@article { author = {Huang, Wenqin and Yang, Yuhui}, title = {Harmony (和): Concepts and Practice of Health in Confucius Philosophy Provided for People with Diseases}, journal = {Journal of Medicinal and Chemical Sciences}, volume = {4}, number = {5}, pages = {411-415}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2651-4702}, eissn = {2651-4702}, doi = {10.26655/JMCHEMSCI.2021.5.1}, abstract = {The concepts and practices of health in Confucius philosophy may provide patients with a possible way to dealing with life. This study aimed at exploring Confucius's understanding of health, good life, and well-being related to harmony. Documentation analysis was used to examine the meaning of health-related to harmony in Confucius philosophy. A qualitative approach was employed to identify concepts and practices regarding harmony. This research revealed Confucius's understanding of health, good life, and well-being based on harmony, which may provide a life philosophy to patients, a new perspective on living with illness, and offers a possible way for patients to deal with challenges.}, keywords = {Harmony,Confucius philosophy,people with diseases,Health}, url = {https://www.jmchemsci.com/article_133977.html}, eprint = {https://www.jmchemsci.com/article_133977_c6c45027a41a9b0af545d8c26be98ceb.pdf} } @article { author = {Ebrahimi Shah-Abadi, Mehran and Heydari, Mahdi and Goroei Sardu, Ehsan}, title = {Evaluation of Medicinal and Medical Effects on Quality of Life in Patients with Hyperthyroidism Due to Graves´ Disease}, journal = {Journal of Medicinal and Chemical Sciences}, volume = {4}, number = {5}, pages = {416-425}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2651-4702}, eissn = {2651-4702}, doi = {10.26655/JMCHEMSCI.2021.5.2}, abstract = {Different observational studies and randomized trials attempted to show advantages as well as limitations of surgical approaches for improvement in patients’ quality of life (QOL) suffering hyperthyroidism caused by the Graves´ disease (GD). We aimed to systematically examine the impact of surgery (thyroidectomy) on different components of QOL in patients with GD. Two reviewers began to deeply search the various databases of article published including Medline, Web of knowledge, Google Scholar, Scopus, and Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library for all eligible studies in accordance with the considered keywords. In final, seven articles were eligible for the final analysis that published between 2012 and 2019. The Comprehensive Meta-Analysis Software was employed for analysis. Assessing the level of quality of life using SF-36 tool showed significantly increase in both physical component score (weighted mean differences of 0.428, p <0.001) and psychological component score (weighted mean differences of 0.277, p <0.001) postoperatively compared with the baseline values. The assessment of QOL using the Thy PRO questionnaire also showed significantly improvement in total QOL score after surgery compared with before that (weighted mean differences of -1.466, p <0.001). We revealed considerably improving both physical and mental aspects of QOL following surgery in Graves’ disease.  }, keywords = {Quality of Life,hyperthyroidism,thyroidectomy,Meta-analysis}, url = {https://www.jmchemsci.com/article_134263.html}, eprint = {https://www.jmchemsci.com/article_134263_ea5aa0b947bf49634fde1b2b3957e0ea.pdf} } @article { author = {Ma, Yuaner and Jabar, Juhaini}, title = {The Chinese Private Medical Service Providers: A Review}, journal = {Journal of Medicinal and Chemical Sciences}, volume = {4}, number = {5}, pages = {426-433}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2651-4702}, eissn = {2651-4702}, doi = {10.26655/JMCHEMSCI.2021.5.3}, abstract = {In the past 20 years, the number of private medical institutions in China has increased rapidly, the technology has been upgraded and the scale has been expanded. Domestic medical service giants, specialty chains, international medical and diversified institutions have entered the private sector. The trend of value-based healthcare is emerging. The diversified pattern of running hospitals has taken shape. The global trend of value-based healthcare has also brought opportunities for differentiated development of private medical institutions in China, which promotes the transformation from "quantitative change" to "qualitative change". The influx of diversified social capital helps the expansion and integration of medium and high-end private hospitals. The investment in private hospitals and public hospitals in China's capital market has shown unprecedented growth; the diversified capital structure composed of investment institutions, pharmaceutical groups, insurance funds and pharmaceutical-related industrial chain enterprises has become the core driving force for the sustainable development of China's private medical institutions.}, keywords = {Chinese,private medical service,public hospitals and review}, url = {https://www.jmchemsci.com/article_134414.html}, eprint = {https://www.jmchemsci.com/article_134414_daae7a9700c458dc0c09290d0194ffb7.pdf} } @article { author = {Danesh, Hoseinali and Motaharian, Elham Sadat and Alimoradzadeh, Raheleh and Masoudi, Alireza and Taebi, Mozhgan}, title = {A Review of Laboratory Studies in COVID-19 in Different Patients}, journal = {Journal of Medicinal and Chemical Sciences}, volume = {4}, number = {5}, pages = {434-443}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2651-4702}, eissn = {2651-4702}, doi = {10.26655/JMCHEMSCI.2021.5.4}, abstract = {The aim of the present study was to review the laboratory studies in COVID 19 in different patients. The outbreak of Coronavirus 2019 (COVID-19) appeared in Wuhan, China, and the reason for its increasing spread is not fully understood. According to research, COVID-19 virus, like other risk factors in any country, has many heterogeneous effects, especially in the field of environment and energy. The clinical symptoms of this disease are nonspecific and cannot be easily distinguished from other acquired pneumonias. Therefore, radiological findings and laboratory tests play an important role in the diagnosis and follow-up of the disease. Preliminary studies have shown that people with underlying diseases are at higher risk for complications and mortality from COVID-19. Approximately 50% of hospitalized patients suspected of having a new coronavirus have other chronic diseases, and about 40% of hospitalized patients with confirmed new SARS-CoV-2 infection have heart disease. They are vascular or cerebrovascular. The researchers have also found a large difference in mortality by age group.}, keywords = {Covid Virus 19,Radiology,Disease,Clinical signs}, url = {https://www.jmchemsci.com/article_135018.html}, eprint = {https://www.jmchemsci.com/article_135018_cba1ec3be261e018a88b2c618cb8a432.pdf} } @article { author = {Adhikari, Subrato and Mandal, Anirban and Guha, Sriparna}, title = {Place Attachment and Decisions to Move: A Study of Indian Migrants during Covid-19 Pandemic and Directions to Future Research}, journal = {Journal of Medicinal and Chemical Sciences}, volume = {4}, number = {5}, pages = {444-451}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2651-4702}, eissn = {2651-4702}, doi = {10.26655/JMCHEMSCI.2021.5.5}, abstract = {The relation between attachment to places and human mobility are not straightforward or linear, but is frequently indirect and mediated by social, cultural and economic drivers. Migration affects people positively, but most migratory movement are due to economic issue, financial problem, unemployment, vulnerability, stress or shocks. This migratory movement has a place attachment angle that is now becoming increasingly noticed for several times. Place attachments are based on interpersonal interaction and can alter a person's perception of risk and coping techniques in areas prone to natural disasters. The COVID-19 pandemic had a significant impact on migrants. The interplay of COVID-19 and the decline in economic activity have led to both domestic and international instability. Due to environmental change, migration explains complex interactions, hazards and unpredictability. This study examines the problems and opportunities in terms of place for the immobile population that undergo environmental degradation and clarifies its significance in the pandemic situation in Indian context. }, keywords = {Place Attachment,migration,COVID-19,New Normal}, url = {https://www.jmchemsci.com/article_135058.html}, eprint = {https://www.jmchemsci.com/article_135058_b49012f77f45fa1450f4e5cf3f50b700.pdf} } @article { author = {Skvortsova, Maria}, title = {Molecular Graphs and Molecular Hypergraphs of Organic Compounds: Comparative Analysis}, journal = {Journal of Medicinal and Chemical Sciences}, volume = {4}, number = {5}, pages = {452-465}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2651-4702}, eissn = {2651-4702}, doi = {10.26655/JMCHEMSCI.2021.5.6}, abstract = {Computer chemistry is a field of science appearing at the intersection of chemistry, mathematics and informatics. For the solution of any task in this field some mathematical representation of chemical structures is need. The most widely used approach to description of molecular structure is based on its representation as a graph G with vertices and edges corresponding to atoms and bonds of molecule. However, there may be other ways of describing the molecular structure. In this paper a number of methods to present the molecular structures of organic compounds (hydrocarbons) as hypergraphs Hk (k=1,2,…) of special type is suggested. Some results of comparison of graph and hypergraph molecular models are also given. Construction of Hk is defined by neighborhoods of k-th order for all vertices in a graph G corresponding to the carbon skeleton of molecule (k=1,2,…). Besides, analytical formulae, expressing the adjacency matrices of Hk throw adjacency matrix of corresponding graph G are obtained (k=1,2,…). The comparison of traditional graph model G and suggested hypergraph models Hk (k=1,2,…) is made by definite quantitative parameters, characterizing the efficiency of their applications in some tasks of computer chemistry. Some 4 different sets of structural formulae of hydrocarbons and 30 different quantitative parameters are used for these investigations. It is shown, that in 97% of all considered 120 cases the model H1 is superior to the model G, and in other cases these models are equivalent. However, the models Hk for k ≥ 2 are worse than G and H1. It is also shown on concrete examples, that in some cases, H1-models may be useful in constructing the structure-property correlations, since their use allows us to obtain more precise correlations than for G-models (in 75% of considered cases).}, keywords = {Molecular Graph,Molecular hypergraph,Graph invariants,Hypergraph invariants,Structure-property correlations}, url = {https://www.jmchemsci.com/article_135204.html}, eprint = {https://www.jmchemsci.com/article_135204_c7d2f16e4f9ce79aa7eb6691e472049f.pdf} } @article { author = {Seypilov, Azamat Aidarbekovich and Akhmetzhanova, Elina Ansarovna and Outlev, Kazbek Medzhidovich and Kruchinin, Evgeny Viktorovich and Kostenko, Ivan Vyacheslavovich}, title = {Metabolic Changes after the Surgical Treatment of Morbid Obesity}, journal = {Journal of Medicinal and Chemical Sciences}, volume = {4}, number = {5}, pages = {466-471}, year = {1999}, publisher = {Sami Publishing Company (SPC)}, issn = {2651-4702}, eissn = {2651-4702}, doi = {10.26655/JMCHEMSCI.2021.5.7}, abstract = {The use of bariatric surgery in the treatment of morbid obesity is most effective for metabolic syndrome. The greatest decrease in body weight occurred in the first 3 months after intragastric balloon and biliopancreatic diversion, whereas with a laparoscopic adjustable gastric band, the best effect was observed in the period from 3 months to 1 year. With an intragastric balloon, a decrease in body weight of 6.6% was observed in the first 3 months and 13.5% after 6 months, with an average decrease in body mass index of 5.7±2.3 kg/m2. After a laparoscopic adjustable gastric band, there was a 14.1% decrease in body weight at 3 months, a 21.4% decrease at 6 months, and a 27.9% decrease in body mass index at 1 year, with a 13.3±2.5 kg/m2 decrease in body mass index. Considering intragastric balloon surgery, as early as 6 months after balloon removal, almost 33% of patients showed regain of initial body weight, and 1 year later – almost 50% of patients. It should be noted only after a laparoscopic adjustable gastric band and biliopancreatic diversion, 3 months after the operation with preservation of results 1 year after treatment, a significant reduction of systolic and diastolic blood pressure and levels of total cholesterol and low-density lipoproteins was observed. If the body mass index is over 50 kg/m2 and the metabolic syndrome is present, biliopancreatic diversion surgery is the best option also for the treatment of carbohydrate and lipid metabolism disorders, blood pressure regulation, and other diseases associated with obesity.}, keywords = {Bariatric surgery,Carbohydrate metabolism disorder,Lipid metabolism disorder,Metabolic Syndrome,Morbid obesity}, url = {https://www.jmchemsci.com/article_135251.html}, eprint = {https://www.jmchemsci.com/article_135251_c53e9f098bb3fac4b5487ebba0de9c7a.pdf} } @article { author = {Rozantsev, Anatoly I. and Malko, Igor V. and Antipov, Alexey O. and Antipov, Oleg V. and Evseev, Eugene Yu.}, title = {Improving the Traction and Adhesion Properties of Nano Water Sprinkling Machines Fregat in Areas with Rugged Terrain}, journal = {Journal of Medicinal and Chemical Sciences}, volume = {4}, number = {5}, pages = {472-483}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2651-4702}, eissn = {2651-4702}, doi = {10.26655/JMCHEMSCI.2021.5.8}, abstract = {In recent years, nanotechnology has been considered a useful technology for agriculture and has been studied in the fields of water management and crop production and the use of nanotechnology in crop breeding, production, and plant protection methods. In comparison with other agricultural machinery, Nano water sprinkling machines Fregat has more difficult working conditions in terms of rutting and traction-adhesion properties due to reduced bearing capacity of wetted soils, long sprinkling machine lengths, and irrigated areas with a wide range of strength and relief characteristics. Therefore, the most important in improving multi-support sprinkling machines is, first of all, the study of the soil-relief conditions of irrigated lands and their influence on the technological and technical ways of solving the problem of its soil trafficability. Also important is the issue of adhesion of the undercarriage systems of the sprinkling machine bogies. Fregat sprinkling machine DMU-B-463-90 was used in the Lukhovitsky District of the Moscow Region. The stuhollow punchs were carried out on soddy podzolic medium loamy soils. Cleaning devices for undercarriage systems providing wheel cleaning have been proposed. According to industrial research data obtained in production conditions, all high-quality operational, technological, and reliability indicators of Fregat sprinkling machines equipped with cleaning devices have rather high values, correspond to agrotechnical requirements, and exceed similar values inherent in the serial modifications of other sprinkling machines on average by 30-35 %.}, keywords = {Sprinkling Machine,Soil And Relief Conditions,Traction And Adhesion Properties,Cleaning Device}, url = {https://www.jmchemsci.com/article_135252.html}, eprint = {https://www.jmchemsci.com/article_135252_a20d11c95d906118a9ea6f062ab3887c.pdf} } @article { author = {Mansoorian, Seyed Mohammad Ali and Ebrahimimehr, Abbas Ali}, title = {Effective Methods and Techniques of Teaching English to Students of Medicine}, journal = {Journal of Medicinal and Chemical Sciences}, volume = {4}, number = {5}, pages = {484-491}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2651-4702}, eissn = {2651-4702}, doi = {10.26655/JMCHEMSCI.2021.5.9}, abstract = {The study followed two fundamental aims. The first aim of the study was to explore EFL teachers’ perceptions about effective teaching and learning and its second goal was to explore participants’ beliefs about the best methods and techniques of teaching. This is a survey that used a researcher-made questionnaire to garner data from the participants. It had two main dimensions, one focusing on the nature of children’s learning, and the other was focusing on methods and techniques of language teaching. The participants were EFL male and female teachers who were selected through a convenient sampling method from some language institutes in Shiraz. To analyze the data, the researcher made use of a one-sample t-test. The results showed that teachers’ awareness about language learning and teaching was higher than average. The mean scores of the participants in all the dimensions, including traditional concepts, constructivist concepts, and humanistic concepts, were higher than average. The results also depicted that teachers’ awareness about the methods and techniques of teaching was also higher than the average domain. The participants’ mean scores in all the dimensions of the grammar-translation method, communicative approach, and teaching practices were higher than average in the communicative approach.}, keywords = {Professional Development,professional teaching,teacher beliefs,teacher education,teacher perception}, url = {https://www.jmchemsci.com/article_135254.html}, eprint = {https://www.jmchemsci.com/article_135254_ebd458d5ada849e18a444c00f4e002c5.pdf} } @article { author = {Nesterov, V. G. and Dmitriev, V. N. and Igrunova, S. V. and Nesterova, E.V. and Kharchenko, U.A. and Anciferov, O.V.}, title = {Physiological Basis and Limitations of Diagnosis of Synchronous Registration of Surface Electrocardiogram of Patients with Cervical Cancer}, journal = {Journal of Medicinal and Chemical Sciences}, volume = {4}, number = {5}, pages = {492-496}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2651-4702}, eissn = {2651-4702}, doi = {10.26655/JMCHEMSCI.2021.5.10}, abstract = {This study highlights one of the areas of modern electrophysiology of the human heart in health and in case of cervical cancer - multichannel synchronous registration of an electrostatic field on the patient's body surface. The physiological basis of the research method, hardware, methods of data analysis and presentation of results are briefly discussed. It has been shown that the limitations of diagnosis of the proposed method of analysis and interpretation of the results of electrocardiographic study can be useful in the early diagnosis of comorbid pathology of patients with cervical cancer.}, keywords = {Physiological properties,synchronous registration,multichannel electrocardiogram,comorbid pathology,Cervical cancer}, url = {https://www.jmchemsci.com/article_135263.html}, eprint = {https://www.jmchemsci.com/article_135263_113c523244abf115be58c3d808042866.pdf} } @article { author = {Aldugiem, Murhaf and Abdelkader, Abeer and El-Soussi, Azza and Zeitoun, Tayseer and Abdelkader, Fadia Ahmed and Abdelrahem, Amal Sayed Ali and Abd-Elhamid, Masouda}, title = {Effect of Abdominal Massage on Gastrointestinal Outcomes of Critical Ill Patients with Enteral Feeding}, journal = {Journal of Medicinal and Chemical Sciences}, volume = {4}, number = {5}, pages = {497-507}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2651-4702}, eissn = {2651-4702}, doi = {10.26655/JMCHEMSCI.2021.5.11}, abstract = {Background: Life-threatening problems are risks for critically ill patients. Moreover, they need complex care with carful coordination. In addition, nutritional support considered as fundamental aspect of a standard care of critically ill patients. Objectives: We aimed at evaluating the abdominal massage effect on gastrointestinal outcomes of critical ill patients with enteral feeding.Methods: Quasi-experimental research design was used in this study. The Swedish massage technique for abdomen was carried out twice daily for five consecutive days by the trained researcher. A convenience sample of 60 critically adult males with enteral feeding participated voluntarily in the study.Results: The results of this study revealed that, gastric residual volume was low with the study group than the control group during intervention period after abdominal massage.  Also, a significant difference was noticed in last three days of the intervention between the study and control groups. Moreover, it was indicated that abdominal distension, vomiting, and constipation were low with the study group than the control group during the five consecutive days of intervention. Conclusion: This study provides promising evidence that massage of abdomen can be used with entirely fed critically ill patients to improve their gastrointestinal outcomes. This leads to a reduction in residual volume of gastric, distension of abdomen, constipation, and vomiting.}, keywords = {Abdominal Massage,enteral feeding,gastrointestinal outcome}, url = {https://www.jmchemsci.com/article_136101.html}, eprint = {https://www.jmchemsci.com/article_136101_924ca9651727932623f84132431bf5ba.pdf} } @article { author = {Valerievna Snarskaya, Ekaterina and Yurievna Shammazova, Ekaterina and Muzipovna Mukharyamova, Laysan and Rustemovich Zalyaev, Arthur}, title = {Covid-19 Vs Challenge to a New Health Care Reform}, journal = {Journal of Medicinal and Chemical Sciences}, volume = {4}, number = {5}, pages = {508-512}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2651-4702}, eissn = {2651-4702}, doi = {10.26655/JMCHEMSCI.2021.5.12}, abstract = {The absence of signs of legitimacy of power structures, and disagreement with the health policy lead to dissatisfaction, condemnation and protest moods among the population. This disagreement is manifested both at the level of consumers of services - ordinary citizens, and at the level of producers of services - the medical (professional) community. If until recently episodes with a low degree of public satisfaction with the quality of medical services were widely discussed in the media, recent years would have indicated protest moods in the professional group, portending the failure of health care reform. Today, one can hear the conventional wisdom everywhere that it is the medical community that must take full responsibility for solving the pandemic problem fully. However, the analysis of the transitional state of the modern public health system presented in the article, including in the context of the COVID-19 pandemic, shows the ability of this “state” to such challenges as political destabilization, public outcry, professional protests and much more. In fact, today we are witnessing a process of expanding the functions of the health care system from traditional, in particular, the provision of medical care to citizens, pharmaceutical activities, the development of state policy in the field of health care and social development, etc., to the area of non-specific and until recently marginal - we mean the ideological component, accumulating in wide layers of society, turns out to be capable of direct political action.}, keywords = {health policy,Transition,health system,Protest,Public Policy,Pandemic}, url = {https://www.jmchemsci.com/article_136130.html}, eprint = {https://www.jmchemsci.com/article_136130_c4610d68f0417de2608f1dddcf584f3c.pdf} } @article { author = {Permata Hardi, Hidayu and Zulfan Hendri, Ahmad and R. Brodjonegoro, Sakti}, title = {Increase of Neutrophil-Lymphocyte Ratio (NLR) during Urologic Laparoscopic Surgery with Intraoperative Complications in Dr. Sardjito Hospital}, journal = {Journal of Medicinal and Chemical Sciences}, volume = {4}, number = {5}, pages = {513-518}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2651-4702}, eissn = {2651-4702}, doi = {10.26655/JMCHEMSCI.2021.5.13}, abstract = {Laparoscopy is a minimally invasive surgery using advanced technology, so the resulting surgical wound is smaller than conventional surgery. Laparoscopy, especially in the field of urology, is known to cause complications in patients. Intraoperative complications will cause physiological stress that causes an inflammatory response in the body. Neutrophils are one of the most important cells in producing the inflammatory response in the acute phase. Meanwhile, lymphocytes are the main cellular components of the immune system that are mediated by T cells and humoral cells. This study was conducted retrospectively and reviewed the patient's medical record data from intraoperative to outpatient admission. The sample included 71 patients who underwent laparoscopic urology in 2017-2019. There was a difference in NLR values between pre surgery and post-surgery (p <0.05). It is known that the postoperative NLR value is higher than preoperative. In addition, it was known that there were differences in postoperative NLR values between patients who did not experience complications and those who had complications (p < 0.05). Where there is an increase in the postoperative NLR value in patients with complications, intraoperative complications lead to increased NLR. The greater the physiological stress experienced, the higher the NLR value. Increased NLR reflects poor output.}, keywords = {complication,Laparoscopy,NLR}, url = {https://www.jmchemsci.com/article_136136.html}, eprint = {https://www.jmchemsci.com/article_136136_50b690d7bcb1f4821a445c61f52f2b27.pdf} } @article { author = {Ivanova, Ekaterina Anatolevna and Gerasimova, Liudmila Ivanovna and Sharapova, Оlga Viktorovna and Bragina, Olga Nikolaevna and Bushueva, Elvira Valerianovna and Petrov, Andrey Georgievich and Mikhaylov, Mikhail Yurievich}, title = {Cardiac Conduction Disorders in Children with Community-Acquired Pneumonia}, journal = {Journal of Medicinal and Chemical Sciences}, volume = {4}, number = {5}, pages = {519-524}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2651-4702}, eissn = {2651-4702}, doi = {10.26655/JMCHEMSCI.2021.5.14}, abstract = {The purpose of this study was to evaluate the cardiac conduction in children with non-severe community-acquired pneumonia during inpatient treatment and period of convalescence by electrocardiographic examination. The study involved 166 children aged 1 to 17 years, patients with non-severe community-acquired pneumonia, undergoing inpatient treatment in Pediatric Hospital. On the second day of treatment, each child underwent a heart ECG. The control sample consisted of 271 healthy children. Then, after dispensary observation, children with abnormalities in cardiac conduction had another ECG. The study found that 76% of children with non-severe pneumonia had ECG changes. The majority of children had conduction disorders of different localization and degree. Intraventricular conduction disorder in pneumonia occurred in 38% of cases, 2.5 times more often than in the control sample. Considering pathology of heart excitability, 3.96% of children had signs of right atrium overload, and 2.85 % - of left ventricle. 70 % of children with conduction disorders still had these changes after the ECG study in dynamics. This study showed that children with pneumonia had significant changes in the electrophysiological activity of the heart, which may have persisted after the convalescence period. This group of patients requires special management tactics at the stage of therapy and rehabilitation.}, keywords = {children,community-acquired pneumonia,Electrocardiogram,teenagers}, url = {https://www.jmchemsci.com/article_136139.html}, eprint = {https://www.jmchemsci.com/article_136139_9ac0322a0020730c439cd35b2218f361.pdf} } @article { author = {Afrash, Mohammad Reza and Kazemi-Arpanahi, Hadi and Ranjbar, Parvaneh and Noupor, Raoof and Saki, Mojgan and Amraei, Morteza and Shanbehzadeh, Mostafa}, title = {Predictive Modeling of Hospital Length of Stay in COVID-19 Patients Using Machine Learning Algorithms}, journal = {Journal of Medicinal and Chemical Sciences}, volume = {4}, number = {5}, pages = {525-537}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2651-4702}, eissn = {2651-4702}, doi = {10.26655/JMCHEMSCI.2021.5.15}, abstract = {The rapid worldwide outbreak of COVID-19 has posed serious and unprecedented challenges to healthcare systems in predicting disease behavior, consequences and resource utilization. Therefore, predicting the Length of Stay (LOS) is necessary to ensure optimal allocate of scarce hospital resources. The purpose of this research was to construct a model for predicting COVID-19 patients' hospital LOS by multiple Machine Learning (ML) algorithms. Using a single-center registry, we studied the records of 1225 laboratory-confirmed COVID-19 hospitalized patients from February 9, 2020, to December 20, 2020. The most important clinical parameters in the COVID-19 LOS prediction were identified with a correlation coefficient at the P-value< 0.2. Then, the prediction models were developed based on seven ML techniques according to selected variables. Finally, to evaluate the performances of those models several standard quantitative measures includes accuracy, sensitivity, specificity and ROC curve were used to evaluate the proposed predictive models. After implementing feature selection, a total of 20 variables was identified as the most relevant predictors to build the prediction models. The results indicated that the best performance belonged to the Support Vector Machine (SVM) algorithm with the mean accuracy of 99.5%, mean specificity of 99.7%, mean sensitivity of 99.4%, and the standard deviation of 1.2. The SVM provided a reasonable level of accuracy and certainty in predicting the LOS in COVID-19 patients and potentially facilitates hospital bed management, turnover and optimized resource allocation. }, keywords = {COVID-19,Coronavirus,Machine Learning,Data mining,Length of stay}, url = {https://www.jmchemsci.com/article_136288.html}, eprint = {https://www.jmchemsci.com/article_136288_ded127813f780533ac83b009ac67bdba.pdf} }