eng
Sami Publishing Company (SPC)
Journal of Medicinal and Chemical Sciences
2651-4702
2018-10-01
1
2
26
27
10.26655/jmchemsci.2018.9.1
63166
K2CO3/CS2: A mild and effiecint system for the prapartion of trithiocarbonates
Issa Amini
issaamini5548@gmail.com
1
Sarvin Mohammadi-Aghdam
sarvin.s108@gmail.com
2
Faten Divsar
divsar@gmail.com
3
Department of Chemistry, Payame Noor University, PO BOX 19395-4697 Tehran, Iran
Department of Chemistry, Payame Noor University, PO BOX 19395-4697 Tehran, Iran
Department of Chemistry, Payame Noor University, PO BOX 19395-4697 Tehran, Iran
A mild and efficient one-pot protocol for the preparation of symmetrical trithiocarbonates using potassium carbonate and carbon disulfide in DMF has been developed. This protocol is mild and efficient compared to other reported methods.A mild and efficient one-pot protocol for the preparation of symmetrical trithiocarbonates using potassium carbonate and carbon disulfide in DMF has been developed. This protocol is mild and efficient compared to other reported methods.
https://www.jmchemsci.com/article_63166_b6957a9d358ad127680079eb5a312693.pdf
Trithiocarbonates
Potassium carbonate
Carbon disulfide
One-pot
eng
Sami Publishing Company (SPC)
Journal of Medicinal and Chemical Sciences
2651-4702
2018-10-01
1
2
28
30
10.26655/jmchemsci.2018.9.2
65058
مقاله پژوهشی
Biosynthesis of Iron Oxide Nanoparticles by Cytoplasmic Extract of Bacteria Lactobacillus Fermentum
Mina Fani
mina.fani2016@yahoo.com
1
Fereshte Ghandehari
ghandehari@iaufala.ac.ir
2
Malahat Rezaee
malahatrezaee@gmail.com
3
Department of Microbiology, Falavarjan Islamic Azad University, Isfahan, Iran
Department of Microbiology, Falavarjan Islamic Azad University, Isfahan, Iran
Department of Biochemistry, Falavarjan Islamic Azad University, Isfahan, Iran
In the past decade, the attention of science and technology has focused on production of nanoparticles. There are various ways for synthesizing of nanoparticles that many of them are not cost effective due to power and material consumption. Therefore, production of nanoparticles through biologic ways is needed. For this purpose, different biological structures such as plants, algae, and microorganisms such as bacteria, string molds, and yeasts are used for nanoparticles production. This study is focused on biosynthesis of iron oxide nanoparticles by cytoplasmic extracts of bacteria Lactobacillus Fermentum, which is a probiotic microorganism, based on the method of green chemistry. After preparation of cytoplasmic extract of bacteria Lactobacillus Fermentum through freez-thow method, iron sulfate solution (III) with a concentration of 10-3 M was added in an equal volume ratio (V / V% 10) and incubated for 3 weeks at 37 ° C in the presence of 5% carbon dioxide. Production of nanoparticles was investigated by X-ray Diffraction (XRD) and Transmission Electron Microscopy (TEM). Changing the color of solution to black is an indication of iron sulfate nanoparticles production. The formation of iron oxide nano crystals by Lactobacillus Fermentum cytoplasmic extract was shown by XRD analysis. The average nanoparticles sizes as determined by transmission electron microscopy (TEM) were found to be about 10-15 nm with a spherical shape. Using Lactobacillus fermentum cytoplasmic extract can be considered as an efficient biological method for the production of iron oxide nanoparticles .In addition to be environmentally friendly, this method is cost effective.
https://www.jmchemsci.com/article_65058_db943a48a3272e9c6212b56b669fe954.pdf
Iron Oxide Nanoparticles
Lactobacillus Fermentum
biosynthesis of nanoparticles
Probiotic
eng
Sami Publishing Company (SPC)
Journal of Medicinal and Chemical Sciences
2651-4702
2018-10-01
1
2
31
32
10.26655/jmchemsci.2018.9.3
65057
مقاله پژوهشی
A density functional theory study on the effect of size on the ionization potential of different carbon fullerenes
Ali Mirzaie
a.mirzaie@gmail.com
1
Young Researchers and Elite Club, Ilam Branch, Islamic Azad University, Ilam, Iran
Theoretical investigations were performed to study the structures and properties of different carbon nanoclusters. The computed properties were compared with those of the fullerene. The study systems included carbon fullerenes C20, C26, C28 and ionization potential of studied fullerenes are reported and compared with those of the fullerenes. It was found that the computed electronic properties are significantly influenced by the shape and size of different carbon nanoclusters.
https://www.jmchemsci.com/article_65057_cabb5298ba5001e4a9a01ffd61de0c3f.pdf
Fullerenes
Ionization
Potential
eng
Sami Publishing Company (SPC)
Journal of Medicinal and Chemical Sciences
2651-4702
2018-10-01
1
2
33
35
10.26655/jmchemsci.2018.9.4
66449
مقاله پژوهشی
Efficient and Alternative Characterization of transition aluminas (η, γ, ϴ, δ-Al2O3) Derived from Aeroxide: Application of FT-IR and SEM
Isah Shehu
1
Delaware State University, Dover DE 19901, USA
Heat treatment of Aeroxide (Alu C) at 500 oC in high vacuumproduced reactive phase onaluminum oxide surface. While Aeroxide from Degussa shows a mixture of transition aluminas (γ, δ, and ϴ) phases, precise understanding on the development, surface morphology and microstructure of this catalytically active Al2O3 are not readily available. Combination of scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDS) and Fourier transform infra-red (FTIR) spectroscopy were used in this study to probe the transition alumina phase induced at the high temperature calcination. Assignment of IR bands on the pretreated sample at 500 oC unambiguously distinguished Θ-Al2O3 phase which is a mixture of tetrahedral and octahedral Al3+ sites on the face centered cubic (fcc) Oxygen sub lattice.
https://www.jmchemsci.com/article_66449_cfe306c8fbd7abf570abdfa680fc9915.pdf
Aeroxide
Transition aluminas
Scanning electron microscopy
Energy dispersive X-ray analysis
Fourier transform infrared spectroscopy
eng
Sami Publishing Company (SPC)
Journal of Medicinal and Chemical Sciences
2651-4702
2018-10-01
1
2
36
40
10.26655/jmchemsci.2018.9.5
66453
مقاله پژوهشی
RP-HPLC Method Development and Validation for the Quantitative Estimation of Mirabegron in Extended-Release Tablets
Ali Ramazani
aliramazani@gmail.com
1
Mehdi Rezaei
mehdirezaei.chem@yahoo.com
2
Department of Chemistry, University of Zanjan, P.O. Box: 45195-313, Zanjan, Iran
Department of Chemistry, University of Zanjan, P.O. Box: 45195-313, Zanjan, Iran
In this study, we describe and validate a rapid and sensitive method for constitution of Mirabegron in the Extended-Release tablets by RP-HPLC. The assay method by HPLC was found to be linear in the concentration range of 10 to 100 µg/mL. Successful separation was achieved by isocratic elution on a Restek C18 column (250 mm × 4.6 mm, 5μm). The mobile phase was composed of buffer pH: 7.0 potassium dihydrogen phosphate and acetonitrile (60:40 v/v) at the flow rate of 1 mL/min using UV detection at 249 nm, column oven temperature 45ºC and injection volume 10 𝜇L. The analytical results were validated by recovery studies. The percentage recovery method was found to be 99.00-101.17%. The LOD and LOQ were found to 0.015 μg/mL and 0.049 μg/mL. All the parameters of validation were in the acceptable range. This developed method was successfully applied for estimate the amount of Mirabegron in the tablets.
https://www.jmchemsci.com/article_66453_6acfd568778627a1c08720db7d7c152e.pdf
Mirabegronو Validationو RP-HPLCو Method Development
eng
Sami Publishing Company (SPC)
Journal of Medicinal and Chemical Sciences
2651-4702
2018-10-01
1
2
41
44
10.26655/jmchemsci.2018.9.6
68168
مقاله پژوهشی
Triterpenoid Saponins from the Stem Bark of Xeromphis nilotica (Rubiaceae)
Ibrahim Adam
moniter123@outlook.com
1
Iman Omer
yangcx@nwnu.edu.cn
2
Hu Yu-Lai
huyl@nwnu.edu.cn
3
Department of basic sciences, Faculty of Agriculture, University of Zalingei, Zalingei, Sudan
College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, People’s Republic of China
College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, People’s Republic of China
Two new triterpenoid saponins, named, 3-O-β-D-glucopyranosyl (1→3)-Olean-12-ene-19, 23-diol 1 and 3-O-{O-α-L-rhamno-pyranosyl-(1→3)-O-[-O-β-D-glucopyranosyl-(1→3)]-β-D-gluco-pyranosyl}-pomolic acid were isolated from the stem bark of Xeromphis nilotica through extensive chromatographic technique [TLC and CC] and their structures were elucidated on the basis of their spectral data [1D, 2D NMR and HR-ESI-MS] and chemical evidence.
https://www.jmchemsci.com/article_68168_ea9976a2bf1a67a4aded368643e2746f.pdf
Xeromphis nilotica
Triterpene saponines
Structural elucidation
Chemical evidence