., Unwin N., Colagiuri S., Guariguata L., Motala A.A., Ogurtsova K., Diabetes Res. Clin. Pract., 2019, 157:107843 [Crossref], [Google scholar], [Publisher]
6
[7]. Patterson C.C., Karuranga S., Salpea P., Saeedi P., Dahlquist G., Soltesz G., Ogle G.D., Diabetes Res. Clin. Pract., 2019, 157:107842 [Crossref], [Google scholar], [Publisher]
7
[8]. Federation I.D., IDF diabetes atlas 8th edition. International Diabetes Federation. 2017 [Google scholar], [Publisher]
8
[9]. Oldiara G.E., Aisyah R., Jatmiko S.W., Rosyidah D.U., Bestari R.S., Saintika Med. J. Ilmu Kesehat. Dan Kedokt. Kel., 2020, 16:115 [Crossref], [Google scholar], [Publisher]
9
[10]. Damayanti A., Tamtomo D., Indarto D., J. Health Promot. Behav., 2018, 3:139 [Crossref], [Google scholar], [Publisher]
10
[11]. Davies M.J., D’Alessio D.A., Fradkin J., Kernan W.N., Mathieu C., Mingrone G., Rossing P., Tsapas A., Wexler D.J., Buse J.B., Diabetes Care, 2018, 41:2669 [Crossref], [Google scholar], [Publisher]
11
[12]. American Diabetes Association. Diabetes Care, 2018, 41:S152
12
[13]. W Dogo D., Louis H., I Iliya N., U Ozioma A., T Aderemi A., Stware B., J. Med. Chem. Sci., 2019, 2:162 [Crossref], [Google scholar], [Publisher]
13
[14]. Edridge C.L., Dunkley A.J., Bodicoat D.H., Rose T.C., Gray L.J., Davies M.J., Khunti K., PloS One, 2015, 10:e0126427 [Crossref], [Google scholar], [Publisher]
14
[15]. Shriraam V., Mahadevan S., Anitharani M., Jagadeesh N.S., Kurup S.B., Vidya T.A., Seshadri K.G., Indian J. Endocrinol. Metab., 2015, 19:378 [Crossref], [Google scholar], [Publisher]
15
[16]. Li Q., Qin Y., Hu X., Li G., Ding H., Xiong X., Wang W., Sci. Rep., 2020, 10:1 [Crossref], [Google scholar], [Publisher]
16
[17]. Wardani A.K., Isfandiari M.A., J. Berk. Epidemiol., 2014, 2:1 [Google scholar], [Publisher]
17
[18]. Damanik E., Lubis R., Mutiara E., Int. J. Public Health Clin. Sci., 2020, 6:50 [Google scholar]
18
[19]. Luthfa I., Aspihan M., Lathif M.R., J. Ners, 2019, 14:327 [Crossref], [Google scholar], [Publisher]
19
[20]. Kurniati M.F., J. Nurs. Pract., 2019, 3:22 [Crossref], [Google scholar], [Publisher]
20
[21]. Hendrawati H., Afnuhazi R., Andayani R.P., Ahsan A., Purnamasari D., Eksakta Berk. Ilm. Bid. MIPA E-ISSN 2549-7464, 2021, 22:54 [Crossref], [Google scholar], [Publisher]
21
[22]. Rosyid F.N., Dharmana E., Suwondo A., HS K.H.N., Biomed. Pharmacol. J., 2018, 11:1413 [Crossref], [Google scholar], [Publisher]
22
[23]. Trisnawati S.K., Setyorogo S., J. Ilm. Kesehat., 2013, 5:6 [PDF], [Google scholar], [Publisher]
23
[24]. Kaplan H.I., Sadock B.,Jakarta: Bina Rupa Aksara, 2010, 113 [Google scholar], [Publisher]
24
[25]. Faswita W., Jurkessutra J. Kesehat. Surya Nusant., 2021, 9:146[Crossref], [Google scholar], [Publisher]
25
[26]. Khansa R.R., ARGIPA Arsip Gizi Dan Pangan, 2020, 5:66 [Crossref], [Google scholar], [Publisher]
26
[27]. Roifah I., J. Health Sci., 2017, 6:82 [Google scholar]
27
[28]. Rahayu N.W., Utami M.P.S., J. Ilmu Keperawatan Jiwa, 2018, 1:24 [Crossref], [Google scholar], [Publisher]
28
[29]. Purwanti O.S., Yetti K., Herawati T., 2016, 359 [PDF], [Google scholar], [Publisher]
29
[30]. Silbert R., Salcido-Montenegro A., Rodriguez-Gutierrez R., Katabi A., McCoy R.G., Curr. Diab. Rep., 2018, 18:1 [Crossref], [Google scholar], [Publisher]
30
[31]. Halajur U., Setiawan I., Int. J. Sci. Technol. Manag., 2021, 2:363 [Crossref], [Google scholar], [Publisher]
31
[32]. Ghannadi S., Amouzegar A., Amiri P., Karbalaeifar R., Tahmasebinejad Z., Kazempour-Ardebili S., J. Diabetes Res., 2016, 2016 [Crossref], [Google scholar], [Publisher]
32
[33]. Parik P.C., Patel V.J., Indian J. Endocrinol. Metab., 2019, 23:407 [Crossref], [Google scholar], [Publisher]
33
[34]. Rondhianto R., Nursalam N., Kusnanto K., Melaniani S., Ahsan A.A., J. Ners, 2019, 14:215 [Google scholar], [Publisher]
34
[35]. Kusnanto K., Sari N.P.W.P., Harmayetty H., Efendi F., Gunawan J., J. Taibah Univ. Med. Sci., 2018, 13:472 [Crossref], [Google scholar], [Publisher]
35
[36]. Kusnanto K., Ninuk D.K., Abu B., Erna D.W., Hidayat A., Syst. Rev. Pharm., 2020, 11:304 [PDF], [Google scholar], [Publisher]
36
[37]. Rafiee F., Abbasi Chaleshtari A., Kazemnejad L., Mahlouji Nia H., J. Med. Chem. Sci., 2021, 4:93 [Crossref], [Google scholar], [Publisher]
37
[38]. Dong J., Jian-yun Y., Dan-feng L., Chang-tai Z., Jian-ping Y., Yuan-qing P., Sci. Rep. Nat. Publ. Group, 2020, 10:20324[Crossref], [Google scholar], [Publisher]
38
[39]. Morris A.P., Voight B.F., Teslovich T.M., Ferreira T., Segre A.V., Steinthorsdottir V., Strawbridge R.J., Khan H., Grallert H., Mahajan A., Nat. Genet., 2012, 44:981 [Crossref], [Google scholar], [Publisher]
39
[40]. Oktorina R., Sitorus R., Sukmarini L., J. Endur. Kaji. Ilm. Probl. Kesehat., 2019, 4:171 [Crossref], [Google scholar], [Publisher]
40
[41]. Yamin A., Sari C.W.M., J. Keperawatan Padjadjaran, 2018, 6:175[Crossref], [Google scholar], [Publisher]
41
[42]. Notoatmodjo S., Jkt. Rineka Cipta, 2014:135 [Google scholar], [Publisher]
42
[43]. Shafiee G., Mohajeri-Tehrani M., Pajouhi M., Larijani B., J. Diabetes Metab. Disord., 2012, 11:1.
43
[44]. Vinik A.I., Vinik E., Am. J. Manag. Care, 2003, 9:S63 [Crossref], [Google scholar], [Publisher]
44
[45]. Bartha J.L., Martinez-Del-Fresno P., Comino-Delgado R., Eur. J. Obstet. Gynecol. Reprod. Biol., 2003, 109:41 [Crossref], [Google scholar], [Publisher]
45
[46]. Isnaningsih T., J. Teknol. Pembelajaran, 2021, 1:8 [PDF], [Google scholar], [Publisher]
46
[47]. Nu’im Haiya N., Ardian I., Marfu’ah S., J. Ners, 2020, 15:429
47
ORIGINAL_ARTICLE
Correlation between Factors Influencing Severe Disability in Cerebral Palsy and Obtained Physiotherapy
This study aims to determine what factors influence severe disability in children with cerebral palsy and their relationship to the therapeutic measures obtained. The research method is descriptive observational research to describe the factors that affect severe disabilities in children with cerebral palsy (CP) and correlated with the therapeutic measures obtained and statistical analysis used to test data correlation applying the Pearson product-moment. The results showed (1) factors that aggravate disability in persons with CP are comorbidities, severe degree of spasticity, primitive reflexes that have not been well integrated, (2) strong, positive, and significant correlation between the maturity of primitive reflexes and physiotherapy measures was obtained (r = 0.762, α = 0.000), (3) perfect, positive and significant correlation between the degree of the weight of spasticity and physiotherapy measures was obtained (r = 0.926, α = 0.000), and (4) strong, positive and significant correlation between levels of functional ability with physiotherapy measures was obtained (r = 0.773, α = 0.000). This research concludes that there is a correlation between factors that influence severe disability in cerebral palsy and obtained physiotherapy.
https://www.jmchemsci.com/article_130452_143ce8df5de544dd850d344de01c5148.pdf
2021-05-01
279
288
10.26655/JMCHEMSCI.2021.3.8
severe disability
Cerebral palsy
therapeutic measures
Disability
Physiotherapy
Bambang
Trisnowiyanto
bambang.trisnowiyanto@yahoo.com
1
Majors of Physiotherapy, Health Polytechnic of Surakarta, Indonesia
LEAD_AUTHOR
Budi
Utomo
shukribinbakar@gmail.com
2
Majors of Physiotherapy, Health Polytechnic of Surakarta, Indonesia
AUTHOR
[1]. Khuu S., Virgilio K.M., Fernandez J.W., Handsfield G.G., in Int. Symp. Comput. Methods Biomech. Biomed. Eng., Springer, 2019:142. [Crossref], [Google scholar], [Publisher]
1
[2]. Marret S., Vanhulle C., Laquerriere A., Handb. Clin. Neurol., 2013, 111:169 [Crossref], [Google scholar], [Publisher]
2
[3]. McIntyre S., Morgan C., Walker K., Novak I., Dev. Disabil. Res. Rev., 2011, 17:114 [Crossref], [Google scholar], [Publisher]
3
[4]. Colver A., Fairhurst C., Pharoah P.O.D., The Lancet, 2014, 383:1240 [Crossref], [Publisher]
4
[5]. Patel D.R., Neelakantan M., Pandher K., Merrick J., Transl. Pediatr., 2020, 9:S125 [Crossref], [Google scholar], [Publisher]
5
[6]. Gulati S., Sondhi V., Indian J. Pediatr., 2018, 85:1006 [Crossref], [Google scholar], [Publisher]
6
[7]. Fazal-ur-Rehman M., J. Med. Chem. Sci., 2019, 2:85 [Crossref], [Google scholar], [Publisher]
7
[8]. Latha N.L., Gyananath G., Kasa A., Zubaidha P.K., J. Med. Chem. Sci., 2019, 2:46 [Crossref], [Google scholar], [Publisher]
8
[9]. Zafeiriou D.I., Pediatr. Neurol., 2004, 31:1 [Crossref], [Google scholar], [Publisher]
9
[10]. Ko J., Kim M., Phys. Ther., 2013, 93:393 [Crossref], [Google scholar], [Publisher]
10
[11]. Harvey A.R., J. Physiother., 2017, 63:187 [Crossref], [Google scholar], [Publisher]
11
[12]. Bosdriesz J.R., Stel V.S., van Diepen M., Meuleman Y., Dekker F.W., Zoccali C., Jager K.J., Nephrology, 2020, 25:737 [Crossref], [Google scholar], [Publisher]
12
[13]. Simpson K.J., Moran M.T., Foster M.L., Shah D.T., Chung D.Y., Nichols S.D., McCall K.L., Piper B.J., BMJ Open, 2019, 9:e027117 [Crossref], [Google scholar], [Publisher]
13
[14]. Puzi A.A., Sidek S.N., Rosly H.M., Daud N., Yusof H.M., in IOP Conf. Ser. Mater. Sci. Eng., IOP Publishing, 2017, 260:012024 [Google scholar], [Publisher]
14
[15]. MacLennan A.H., Thompson S.C., Gecz J., Am. J. Obstet. Gynecol., 2015, 213:779 [Crossref], [Google scholar], [Publisher]
15
[16]. Pakula A.T., Braun K.V.N., Yeargin-Allsopp M., Phys. Med. Rehabil. Clin., 2009, 20:425 [Crossref], [Google scholar], [Publisher]
16
[17]. Trisnowiyanto B., Utomo B., J. Keterapian Fis., 2020, 5:1 [Crossref], [Google scholar], [Publisher]
17
[18]. Rosenbaum P., Paneth N., Leviton A., Goldstein M., Bax M., Damiano D., Dan B., Jacobsson B., Dev Med Child Neurol Suppl, 2007, 109:8 [PDF], [Google scholar], [Publisher]
18
[19]. Odding E., Roebroeck M.E., Stam H.J., Disabil. Rehabil., 2006, 28:183 [Crossref], [Google scholar], [Publisher]
19
[20]. Stavsky M., Mor O., Mastrolia S.A., Greenbaum S., Than N.G., Erez O., Front. Pediatr., 2017, 5:21 [Crossref], [Google scholar], [Publisher]
20
[21]. Jahnsen R., Villien L., Aamodt G., Stanghelle J.K., Holm, I., Adv. Physiother. 2003, 5:21 [Crossref], [Google scholar], [Publisher]
21
[22]. Kaya Kara O., Atasavun Uysal S., Turker D., Karayazgan S., Gunel M.K., Baltaci G., Dev. Med. Child Neurol., 2015, 57:81 [Crossref], [Google scholar], [Publisher]
22
[23]. Wagh S.C., Malawade M.R., Vardharajulu G., 2019, 9:8 [PDF], [Google scholar], [Publisher]
23
[24]. Arshad N., Imran M., Munir Z., Akram S., Hameed A.A., Prof. Med. J., 2018, 25:1546 [PDF], [Google scholar]
24
[25]. Jahnsen R., Villien L., Aamodt G., Stanghelle J.K., Holm I., Adv. Physiother., 2003, 5:21 [Crossref], [Google scholar], [Publisher]
25
ORIGINAL_ARTICLE
Ethnobotanical Survey of Medicinal Plants Used By the Marakwet Community in Cherangani Forest, Kenya
Since long time ago, humans have used medicinal plants. Currently, many of the contemporary drugs can be traced to plant origins. Human activities such as deforestation and farming risk the availability of medicinal plants of medical importance; therefore, there is a need to document knowledge and information on these plants. Structured questionnaires, which involved oral interviews and discussions, were used to gather information from the 35 selected herbalists. The information on every medicinal plant used in the treatment of human diseases was documented. A total of 26 medicinal plants were recorded with trees (38.5%), herbs (30.8%), shrubs (26.9%), and climbers (3.8%). The plant parts were either used singly or in combination. The mixture of leaves, roots, and barks were the most preferred combination by 77.1%, followed by barks and roots by 57.1%, and leaves and barks by 11.4%. The diseases treated were gastrointestinal ailments by 97.1%, while skin and respiratory were 80% each. Boiling was the most preferred method of preparation (58%), followed by burning to ashes (28%), boiling (12%), and raw (2%). Oral administration was the most preferred method (63%), followed by swabs (24%), and inhalation (13%). The medicinal plant's primary source was Cherangani forest (91.4%), although some herbalists had also domesticated some medicinal plants (8.6%). The study provides information on medicinal plants used by herbalists in the Marakwet community, which be used in investigating potential active compounds in the documented medicinal plants for the development of crude drugs.
https://www.jmchemsci.com/article_130626_d7d9e3159a5fb5908d491888cdeea758.pdf
2021-05-01
289
300
10.26655/JMCHEMSCI.2021.3.9
Cherangani forest
herbalists
medicinal plants
Mourine
Mutai
mourinejerono23@gmail.com
1
Department of Biochemistry, Microbiology and Biotechnology, School of Pure and Applied Sciences, Kenyatta University, Nairobi, Kenya
LEAD_AUTHOR
Ezekiel
Njeru
njeruezek@gmail.com
2
Department of Biochemistry, Microbiology and Biotechnology, School of Pure and Applied Sciences, Kenyatta University, Nairobi, Kenya
AUTHOR
Regina
Ntabo
rntabo@gmail.com
3
Department of Biochemistry, Microbiology and Biotechnology, School of Pure and Applied Sciences, Kenyatta University, Nairobi, Kenya
AUTHOR
[1]. World HealthOrganization WHO. WHO traditional medicine strategy: 2014-2023. 2013 [PDF], [Google scholar],
1
[2]. Horrigan B., Le Tourneau M., Altern. Ther. Health Med., 2003, 9:21 [Google scholar], [Publisher]
2
Hussain M.S., Fareed S., Ansari S., Rahman M.A., Ahmad I.Z., Saeed M., J. Pharm. Bioallied. Sci., 2012, 4:10 [Crossref], [Google scholar], [Publisher]
3
[3]. Popović Z., Matić R., Bojović S., Stefanović M., Vidaković V., J. Ethnopharmacol., 2016, 181:182 [Crossref], [Google scholar], [Publisher]
4
[4]. Maroyi A., Cheikhyoussef A., Indian j. tradit. knowl., 2015, 14:401 [PDF], [Google scholar], [Publisher]
5
[5]. Jiang H., Zhang Y., Lü E., Wang C., Veg. Hist. Archaeobot., 2015, 24:165 [Crossref], [Google scholar], [Publisher]
6
[6]. Ozioma E.O.J., Chinwe O.A.N., Herbal medicines in African traditional medicine. Herb. Med., 2019, 10:191 [Google scholar], [Publisher]
7
[7]. Elujoba A.A., Odeleye O.M., Ogunyemi C.M., African J. Tradit. Complement Altern. Med., 2005, 2:46 [Google scholar], [Publisher]
8
[8]. Gurib-Fakim A., Mol. Aspects Med., 2006, 27:1 [Crossref], [Google scholar], [Publisher]
9
[9]. Kigen G., Kipkore W., Wanjohi B., Haruki B., Kemboi J., Pharmacognosy Res., 2017, 9:333 [Crossref], [Google scholar], [Publisher]
10
[10]. Kipkore W., Wanjohi B., Rono H., Kigen G., J. Ethnobiol. Ethnomed., 2014, 10:24 [Crossref], [Google scholar], [Publisher]
11
[11]. Moore C.D., American Imperialism and the State, 1893-1921. Cambridge University Press; 2017 [Google scholar], [Publisher]
12
[12]. Salako K.V., Moreira F., Gbedomon R.C., Tovissodé F., Assogbadjo A.E., Kakaï R.L.G., J. Ethnobiol. Ethnomed., 2018, 14:36 [Crossref], [Google scholar], [Publisher]
13
[13]. Potvin C., Revéret J.P., Patenaude G., Hutton J., The role of indigenous peoples in conservation actions: a case study of cultural differences and conservation priorities. In: Governing Global Biodiversity. Routledge: 2017 [Google scholar], [Publisher]
14
[14]. Lovren V.O., Traditional and Indigenous Knowledge: Bridging Past and Future Sustainable Development. 2019 [Crossref], [Publisher]
15
[15]. Akotsi E.F.N., Changes in forest cover in Kenya’s five" water towers" 2003-2005. Kenya Forests Working Group; 2006 [Publisher]
16
[16]. Joana Gil‐Chávez G., Villa J.A., Fernando Ayala‐Zavala J., Basilio Heredia J., Sepulveda D., Yahia E.M., González‐Aguilar G.A., Compr. Rev. Food Sci. Food Saf., 2013, 12:5 [Crossref], [Google scholar], [Publisher]
17
[17]. Forest C.H., Strategic Ecosystem Management Plan 2015-2040. 2015 [PDF], [Google scholar]
18
[18]. Minja M., Allport R., Njau P. Tanzan Vet. J., 2001, 17:186 [Google scholar], [Publisher]
19
[19]. Miara M.D., Bendif H., Hammou M.A., Teixidor-Toneu I., J. Ethnopharmacol., 2018, 219:248 [Crossref], [Google scholar], [Publisher]
20
[20]. Eddouks M., Ajebli M., Hebi M., J. Ethnopharmacol., 2017, 198:516 [Crossref], [Google scholar], [Publisher]
21
[21]. Bouasla A., Bouasla I., Phytomedicine, 2017, 36:68 [Crossref], [Google scholar], [Publisher]
22
[22]. Beyene B., Beyene B., Deribe H., J. Resour. Dev. Manag., 2016, 22:33 [PDF], [Google scholar], [Publisher]
23
[23]. Kebebew M., Mohamed E., International J. Herb. Med., 2017, 5:124 [PDF], [Google scholar], [Publisher]
24
[24]. Cadena-González A.L., Sørensen M., Theilade I., J. Ethnobiol. Ethnomed., 2013, 9:23 [Crossref], [Google scholar], [Publisher]
25
[25]. Umair M., Altaf M., Abbasi A.M., PLoS One., 2017, 12:e0177912 [Crossref], [Google scholar], [Publisher]
26
[26]. Mbuni Y.M., Wang S., Mwangi B.N., Mbari N.J., Musili P.M., Walter N.O., Hu G., Zhou Y., Wang Q., Plants, 2020, 9:331 [Crossref], [Google scholar], [Publisher]
27
[27]. Madani S., Amel B., Noui H., Djamel S., Hadjer H., J. Intercult. Ethnopharmacol., 2017, 6:311 [Crossref], [Google scholar], [Publisher]
28
[28]. Aadhan K., Anand S.P., Int. J. Herb. Med., 2017, 5:17 [PDF], [Google scholar], [Publisher]
29
[29]. Nafiu M.O., Hamid A.A., Muritala H.F., Adeyemi S.B., Preparation, standardization, and quality control of medicinal plants in Africa. In: Medicinal Spices and Vegetables from Africa. Elsevier; 2017. p. 171 [Crossref], [Google scholar], [Publisher]
30
[30]. Yatoo M.I., Saxena A., Gopalakris A., Alagawany M., Dhama K., Int. J. Pharmacol., 2017, 13:732 [Crossref], [Google scholar], [Publisher]
31
[31]. Ganie A.H., Tali B.A., Nawchoo I.A., Khuroo A.A., Reshi Z.A., Dar G.H., Diversity in medicinal and aromatic flora of the Kashmir Himalaya. In: Biodiversity of the Himalaya: Jammu and Kashmir State. Springer; 2020 [Crossref], [Google scholar], [Publisher]
32
ORIGINAL_ARTICLE
Investigation of Allergenic and Mutagenic Effects of Phenolic Compound, an Arignase-2 Inhibitor
A big risk factor for sensitization and allergic diseases is susceptibility to animal allergens. The most significant animal allergens are derived from mammals, besides mites and cockroaches. The experiments on the allergenic properties of KUD975 were carried out on bisexual sexually mature albino guinea pigs weighing 300 ± 20 g. During the initial assessment of allergenic and mutagenic properties, the allergenic properties of KUD975 were studied by setting up an active skin anaphylaxis reaction. Mutagenicity in the test of induction of dominant lethal mutations was studied. For research, outbred male rats weighing 180-220 g KUD975 was administered intragastrically at a dose of 106 mg/kg, which corresponds to a 40-fold estimated therapeutic dose. Planting intact females at the rate of 3 heads for each male was performed weekly according to the stages of spermatogenesis. The study of the allergenic effect in the formulation of the reaction of active skin anaphylaxis in guinea pigs and mutagenicity in the test for the induction of dominant lethal mutations of the phenolic compound methyl ester (2 - ((1-hydroxy naphthalene-2-yl) thio) acetyl) -D-proline under the laboratory code KUD975 showed no signs of allergenicity and mutagenicity of compound KUD975. Given the results of this study, as well as the previously conducted study of toxicological safety, pharmacological activity, methyl ester (2 - ((1-hydroxy naphthalene-2-yl) thio) acetyl) -D-proline KUD-975 can be recommended for further study as a medicinal agent acting on arignase-2 for the treatment and prevention of a number of endothelium-associated diseases.
https://www.jmchemsci.com/article_130832_3b05fc7fbc5569281114bd09c17e37c9.pdf
2021-05-01
301
307
10.26655/JMCHEMSCI.2021.3.10
Endothelial disfunction
arginase2
Thrombin
arterial hypertension
Allergenicity
Mutagenicity
Phenolic compound
Liliya V.
Korokina
liliya.korokina@yahoo.com
1
Belgorod State University, 85, Pobedy St., Belgorod, 308015, Russia
LEAD_AUTHOR
Mikhail V.
Pokrovskii
shukribinbakar@gmail.com
2
Belgorod State University, 85, Pobedy St., Belgorod, 308015, Russia
AUTHOR
Indira S.
Kochkarova
fominadaniel@gmail.com
3
Belgorod State University, 85, Pobedy St., Belgorod, 308015, Russia
AUTHOR
Olga N.
Pokopeiko
vahid.nourani1975@gmail.com
4
Belgorod State University, 85, Pobedy St., Belgorod, 308015, Russia
AUTHOR
Sergey V.
Povetkin
irinakrish2000@gmail.com
5
Belgorod State University, 85, Pobedy St., Belgorod, 308015, Russia
AUTHOR
[1]. Hameed A., Fatima G.R., Malik K., Muqadas A., Fazal-ur-Rehman M., J. Med. Chem. Sci., 2019, 2:9 [Crossref], [Google scholar], [Publisher]
1
[2]. Adejoke H.T., Louis H., Amusan O.O., Apebende G., J. Med. Chem. Sci., 2019, 2:130 [Crossref], [Google scholar], [Publisher]
2
[3]. Bertoni A., Mota-Rojas D., Álvarez-Macias A., Mora-Medina P., Guerrero-Legarreta I., Morales-Canela A., Gómez-Prado J., José-Pérez N., Martínez-Burnes J., J. Anim. Behav. Biometeorol., 2020, 8:288 [Crossref], [Google scholar], [Publisher]
3
[4]. Furchgott R.F., Zawadzki J.V., nature, 1980, 288:373 [Crossref], [Google scholar], [Publisher]
4
[5]. Flammer A.J., Lüscher T.F., Pflüg. Arch.-Eur. J. Physiol., 2010, 459:1005 [Crossref], [Google scholar], [Publisher]
5
[6]. Flammer A.J., Anderson T., Celermajer D.S., Creager M.A., Deanfield J., Ganz P., Hamburg N.M., Lüscher T.F., Shechter M., Taddei S., Circulation, 2012, 126:753 [Crossref], [Google scholar], [Publisher]
6
[7]. Virdis A., Ghiadoni L., Taddei S., Pflüg. Arch.-Eur. J. Physiol., 2010, 459:1015 [Crossref], [Google scholar], [Publisher]
7
[8]. Bonetti P.O., Lerman L.O., Lerman A., Arterioscler. Thromb. Vasc. Biol., 2003, 23:168 [Crossref], [Google scholar], [Publisher]
8
[9]. Shabrov A.V., Apresyan A.G., Dobkes A.L., Ermolov S.U., Ermolova T.V., Manasyan S.G., Serdyukov S.V., Med. Acad. J., 2017, 17:7 [Crossref], [Google scholar], [Publisher]
9
[10]. Chumasov E.I., Petrova E.S., Adv. Gerontol., 2020, 10:266 [Crossref], [Google scholar], [Publisher]
10
[11]. Potočnjak I., Gobin I., Domitrović R., Phytother. Res., 2018, 32:1090 [Crossref], [Google scholar], [Publisher]
11
[12]. Trindade G.G., Thrivikraman G., Menezes P.P., França C.M., Lima B.S., Carvalho Y.M., Souza E.P., Duarte M.C., Shanmugam S., Quintans-Júnior L.J., Food Chem. Toxicol., 2019, 125:198 [Crossref], [Google scholar], [Publisher]
12
[13]. Elbe H., Yigitturk G., Cavusoglu T., Baygar T., Ozgul Onal M., Ozturk F., Ultrastruct. Pathol., 2020, 44:193 [Crossref], [Google scholar], [Publisher]
13
[14]. Günes-Bayir A., Kiziltan H.S., Kocyigit A., Güler E.M., Karataş E., Toprak A., Anticancer. Drugs, 2017, 28:522 [Crossref], [Google scholar], [Publisher]
14
[15]. Boudiaf F., Chouba I., Amri N., Tahraoui A., J. Anim. Behav. Biometeorol., 2020, 8:190 [Crossref], [Google scholar], [Publisher]
15
[16]. Morton L.W., Caccetta R.A.-A., Puddey I.B., Croft K.D., Clin. Exp. Pharmacol. Physiol., 2000, 27:152 [Crossref], [Google scholar], [Publisher]
16
[17]. Rodríguez-Calzada T., Qian M., Strid AAke, Neugart S., Schreiner M., Torres-Pacheco I., Guevara-González R.G., Plant Physiol. Biochem., 2019, 134:94 [Crossref], [Google scholar], [Publisher]
17
[18]. Chung I.M., Lim J.J., Ahn M.S., Jeong H.N., An T.J., Kim S.H., J. Ginseng Res., 2016, 40:68 [Crossref], [Google scholar], [Publisher]
18
[19]. Aliev G., Palacios H.H., Lipsitt A.E., Fischbach K., Lamb B.T., Obrenovich M.E., Morales L., Gasimov E., Bragin V., Neurotox. Res., 2009, 16:293 [Crossref], [Google scholar], [Publisher]
19
[20]. Gielis J.F., Lin J.Y., Wingler K., Van Schil P.E., Schmidt H.H., Moens A.L., Free Radic. Biol. Med., 2011, 50:765 [Crossref], [Google scholar], [Publisher]
20
[21]. Kudryavtsev K.V., Korokin M.V., Gudyrev O.S., 2017, 3:10 [Crossref], [Google scholar], [Publisher]
21
[22]. Elagin V.V., Bratchikov O.I., Zatolokina M.A., Res. Results Pharmacol., 2018, 4:29 [Crossref], [Google scholar], [Publisher]
22
[23]. Severinova O.V., Gureev V.V., Zhilinkova L.A., Lazareva G.A., Gureeva A.V., Lazareva S.S., Res. Results Pharmacol., 2019, 5:47 [Crossref], [Google scholar], [Publisher]
23
[24]. Pacher P., Beckman J.S., Liaudet L., Physiol. Rev., 2007, 87:315 [Crossref], [Google scholar], [Publisher]
24
[25]. Schmitt C.A., Dirsch V.M., Nitric Oxide, 2009, 21:77 [Crossref], [Google scholar], [Publisher]
25
[26]. Steppan J., Nyhan D., Berkowitz D., Front. Immunol., 2013, 4:278 [Crossref], [Google scholar], [Publisher]
26
[27]. Minozzo B.R., Fernandes D., Beltrame F.L., Planta Med., 2018, 84:277 [Crossref], [Google scholar], [Publisher]
27
[28]. Korokina L.V., Pokrovskii M.V., Korokin M.V., Pokopejko O.N., Pokrovskaia T.G., Galenko-Yaroshevsky P.G., Dolzhikov A.A., Reznichenko L.V., Yakovleva E.G., Int. J. Pharm. Res., 2019, 11:1608 [Crossref], [Google scholar], [Publisher]
28
[29]. Korokina L.V., Pokrovskii M.V., Korokin M.V., Pokopejko O.N., Pokrovskaia T.G., Galenko-Yaroshevsky P.G., Dolzhikov A.A., Reznichenko L.V., Yakovleva E.G., 2019 , 46:258 [Google scholar], [Publisher]
29
[30]. Pokrovskii M., Korokin M., Kudryavtsev K., Pokrovskaya T., Gudyrev O., Gureev V., Korokina L., Povetkin S., Bull. Exp. Biol. Med., 2017, 163:436[Crossref], [Google scholar], [Publisher]
30
[31]. Severinova O.V., Lokteva T.I., Gureev V.V., Zhernakova N.I., Osipova O.A., Dolzhikov A.A., Pokrovskaya T.G., 2019, 46:272 [Google scholar], [Publisher]
31